Search Results - "Medicinal Chemistry"

Newer human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents by Chetan P. Shah, Prashant S. Kharkar

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Carbonic anhydrase IX as a novel candidate in liquid biopsy by Ozen Ozensoy Guler, Claudiu. T. Supuran, Clemente Capasso

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Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties by Andrea Angeli, Mariana Pinteala, Stelian S. Maier, Sonia Del Prete, Clemente Capasso, Bogdan C. Simionescu, Claudiu T. Supuran

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3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors by Aleksandrs Pustenko, Dmitrijs Stepanovs, Raivis Žalubovskis, Daniela Vullo, Andris Kazaks, Janis Leitans, Kaspars Tars, Claudiu T. Supuran

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4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-Toxoplasma gondii agents by Adrian Bekier, Lidia Węglińska, Agata Paneth, Piotr Paneth, Katarzyna Dzitko

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Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms by Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Bruno Cerra, Antimo Gioiello, Claudiu T. Supuran

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Purification and characterisation of glutathione reductase from scorpionfish (scorpaena porcus) and investigation of heavy metal ions inhibition by Kübra Işık, Ercan Soydan

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Sulphonamide inhibition studies of the β-carbonic anhydrase from the bacterial pathogen Clostridium perfringens by Daniela Vullo, R. Siva Sai Kumar, Andrea Scozzafava, James G. Ferry, Claudiu T. Supuran

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Design, synthesis and evaluation of 2-aryl benzoxazoles as promising hit for the A2A receptor by Romain Duroux, Nicolas Renault, Joana Esteves Cuelho, Laurence Agouridas, David Blum, Luisa V. Lopes, Patricia Melnyk, Saïd Yous

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Nanoemulsions of sulfonamide carbonic anhydrase inhibitors strongly inhibit the growth of Trypanosoma cruzi by Alane Beatriz Vermelho, Verônica da Silva Cardoso, Eduardo Ricci Junior, Elisabete Pereira dos Santos, Claudiu T. Supuran

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A new era for the design of TRPV1 antagonists and agonists with the use of structural information and molecular docking of capsaicin-like compounds by Julio Caballero

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Identification of phenazine analogue as a novel scaffold for thioredoxin reductase I inhibitors against Hep G2 cancer cell lines by Jianming Liao, Linlin Wang, Zhongxi Wu, Zhixiang Wang, Jun Chen, Yucheng Zhong, Feng Jiang, Yuanyuan Lu

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A comprehensive review of cycloastragenol: Biological activity, mechanism of action and structural modifications by Mengting He, Ke Wang, Haojie Che, Huifang Wang, Kan Yang, Guiming Zhang, Jingchun Yao, Jinxin Wang

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Discovery and Optimization of Selective Inhibitors of Meprin α (Part II) by Chao Wang, Juan Diez, Hajeung Park, Christoph Becker-Pauly, Gregg B. Fields, Timothy P. Spicer, Louis D. Scampavia, Dmitriy Minond, Thomas D. Bannister

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Water permeability is a measure of severity in acute appendicitis by Nicola Pini, Viktoria A. Pfeifle, Urs Kym, Simone Keck, Virginie Galati, Stefan Holland-Cunz, Stephanie J. Gros

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Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor by Rosa Maria Vitale, Lina Antenucci, Margherita Gavagnin, Gennaro Raimo, Pietro Amodeo

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Relevance of Fluorinated Ligands to the Design of Metallodrugs for Their Potential Use in Cancer Treatment by José C. Páez-Franco, Miriam R. Zermeño-Ortega, Carmen Myriam de la O-Contreras, Daniel Canseco-González, Jesus R. Parra-Unda, Alcives Avila-Sorrosa, Raúl G. Enríquez, Juan M. Germán-Acacio, David Morales-Morales

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A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors by Manuel A. Llanos, María L. Sbaraglini, María L. Villalba, María D. Ruiz, Carolina Carrillo, Catalina Alba Soto, Alan Talevi, Andrea Angeli, Seppo Parkkila, Claudiu T. Supuran, Luciana Gavernet

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Lipoxygenase inhibition and molecular docking studies of secondary metabolites from the leaves of Alstonia scholaris by Salome Y. Ghansenyuy, Kenneth O. Eyong, Pierre Yemback, Lateef Mehreen, Vincent de Paul N. Nziko, Muhammad S. Ali, Gabriel N. Folefoc

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Synthesis and in vivo anti-ulcer evaluation of some novel piperidine linked dihydropyrimidinone derivatives by Mashooq Ahmad Bhat, Mohamed A. Al-Omar, Ahmed M. Naglah

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