Search Results - "Lipinski's rule of five"

Decrypting molecular mechanism insight of Phyllanthus emblica L. fruit in the treatment of type 2 diabetes mellitus by network pharmacology by Helal Uddin Chowdhury, Md. Adnan, Ki Kwang Oh, Dong Ha Cho

Connect to this object online.

Virtual screening-molecular docking-activity evaluation of Ailanthus altissima (Mill.) swingle bark in the treatment of ulcerative colitis by Shan-bo Ma, Lun Liu, Xiang Li, Yan-hua Xie, Xiao-peng Shi, Si-wang Wang

Connect to this object online.

Potential of fenugreek (Trigonella foenum-graecum L.) metabolites as dental residual ridge resorption inhibitors through estrogen receptor signaling: In silico study by Ester Handayani Lodra, Muhammad Chair Effendi, Nur Permatasari, Respati Suryanto Dradjat

Connect to this object online.

Antimicrobial analysis of honey against Staphylococcus aureus isolates from wound, ADMET properties of its bioactive compounds and in-silico evaluation against dihydropteroate synt... by Uwem Okon Edet, Elizabeth Nkagafel Mbim, Esu Ezeani, Okoroiwu Uchechi Henshaw, Oju R. Ibor, Ini Ubi Bassey, Edet Effiong Asanga, Ekpo Eyo Antai, Francisca O. Nwaokorie, Bassey Okon Edet, Glory P. Bebia, Curtis Tega, Clement I. Mboto, Ani Nkang, Ada Francesca Nneoyi-Egbe

Connect to this object online.

Quercetin and Kaempferol as Multi-Targeting Antidiabetic Agents against Mouse Model of Chemically Induced Type 2 Diabetes by Muhammad Ali, Mudassir Hassan, Siddique Akber Ansari, Hamad M. Alkahtani, Lamees S. Al-Rasheed, Shoeb Anwar Ansari

Connect to this object online.

Quinazolin-4-one derivatives lacking toxicity-producing attributes as glucokinase activators: design, synthesis, molecular docking, and in-silico ADMET prediction by Saurabh C. Khadse, Nikhil D. Amnerkar, Manasi U. Dave, Deepak K. Lokwani, Ravindra R. Patil, Vinod G. Ugale, Nitin B. Charbe, Vivekanand A. Chatpalliwar

Connect to this object online.

Homology modeling, molecular dynamics, and virtual screening of NorA efflux pump inhibitors of Staphylococcus aureus by Bhaskar BV, Babu TMC, Reddy NV, Rajendra W

Connect to this object online.

Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2 by Arun Bahadur Gurung, Mohammad Ajmal Ali, Joongku Lee, Mohammad Abul Farah, Khalid Mashay Al-Anazi

Connect to this object online.

Molecular simulation of compounds from n-hexane fraction of Sonchus arvensis L. leaves as SARS-CoV-2 antiviral through inhibitor activity targeting strategic viral protein by Dwi Kusuma Wahyuni, Sumrit Wacharasindhu, Wichanee Bankeeree, Hunsa Punnapayak, Hery Purnobasuki, Junairiah, Arif NM Ansori, Viol Dhea Kharisma, Arli Aditya Parikesit, Listyani Suhargo, Sehanat Prasongsuk

Connect to this object online.

Structure-based virtual screening and molecular dynamics of potential inhibitors targeting sodium-bile acid co-transporter of carcinogenic liver fluke Clonorchis sinensis. by Won Gi Yoo, Fuhong Dai, Jhang Ho Pak, Sung-Jong Hong, Jin-Ho Song

Connect to this object online.

Herbal combination from Moringa oleifera Lam. and Curcuma longa L. as SARS-CoV-2 antiviral via dual inhibitor pathway: A viroinformatics approach. by Viol Dhea Kharisma, Aggy Agatha, Arif Nur Muhammad Ansori, Muhammad Hermawan Widyananda, Wahyu Choirur Rizky, Tim Godefridus Antonius Ding, Marina Derkho, Irina Lykasova, Yulanda Antonius, Imam Rosadi, Rahadian Zainul

Connect to this object online.

Design, synthesis and screening of indole acetic acid-based tri-azo moieties as antioxidants, anti-microbial and cytotoxic agents by Maryam Javaid, Ihsan-Ul Haq, Humaira Nadeem, Humaira Fatima, Arif-Ullah Khan, Nadeem Irshad

Connect to this object online.

Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity by Ebru Koçak Aslan, Muhammed İhsan Han, Vagolu Siva Krishna, Rasoul Tamhaev, Cagatay Dengiz, Şengül Dilem Doğan, Christian Lherbet, Lionel Mourey, Tone Tønjum, Miyase Gözde Gündüz

Connect to this object online.

Identification of Novel Inhibitor of Enoyl-Acyl Carrier Protein Reductase (InhA) Enzyme in <i>Mycobacterium tuberculosis</i> from Plant-Derived Metabolites: An In Silico Study by Kratika Singh, Niharika Pandey, Firoz Ahmad, Tarun Kumar Upadhyay, Mohammad Hayatul Islam, Nawaf Alshammari, Mohd Saeed, Lamya Ahmed Al-Keridis, Rolee Sharma

Connect to this object online.

Computer-aided identification of Mycobacterium tuberculosis resuscitation-promoting factor B (RpfB) inhibitors from Gymnema sylvestre natural products by Mohibullah Shah, Fatiha Khan, Iqra Ahmad, Cun-Liang Deng, Asia Perveen, Anwar Iqbal, Umar Nishan, Aqal Zaman, Riaz Ullah, Essam A. Ali, Ke Chen

Connect to this object online.

Quercitrin neutralizes sPLA2IIa activity, reduces the inflammatory IL-6 level in PC3 cell lines, and exhibits anti-tumor activity in the EAC-bearing mice model by P. Sophiya, Deepadarshan Urs, Jafar K. Lone, A. S. Giresha, H. Krishna Ram, J. G. Manjunatha, Hamed A. El-Serehy, M. Narayanappa, J. Shankar, Ragini Bhardwaj, Sameer Ahmad Guru, K. K. Dharmappa

Connect to this object online.

In vivo and in silico evaluation of analgesic activity of Lippia alba by Md. Abdullah Aziz, Manna Mehedi, Mst. Irin Akter, Sadiur Rahman Sajon, Kishor Mazumder, Md. Sohel Rana

Connect to this object online.

MM/GB(PB)SA integrated with molecular docking and ADMET approach to inhibit the fat-mass-and-obesity-associated protein using bioactive compounds derived from food plants used in t... by Manisha Mandal, Shyamapada Mandal

Connect to this object online.

Unveiling novel inhibitors of dopamine transporter via in silico drug design, molecular docking, and bioavailability predictions as potential antischizophrenic agents by Sabitu Babatunde Olasupo, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba

Connect to this object online.

Natural Products as Inhibitors of COVID-19 Main Protease - A Virtual Screening by Molecular Docking by Marzieh Omrani, Mohammad Bayati, Parvaneh Mehrbod, Kamal Asmari Bardazard, Samad Nejad-Ebrahimi

Connect to this object online.