Search Results - "Medicinal Chemistry"

Glucokinase as an emerging anti-diabetes target and recent progress in the development of its agonists by Yixin Ren, Li Li, Li Wan, Yan Huang, Shuang Cao

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The multifaceted nature of plant acid phosphatases: purification, biochemical features, and applications by Lokesh Sharma, Amol Kahandal, Anant Kanagare, Atul Kulkarni, Chandrakant K. Tagad

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New Series of VEGFR-2 Inhibitors and Apoptosis Enhancers: Design, Synthesis and Biological Evaluation by Abdallah AE, Mabrouk RR, Elnagar MR, Farrag AM, Kalaba MH, Sharaf MH, El-Fakharany EM, Bakhotmah DA, Elkaeed EB, Al Ward MMS

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Enzyme Inhibitors and Activators

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Synthesis and carbonic anhydrase I, II, VII, and IX inhibition studies with a series of benzo[d]thiazole-5- and 6-sulfonamides by Morteza Abdoli, Andrea Angeli, Murat Bozdag, Fabrizio Carta, Ali Kakanejadifard, Hamid Saeidian, Claudiu T. Supuran

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Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties by Sinan Bilginer, Baris Gonder, Halise Inci Gul, Ruya Kaya, Ilhami Gulcin, Baris Anil, Claudiu T. Supuran

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Chemically stable inhibitors of 14-3-3 protein-protein interactions derived from BV02 by Leire Iralde-Lorente, Ylenia Cau, Letizia Clementi, Lorenzo Franci, Giusy Tassone, Daniela Valensin, Mattia Mori, Adriano Angelucci, Mario Chiariello, Maurizio Botta

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Screening the dermatological potential of Plectranthus species components: antioxidant and inhibitory capacities over elastase, collagenase and tyrosinase by Joana M. Andrade, Eva María Domínguez-Martín, Marisa Nicolai, Célia Faustino, Luís Monteiro Rodrigues, Patrícia Rijo

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Development and clinical advancement of small molecules for ex vivo expansion of hematopoietic stem cell by Jiaxing Li, Xiao Wang, Jiayu Ding, Yasheng Zhu, Wenjian Min, Wenbing Kuang, Kai Yuan, Chengliang Sun, Peng Yang

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Carbonic anhydrase modulation of emotional memory. Implications for the treatment of cognitive disorders by Patrizio Blandina, Gustavo Provensi, Maria Beatrice Passani, Clemente Capasso, Claudiu T. Supuran

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Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli by Liang Peng, Liting Zeng, Hongwei Jin, Lixin Yang, Yi Xiao, Ziquan Lan, Zhanpeng Yu, Shi Ouyang, Liangren Zhang, Ning Sun

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Anti-obesity carbonic anhydrase inhibitors: challenges and opportunities by Claudiu T. Supuran

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Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure-activity relationship by Carina Proença, Marisa Freitas, Daniela Ribeiro, Sara M. Tomé, Eduardo F. T. Oliveira, Matilde F. Viegas, Alberto N. Araújo, Maria J. Ramos, Artur M. S. Silva, Pedro A. Fernandes, Eduarda Fernandes

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Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity by Dong-Jun Fu, Ting Wang

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Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5 by Soyoung Hwang, Jung Yun Kang, Min Jae Kim, Dong Min Shin, Jeong Hee Hong

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Psychoactive substances belonging to the amphetamine class potently activate brain carbonic anhydrase isoforms VA, VB, VII, and XII by Andrea Angeli, Fabio Vaiano, Francesco Mari, Elisabetta Bertol, Claudiu T. Supuran

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Design, synthesis and antitumor activity of 3,4,5-Trisubstituted Isoxazoles by Kanghui Duan, Fuxing Tan, Hongming Xie, Haiwang Liu, Yingjun Zhang, Huanfeng Jiang, Wanqing Wu

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Fragment-based design, synthesis and biological evaluation of theophylline derivatives as ATAD2 inhibitors in BT-549 cells by Dahong Yao, Jieshu You, Xuetao Yang, Jin Zhang, Xiaojun Yao

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Different chemical proteomic approaches to identify the targets of lapatinib by Tatjana Kovačević, Krunoslav Nujić, Mario Cindrić, Snježana Dragojević, Adrijana Vinter, Amela Hozić, Milan Mesić

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Biological Activities of Ruthenium NHC Complexes: An Update by Alessia Catalano, Annaluisa Mariconda, Maria Stefania Sinicropi, Jessica Ceramella, Domenico Iacopetta, Carmela Saturnino, Pasquale Longo

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