Search Results - "Medicinal Chemistry"

The protective role of jervine against radiation-induced gastrointestinal toxicity by Selvinaz Yakan, Tuba Aydin, Canan Gulmez, Ozkan Ozden, Kivilcim Eren Erdogan, Yusuf Kenan Daglioglu, Fundagul Andic, Onur Atakisi, Ahmet Cakir

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Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach by Raja Solomon Viswas, Sheetal Pundir, Hoyun Lee

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Polymeric microspheres redefining the landscape of colon-targeted delivery: A contemporary update by Raosaheb S. Shendge, Tejas S. Zalte, Shubhangi B. Khade

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Diaryl azo derivatives as anti-diabetic and antimicrobial agents: synthesis, in vitro, kinetic and docking studies by Tehreem Tahir, Mirza Imran Shahzad, Rukhsana Tabassum, Muhammad Rafiq, Muhammad Ashfaq, Mubashir Hassan, Katarzyna Kotwica-Mojzych, Mariusz Mojzych

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Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae by Alessio Nocentini, Chad S. Hewitt, Margaret D. Mastrolorenzo, Daniel P. Flaherty, Claudiu T. Supuran

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Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells by Hyeong jae Kim, Jeong Hee Hong

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Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety by Xianqing Deng, Mingxia Song

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Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group by Pasquale Linciano, Luca Pinzi, Silvia Belluti, Ugo Chianese, Rosaria Benedetti, Davide Moi, Lucia Altucci, Silvia Franchini, Carol Imbriano, Claudia Sorbi, Giulio Rastelli

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Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors by Loghman Firoozpour, Lixin Gao, Setareh Moghimi, Parvin Pasalar, Jamshid Davoodi, Ming-Wei Wang, Zahra Rezaei, Armin Dadgar, Hoda Yahyavi, Massoud Amanlou, Alireza Foroumadi

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Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers by Chao Wang, Yuelin Li, Zi Liu, Zeyu Wang, Zihan Liu, Shuai Man, Yujing Zhang, Kai Bao, Yingliang Wu, Qi Guan, Daiying Zuo, Weige Zhang

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Upregulation of p53 through induction of MDM2 degradation: improved potency through the introduction of an alkylketone sidechain on the anthraquinone core by Ravi Tripathi, Abiodun Anifowose, Wen Lu, Xiaoxiao Yang, Binghe Wang

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Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors by Ibrahim M. Salem, Samia M. Mostafa, Ismail Salama, Osama I. El-Sabbagh, Wael A. H. Hegazy, Tarek S. Ibrahim

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Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFRWT and EGFRT790M by Moustafa O. Aboelez, Amany Belal, Guangya Xiang, Xiang Ma

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Microwave-assisted organic synthesis of pyrroles (Review) by Emilio Mateev, Ali Irfan, Alexandrina Mateeva, Maya Georgieva, Alexander Zlatkov

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Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase by Maria Luisa Di Paolo, Manuela Cervelli, Paolo Mariottini, Alessia Leonetti, Fabio Polticelli, Michela Rosini, Andrea Milelli, Filippo Basagni, Rina Venerando, Enzo Agostinelli, Anna Minarini

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Inhibition of the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa with monothiocarbamates by Alessio Nocentini, Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A.S. Alasmary, Zeid AlOthman, Clemente Capasso, Fabrizio Carta, Paola Gratteri, Claudiu T. Supuran

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Structure-activity relationship investigation of benzamide and picolinamide derivatives containing dimethylamine side chain as acetylcholinesterase inhibitors by Xiao-hui Gao, Lin-bo Liu, Hao-ran Liu, Jing-jing Tang, Lu Kang, Hongnian Wu, Peiwu Cui, Jianye Yan

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Functionality study of chalcone-hydroxypyridinone hybrids as tyrosinase inhibitors and influence on anti-tyrosinase activity by L. Ravithej Singh, Yu-Lin Chen, Yuan-Yuan Xie, Wei Xia, Xing-Wen Gong, Robert C. Hider, Tao Zhou

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Bioorganometallic Compounds as Novel Drug Targets against Schistosomiasis in Sub-Saharan Africa: An alternative to Praziquantel? by Cuma Cumisa Ndamse, Priscilla Masamba, Abidemi Paul Kappo

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Novel synthesized seleno-glycoconjugates as cosmeceutical ingredients: Antioxidant activity and in vitro skin permeation by Giovanna Cimmino, Mauro De Nisco, Cristina Alonso, Claudia Gravina, Vincenzo Piscopo, Reinier Lemos, Luisa Coderch, Simona Piccolella, Severina Pacifico, Silvana Pedatella

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