Search Results - "Genome editing"

Genetic Manipulation Strategies for β-Thalassemia: A Review by Nur Atikah Zakaria, Rosnah Bahar, Wan Zaidah Abdullah, Abdul Aziz Mohamed Yusoff, Shaharum Shamsuddin, Shaharum Shamsuddin, Shaharum Shamsuddin, Ridhwan Abdul Wahab, Muhammad Farid Johan

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A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020 by Mai H. Tran, Hajeung Park, Christopher L. Nobles, Pabalu Karunadharma, Li Pan, Guocai Zhong, Haimin Wang, Wenhui He, Tianling Ou, Gogce Crynen, Kelly Sheptack, Ian Stiskin, Huihui Mou, Michael Farzan

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CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments by Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul J. Coucke, Andy Willaert

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MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma by Chase K.A. Neumann, Daniel J. Silver, Varadharajan Venkateshwari, Renliang Zhang, C. Alicia Traughber, Christopher Przybycin, Defne Bayik, Jonathan D. Smith, Justin D. Lathia, Brian I. Rini, J. Mark Brown

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Deletion of PRAK Mitigates the Mitochondria Function and Suppresses Insulin Signaling in C2C12 Myoblasts Exposed to High Glucose by Ling Zhang, Jianguo Wang, Yu Tina Zhao, Patrycja Dubielecka, Gangjian Qin, Shougang Zhuang, Eugene Y Chin, Paul Y Liu, Ting C Zhao, Ting C Zhao

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Collagen COL22A1 maintains vascular stability and mutations in COL22A1 are potentially associated with intracranial aneurysms by Quynh V. Ton, Daniel Leino, Sarah A. Mowery, Nina O. Bredemeier, Pascal J. Lafontant, Allison Lubert, Suman Gurung, Janice L. Farlow, Tatiana M. Foroud, Joseph Broderick, Saulius Sumanas

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CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons by S. Schuster, E. Heuten, A. Velic, J. Admard, M. Synofzik, S. Ossowski, B. Macek, S. Hauser, L. Schöls

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Analysis of absolute amounts of two meiotic cohesin subunits, RAD21L and REC8, in mouse spermatocytes by Yuto TANIUCHI, Kazutaka HIRAIDE, Rilige SU, Kazune IJUIN, XingQiang WEI, Takuro HORII, Izuho HATADA, Jibak LEE

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The landscape of GWAS validation; systematic review identifying 309 validated non-coding variants across 130 human diseases by Ammar J. Alsheikh, Sabrina Wollenhaupt, Emily A. King, Jonas Reeb, Sujana Ghosh, Lindsay R. Stolzenburg, Saleh Tamim, Jozef Lazar, J. Wade Davis, Howard J. Jacob

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CRISPR/Cas9 RET Gene Knockout in Medullary Thyroid Carcinoma Cell-lines: Optimization and Validation by Marjan Zarif-Yeganeh, Dariush D Farhud, Azam Rahimpour, Sara Sheikholeslami, Setareh Shivaei, Mehdi Hedayati

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Identification and detection of a novel point mutation in the Chitin Synthase gene of Culex pipiens associated with diflubenzuron resistance. by Emmanouil A Fotakis, Valentina Mastrantonio, Linda Grigoraki, Daniele Porretta, Arianna Puggioli, Alexandra Chaskopoulou, Hugo Osório, Mylène Weill, Romeo Bellini, Sandra Urbanelli, John Vontas

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The Wheat Genome

Table of Contents: “…Introduction -- IWGSC RefSeq bread wheat reference genome sequence -- Wheat genomic resources and their role in wheat research -- Wheat genome structural and functional annotation -- The wheat transcriptome and discovery of functional gene networks -- Genome-wide resource development to accelerate gene discovery and functional analysis in wheat -- Genome-editing technology applications in wheat breeding -- Wheat genetic diversity explored through genomic approaches -- Dawn of the wheat pangenome: sequencing the genomes of 10+ elite lines -- Sequencing ancient wheat to illuminate the history of domestication -- Genome sequences from diploids and wild relatives of wheat for comparative genomics and alien Introgressions -- The impact of the durum wheat genome in identifying new germplasm for breeding -- Haplotype mapping in globally diverse germplasm for genomic-assisted wheat breeding -- Genome-informed discovery of genes and association with wheat traits -- Genomic insights on global journeys of adaptive wheat genes that brought us to modern wheat -- Genomic selection in wheat utilizing the reference sequence -- Rapid cloning of disease resistance genes in wheat. .…”
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Biotechnologies for Plant Mutation Breeding Protocols /

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Poultry: Breeding, Health, Nutrition, and Management

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Challenges in Treating Genodermatoses: New Therapies at the Horizon by Marie-Anne Morren, Eric Legius, Fabienne Giuliano, Smail Hadj-Rabia, Daniel Hohl, Christine Bodemer

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NRF2 Deficiency Attenuates Diabetic Kidney Disease in Db/Db Mice via Down-Regulation of Angiotensinogen, SGLT2, CD36, and FABP4 Expression and Lipid Accumulation in Renal Proximal... by Ke Su, Shui-Ling Zhao, Wen-Xia Yang, Chao-Sheng Lo, Isabelle Chenier, Min-Chun Liao, Yu-Chao Pang, Jun-Zheng Peng, Kana N. Miyata, Jean-Francois Cailhier, Jean Ethier, Jean-Baptiste Lattouf, Janos G. Filep, Julie R. Ingelfinger, Shao-Ling Zhang, John S. D. Chan

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Cell-targeted gene modification by delivery of CRISPR-Cas9 ribonucleoprotein complexes in pseudotyped lentivirus-derived nanoparticles by Ian Helstrup Nielsen, Anne Bruun Rovsing, Jacob Hørlück Janns, Emil Aagaard Thomsen, Albert Ruzo, Andreas Bøggild, Frederikke Nedergaard, Charlotte Thornild Møller, Thomas Boesen, Søren Egedal Degn, Jagesh V. Shah, Jacob Giehm Mikkelsen

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Sequential Accumulation of 'Driver' Pathway Mutations Induces the Upregulation of Hydrogen-Sulfide-Producing Enzymes in Human Colonic Epithelial Cell Organoids by Kelly Ascenção, Nahzli Dilek, Karim Zuhra, Katalin Módis, Toshiro Sato, Csaba Szabo

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Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo... by Fernanda Cristina Costa, Amanda Fortes Francisco, Shiromani Jayawardhana, Simone Guedes Calderano, Michael D Lewis, Francisco Olmo, Tom Beneke, Eva Gluenz, Jack Sunter, Samuel Dean, John Morrison Kelly, Martin Craig Taylor

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AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells by Chen X, Zhang X, Xu J, Zhao Y, Bao J, Zheng Z, Han J

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