Search Results - "Medicinal Chemistry"

Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design by Lidia Ciccone, Nicoló Tonali, Susanna Nencetti, Elisabetta Orlandini

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Design and synthesis of novel pyrazolo[4,3-d]pyrimidines as potential therapeutic agents for acute lung injury by Bao Shi Wang, Xin Huang, Liu Zeng Chen, Ming Ming Liu, Jing Bo Shi

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Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides by Andrea Angeli, Marta Ferraroni, Alessandro Bonardi, Claudiu T. Supuran, Alessio Nocentini

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Pharmacological Potential of Lathyrane-Type Diterpenoids from Phytochemical Sources by Fátima Vela, Abdellah Ezzanad, Alan Christy Hunter, Antonio José Macías-Sánchez, Rosario Hernández-Galán

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Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping by Zhimin Zhang, Lili Gu, Beibei Wang, Wenhai Huang, Yanmin Zhang, Zhen Ma, Shenxin Zeng, Zhengrong Shen

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Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR using a statistical modelling approach by Katarzyna Jakimiuk, Suat Sari, Robert Milewski, Claudiu T. Supuran, Didem Şöhretoğlu, Michał Tomczyk

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Small molecule compounds with good anti-inflammatory activity reported in the literature from 01/2009 to 05/2021: a review by Ming Bian, Qian-qian Ma, Yun Wu, Huan-huan Du, Gong Guo-hua

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Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII by Sara Seršen, Katja Traven, Jakob Kljun, Iztok Turel, Claudiu T. Supuran

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N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors by Naresh Sunduru, Mona Svensson, Mariateresa Cipriano, Sania Marwaha, C. David Andersson, Richard Svensson, Christopher J. Fowler, Mikael Elofsson

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Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase by Rita Meleddu, Simona Distinto, Angela Corona, Enzo Tramontano, Giulia Bianco, Claudia Melis, Filippo Cottiglia, Elias Maccioni

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Phosphonate inhibitors of West Nile virus NS2B/NS3 protease by Marcin Skoreński, Aleksandra Milewska, Krzysztof Pyrć, Marcin Sieńczyk, Józef Oleksyszyn

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Antiglycoxidative properties of amantadine - a systematic review and comprehensive in vitro study by Miłosz Nesterowicz, Małgorzata Żendzian-Piotrowska, Jerzy Robert Ładny, Anna Zalewska, Mateusz Maciejczyk

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From Antarctica to cancer research: a novel human DNA topoisomerase 1B inhibitor from Antarctic sponge Dendrilla antarctica by Alessio Ottaviani, Joshua Welsch, Keli Agama, Yves Pommier, Alessandro Desideri, Bill J. Baker, Paola Fiorani

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Synthesis and bioevaluation of novel steroidal isatin conjugates derived from epiandrosterone/androsterone by Shaoyong Ke, Zhigang Zhang, Manli Liu, Wei Fang, Daye Huang, Zhongyi Wan, Ronghua Zhou, Kaimei Wang, Liqiao Shi

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Acipimox inhibits human carbonic anhydrases by Mattia Mori, Claudiu T. Supuran

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Inhibition of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with sulphonamides by Linda J. Urbański, Andrea Angeli, Vesa P. Hytönen, Anna Di Fiore, Giuseppina De Simone, Seppo Parkkila, Claudiu T. Supuran

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Inhibition of the α-carbonic anhydrase from Vibrio cholerae with amides and sulfonamides incorporating imidazole moieties by Daniela De Vita, Andrea Angeli, Fabiana Pandolfi, Martina Bortolami, Roberta Costi, Roberto Di Santo, Elisabetta Suffredini, Mariangela Ceruso, Sonia Del Prete, Clemente Capasso, Luigi Scipione, Claudiu T. Supuran

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Synthesis of chiral pyrazolo[4,3-e][1,2,4]triazine sulfonamides with tyrosinase and urease inhibitory activity by Mariusz Mojzych, Paweł Tarasiuk, Katarzyna Kotwica-Mojzych, Muhammad Rafiq, Sung-Yum Seo, Michał Nicewicz, Emilia Fornal

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Subnanomolar indazole-5-carboxamide inhibitors of monoamine oxidase B (MAO-B) continued: indications of iron binding, experimental evidence for optimised solubility and brain penet... by Nikolay T. Tzvetkov, Liudmil Antonov

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Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson's disease by Zhongcheng Cao, Xingyue Wang, Tianlong Zhang, Xianwu Fu, Fan Zhang, Jiang Zhu

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