Search Results - "Medicinal Chemistry"

Unveiling the interaction profile of rosmarinic acid and its bioactive substructures with serum albumin by Christina Papaemmanouil, Maria V. Chatziathanasiadou, Christos Chatzigiannis, Eleni Chontzopoulou, Thomas Mavromoustakos, Simona Golic Grdadolnik, Andreas G. Tzakos

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Design, synthesis and biological evaluation of novel tetrahydrothieno [2,3-c]pyridine substitued benzoyl thiourea derivatives as PAK1 inhibitors in triple negative breast cancer by Dahong Yao, Jian Huang, Jinhui Wang, Zhendan He, Jin Zhang

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Rational design, optimization, and biological evaluation of novel α-Phosphonopropionic acids as covalent inhibitors of Rab geranylgeranyl transferase by Joanna Małolepsza, Aleksandra Marchwicka, Remigiusz A. Serwa, Sanna P. Niinivehmas, Olli T. Pentikäinen, Edyta Gendaszewska-Darmach, Katarzyna M. Błażewska

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Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis by Junmin Zhang, Zai-Qin Zheng, Qianhe Xu, Ya Li, Kun Gao, Jianguo Fang

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Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents by Juliusz Maksymilian Walczak, Dorota Iwaszkiewicz-Grześ, Michalina Ziomkowska, Magdalena Śliwka-Kaszyńska, Mateusz Daśko, Piotr Trzonkowski, Grzegorz Cholewiński

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Stereospecific antiseizure activity in mouse and rat epilepsy models by a pyridinium inhibitor of TNFα/NFκB signaling by Bette S. Pollard, Zhiwei Wen, Kenneth A. Jacobson, John R. Pollard

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Osteopontin - a biomarker of disease, but also of stage stratification of the functional myocardial contractile deficit by chronic ischaemic heart disease by Bogdan-Ioan Coculescu, Gheorghe Manole, Gabi Valeriu Dincă, Elena Claudia Coculescu, Cristina Berteanu, Cristina Mariana Stocheci

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Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1 by Bianka Edina Herman, Anita Kiss, János Wölfling, Erzsébet Mernyák, Mihály Szécsi, Gyula Schneider

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Design, synthesis, and biological evaluation of thiazole/thiadiazole carboxamide scaffold-based derivatives as potential c-Met kinase inhibitors for cancer treatment by Xiang Nan, Qiu-Xu Wang, Shao-Jun Xing, Zhi-Gang Liang

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Synthesis and molecular docking studies of some 4-phthalimidobenzenesulfonamide derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors by Zeynep Soyer, Sirin Uysal, Sulunay Parlar, Ayse Hande Tarikogullari Dogan, Vildan Alptuzun

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Suppression of lipopolysaccharide-induced COX-2 expression via p38MAPK, JNK, and C/EBPβ phosphorylation inhibition by furomagydarin A, a benzofuran glycoside from Magydaris pastina... by Shiu-Wen Huang, Ming Jen Hsu, Hsiu-Chen Chen, Rita Meleddu, Simona Distinto, Elias Maccioni, Filippo Cottiglia

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Liposomic nano particles in the treatment of colorectal and ovarian cancer by Sheikh Rezzak Ali, Chinmoyee Deori, Gaurab Kr Gogoi, Naba Jyoti Borah, Prajnyan Prasad Kalita, Rubina Chowdhury, Simran Kaur, Bibhuti Bhusan Kakoti

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Design, synthesis and biological evaluation of novel diarylpyridine derivatives as tubulin polymerisation inhibitors by Shanbo Yang, Chao Wang, Lingyu Shi, Jing Chang, Yujing Zhang, Jingsen Meng, Wenjing Liu, Jun Zeng, Renshuai Zhang, Yingchun Shao, Dongming Xing

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Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases by Ashley A. Burke, Elizabeth S. Severson, Shreya Mool, Maria J. Solares Bucaro, Frederick T. Greenaway, Charles E. Jakobsche

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Reliable chromatographic assay for measuring of indoleamine 2,3-dioxygenase 1 (IDO1) activity in human cancer cells by Ilona Sadok, Kamila Rachwał, Ilona Jonik, Magdalena Staniszewska

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A highly potent and selective inhibitor Roxyl-WL targeting IDO1 promotes immune response against melanoma by Guangwei Xu, Tianqi Wang, Yongtao Li, Zhi Huang, Xin Wang, Jianyu Zheng, Shengyong Yang, Yan Fan, Rong Xiang

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Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibit... by Daseul Im, Hyungwoo Moon, Jingwoong Kim, Youri Oh, Miyoung Jang, Jung-Mi Hah

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Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB by Yaoyao Yan, Qi Lv, Feilong Zhou, Yujie Jian, Liu Xinhua, Xing Chen, Yong Hu

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Inhibition of African swine fever virus protease by myricetin and myricitrin by Seri Jo, Suwon Kim, Dong Hae Shin, Mi-Sun Kim

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Flavonoids as inhibitors of human neutrophil elastase by Katarzyna Jakimiuk, Jakub Gesek, Atanas G. Atanasov, Michał Tomczyk

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