Search Results - "Genome editing"

Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy by George D. Mcilroy, Sharon E. Mitchell, Weiping Han, Mirela Delibegović, Justin J. Rochford

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NCAPG Is a Promising Therapeutic Target Across Different Tumor Types by Cuicui Xiao, Jiao Gong, Yusheng Jie, Jing Cao, Zhongcheng Chen, Rong Li, Yutian Chong, Bo Hu, Qi Zhang

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Nanomaterials for mRNA‐based therapeutics: Challenges and opportunities by De‐feng Li, Qi‐song Liu, Mei‐feng Yang, Hao‐ming Xu, Min‐zheng Zhu, Yuan Zhang, Jing Xu, Cheng‐mei Tian, Jun Yao, Li‐sheng Wang, Yu‐jie Liang

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Regenerative Medicine, Disease Modelling, and Drug Discovery in Human Pluripotent Stem Cell-Derived Kidney Tissue by Navin Gupta, Koichiro Susa, Ryuji Morizane

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Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression by Hyunsuk Kim, Jinmo Sung, Ju Young Bae, Poongyeon Lee, Yun Kyu Oh, Hyunho Kim

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Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors by Hong Wang, Rui Guo, Zhonghua Du, Ling Bai, Lingyu Li, Jiuwei Cui, Wei Li, Andrew R. Hoffman, Ji-Fan Hu

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Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification by Sriram Vaidyanathan, Krist T. Azizian, A.K.M. Ashiqul Haque, Jordana M. Henderson, Ayal Hendel, Sabrina Shore, Justin S. Antony, Richard I. Hogrefe, Michael S.D. Kormann, Matthew H. Porteus, Anton P. McCaffrey

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Mutation Spectrum of Stickler Syndrome Type I and Genotype-phenotype Analysis in East Asian Population: a systematic review by Dan-Dan Wang, Feng-Juan Gao, Fang-Yuan Hu, Sheng-Hai Zhang, Ping Xu, Ji-Hong Wu

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TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs by Shingo Suzuki, R Geoffrey Sargent, Beate Illek, Horst Fischer, Alaleh Esmaeili-Shandiz, Michael J Yezzi, Albert Lee, Yanu Yang, Soya Kim, Peter Renz, Zhongxia Qi, Jingwei Yu, Marcus O Muench, Ashley I Beyer, Alessander O Guimarães, Lin Ye, Judy Chang, Eli J Fine, Thomas J Cradick, Gang Bao, Meghdad Rahdar, Matthew H Porteus, Tsuyoshi Shuto, Hirofumi Kai, Yuet W Kan, Dieter C Gruenert

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Ex Vivo COL7A1 Correction for Recessive Dystrophic Epidermolysis Bullosa Using CRISPR/Cas9 and Homology-Directed Repair by Araksya Izmiryan, Clarisse Ganier, Matteo Bovolenta, Alain Schmitt, Fulvio Mavilio, Alain Hovnanian

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Effective CRISPR/Cas9-based nucleotide editing in zebrafish to model human genetic cardiovascular disorders by Federico Tessadori, Helen I. Roessler, Sanne M. C. Savelberg, Sonja Chocron, Sarah M. Kamel, Karen J. Duran, Mieke M. van Haelst, Gijs van Haaften, Jeroen Bakkers

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Biallelic modification of IL2RG leads to severe combined immunodeficiency in pigs by Jung-Taek Kang, Bumrae Cho, Junghyun Ryu, Caitlin Ray, Eun-Jin Lee, Yun-Jin Yun, SunMi Ahn, JinSeok Lee, Dal-Young Ji, Nathaniel Jue, Sherrie Clark-Deener, Kiho Lee, Kwang-Wook Park

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A severe atherosclerosis mouse model on the resistant NOD background by Xugang Wang, Rong Huang, Lichen Zhang, Saichao Li, Jing Luo, Yanrong Gu, Zhijun Chen, Qianqian Zheng, Tianzhu Chao, Wenping Zheng, Xinhui Qi, Li Wang, Yinhang Wen, Yinming Liang, Liaoxun Lu

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Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse by Kevin J. Kauffman, Matthias A. Oberli, J. Robert Dorkin, Juan E. Hurtado, James C. Kaczmarek, Shivani Bhadani, Jeff Wyckoff, Robert Langer, Ana Jaklenec, Daniel G. Anderson

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Xenopus From Basic Biology to Disease Models in the Genomic Era

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Engineering the plant genome, transient gene silencing, meristematic gene expression and up regulation of flowering - The phase change in papaver bracteatum by Phani Raja Kumar Madam

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Cell Signaling in Model Plants

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Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect host. by Arunasalam Naguleswaran, Paula Fernandes, Shubha Bevkal, Ruth Rehmann, Pamela Nicholson, Isabel Roditi

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Light-activated green drugs: How we can use them in photodynamic therapy and mass-produce them with biotechnological tools by Emiliano Foresto, Pamela Gilardi, Luis Exequiel Ibarra, Ingrid Sol Cogno

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PCSK9 Antagonists: Clinical Efficacy and Main Trends in the Development of New Medicines by A. A. Nekipelova, R. N. Alyautdin

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