Search Results - "Medicinal Chemistry"

Unraveling the Neuroprotective Effect of Natural Bioactive Compounds Involved in the Modulation of Ischemic Stroke by Network Pharmacology by Juan Carlos Gomez-Verjan, Emmanuel Alejandro Zepeda-Arzate, José Alberto Santiago-, Edgar Antonio Estrella-Parra, Nadia Alejandra Rivero-Segura

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Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors by Suresh Velnati, Alberto Massarotti, Annamaria Antona, Maria Talmon, Luigia Grazia Fresu, Alessandra Silvia Galetto, Daniela Capello, Alessandra Bertoni, Valentina Mercalli, Andrea Graziani, Gian Cesare Tron, Gianluca Baldanzi

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Hydroxyapatite-polymer nanocomposites for drug delivery applications: A mini review by Farnaz Behmagham, Shahad Mohammed Dhiaa, Abbas Hameed Abdul Hussein, Usama Kadem Radi, Hiba Mushtaq, Ameer Hassan Idan, Esmail Vessally

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Dietary inclusion of royal jelly modulates gene expression and activity of oxidative stress enzymes in zebrafish by Ercüment Aksakal, Deniz Ekinci, Claudiu T. Supuran

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Synthesis and structure-activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis by Ildikó Bacsa, Bianka Edina Herman, Rebeka Jójárt, Kevin Stefán Herman, János Wölfling, Gyula Schneider, Mónika Varga, Csaba Tömböly, Tea Lanišnik Rižner, Mihály Szécsi, Erzsébet Mernyák

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Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke, Schistosoma mansoni by Susanna Haapanen, Andrea Angeli, Martti Tolvanen, Reza Zolfaghari Emameh, Claudiu T. Supuran, Seppo Parkkila

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Watermelon: setup and validation of an in silico fragment-based approach by Miriana Di Stefano, Salvatore Galati, Lisa Piazza, Francesca Gado, Carlotta Granchi, Marco Macchia, Antonio Giordano, Tiziano Tuccinardi, Giulio Poli

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Design, synthesis and evaluation of OA-tacrine hybrids as cholinesterase inhibitors with low neurotoxicity and hepatotoxicity against Alzheimer's disease by Huali Yang, Hongwei Jia, Minghui Deng, Kaicheng Zhang, Yaoyang Liu, Yang Liu, Maosheng Cheng, Wei Xiao

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Towards discovery of new leishmanicidal scaffolds able to inhibit Leishmania GSK-3 by Paula Martínez de Iturrate, Victor Sebastián-Pérez, Montserrat Nácher-Vázquez, Catherine S. Tremper, Despina Smirlis, Julio Martín, Ana Martínez, Nuria E. Campillo, Luis Rivas, Carmen Gil

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Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity by Laureano L. Sabatier, Pablo H. Palestro, Andrea V. Enrique, Valentina Pastore, María L. Sbaraglini, Pedro Martín, Luciana Gavernet

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Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors by Xiaorui Han, Pingping Lan, Qianfeng Chen, Hua Liu, Zhongwen Chen, Tiantian Wang, Zengtao Wang

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Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines by Halise Inci Gul, Ebru Mete, Parham Taslimi, Ilhami Gulcin, Claudiu T. Supuran

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Benzofuran-appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies by Malose J. Mphahlele, Marole M. Maluleka, Abimbola Aro, Lyndy J. McGaw, Yee Siew Choong

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Design, synthesis and structure-activity studies of amino acids conjugated quinazolinone-Schiff's bases as potential antioxidant and anti-inflammatory agents by Santosh Kumar Verma, Rameshwari Verma, K.P. Rakesh, D. Channe Gowda

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The NMR studies of CMP inhibition of polysialylation by Bo Lu, Si-Ming Liao, Xue-Hui Liu, Shi-Jie Liang, Jun Huang, Mei Lin, Li Meng, Qing-Yan Wang, Ri-Bo Huang, Guo-Ping Zhou

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Discovery of potent histone deacetylase inhibitors with modified phenanthridine caps by Wenli Fan, Lin Zhang, Xuejiang Wang, Haiyong Jia, Lei Zhang

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Synthesis of 2,7-diarylpyrazolo [1,5-a] pyrimidine derivatives with antitumor activity. Theoretical identification of targets by Andrés Ballesteros-Casallas, Margot Paulino, Pietro Vidossich, Carol Melo, Elizabeth Jiménez, Juan-Carlos Castillo, Jaime Portilla, Gian Pietro Miscione

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New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling by Alba Vicente-Blázquez, Myriam González, Manuel Medarde, Faustino Mollinedo, Rafael Peláez

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Synthesis of new Schiff bases bearing 1,2,4-triazole, thiazolidine and chloroazetidine moieties and their pharmacological evaluation by Nadia G. Kandile, Mansoura I. Mohamed, Hind M. Ismaeel

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Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate by Matthew K. Craft, Grover L. Waldrop

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