Search Results - "Medicinal Chemistry"

Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors by Suleyman Akocak, Nabih Lolak, Silvia Bua, Claudiu T. Supuran

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Design, synthesis, and evaluation of novel stilbene derivatives that degrade acidic nucleoplasmic DNA-binding protein 1 (And1) and synergize with PARP1 inhibitor in NSCLC cells by Leyuan Chen, Zhonghao Ren, Yunze Zhang, Wenbin Hou, Yiliang Li

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Chemical composition and enzyme inhibition of Phytolacca dioica L. seeds extracts by Amalia Di Petrillo, Ana María González-Paramás, Antonella Rosa, Valeria Ruggiero, Fabio Boylan, Amit Kumar, Francesca Pintus, Celestino Santos-Buelga, Antonella Fais, Benedetta Era

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In vitro α-glucosidase inhibition by Brazilian medicinal plant extracts characterised by ultra-high performance liquid chromatography coupled to mass spectrometry by Mariacaterina Lianza, Ferruccio Poli, Alan Menezes do Nascimento, Aline Soares da Silva, Thamirys Silva da Fonseca, Marcos Vinicius Toledo, Rosineide Costa Simas, Andréa Rodrigues Chaves, Gilda Guimarães Leitão, Suzana Guimarães Leitão

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Imidazopyridine-fused [1,3]diazepinones: modulations of positions 2 to 4 and their impacts on the anti-melanoma activity by Paul Le Baccon-Sollier, Yohan Malki, Morgane Maye, Lamiaa M. A. Ali, Laure Lichon, Pierre Cuq, Laure-Anaïs Vincent, Nicolas Masurier

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Evaluation of sulphonamide derivatives acting as inhibitors of human carbonic anhydrase isoforms I, II and Mycobacterium tuberculosis β-class enzyme Rv3273 by Tanvi V. Wani, Silvia Bua, Pravin S. Khude, Abdul H. Chowdhary, Claudiu T. Supuran, Mrunmayee P. Toraskar

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Experimental and computational models to understand protein-ligand, metal-ligand and metal-DNA interactions pertinent to targeted cancer and other therapies by Vaishali M. Patil, Satya P. Gupta, Neeraj Masand, Krishnan Balasubramanian

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Tripeptides conjugated with thiosemicarbazones: new inhibitors of tyrosinase for cosmeceutical use by Patrycja Ledwoń, Waldemar Goldeman, Katarzyna Hałdys, Michał Jewgiński, Greta Calamai, Joanna Rossowska, Anna Maria Papini, Paolo Rovero, Rafał Latajka

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Effect of cinnamamides on atopic dermatitis through regulation of IL-4 in CD4+ cells by Eun-Ju Choi, Young Bae Ryu, Yujiao Tang, Bo Ram Kim, Woo Song Lee, Trishna Debnath, Meiqi Fan, Hyun-Su Lee, Eun-Kyung Kim

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Design, synthesis, and biological evaluation of multiple targeting antimalarials by Yiqing Yang, Tongke Tang, Xiaolu Li, Thomas Michel, Liqin Ling, Zhenghui Huang, Maruthi Mulaka, Yue Wu, Hongying Gao, Liguo Wang, Jing Zhou, Brigitte Meunier, Hangjun Ke, Lubin Jiang, Yu Rao

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Design of potent fluoro-substituted chalcones as antimicrobial agents by Serdar Burmaoglu, Oztekin Algul, Arzu Gobek, Derya Aktas Anil, Mahmut Ulger, Busra Gul Erturk, Engin Kaplan, Aylin Dogen, Gönül Aslan

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Synthesis and antimicrobial activity of aminoalkyl resveratrol derivatives inspired by cationic peptides by Rubén Cebrián, Ricardo Lucas, María Victoria Fernández-Cantos, Koen Slot, Pablo Peñalver, Marta Martínez-García, Antonio Párraga-Leo, María Violante de Paz, Federico García, Oscar P. Kuipers, Juan Carlos Morales

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Preparation, carbonic anhydrase enzyme inhibition and antioxidant activity of novel 7-amino-3,4-dihydroquinolin-2(1H)-one derivatives incorporating mono or dipeptide moiety by Hasan Küçükbay, Zeynep Gönül, F. Zehra Küçükbay, Andrea Angeli, Gianluca Bartolucci, Claudiu T. Supuran

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Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation by Paolo Guglielmi, Giulia Rotondi, Daniela Secci, Andrea Angeli, Paola Chimenti, Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Simone Carradori, Claudiu T. Supuran

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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs by Raed Shalaby, Jacobus P. Petzer, Anél Petzer, Usman M. Ashraf, Ealla Atari, Fawaz Alasmari, Sivarajan Kumarasamy, Youssef Sari, Ashraf Khalil

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Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1) by Zhimin Zhang, Xinyue Chang, Chixiao Zhang, Shenxin Zeng, Meihao Liang, Zhen Ma, Zunyuan Wang, Wenhai Huang, Zhengrong Shen

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Purification and biochemical characterization of a novel thermostable serine alkaline protease from Aeribacillus pallidus C10: a potential additive for detergents by Vildan Yildirim, Mustafa Ozkan Baltaci, Ilknur Ozgencli, Melda Sisecioglu, Ahmet Adiguzel, Gulsah Adiguzel

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Synthesis and discovery of the first potent proteolysis targeting chimaera (PROTAC) degrader of AIMP2-DX2 as a lung cancer drug by BoRa Lee, Dae Gyu Kim, Aram Lee, Young Mi Kim, Lianji Cui, Sunghoon Kim, Inhee Choi

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Synthesis, telomerase inhibitory and anticancer activity of new 2-phenyl-4H-chromone derivatives containing 1,3,4-oxadiazole moiety by Xu Han, Yun Long Yu, Duo Ma, Zhao Yan Zhang, Xin Hua Liu

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An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65 by Giulio Poli, Gian Carlo Demontis, Andrea Sodi, Alessandro Saba, Stanislao Rizzo, Marco Macchia, Tiziano Tuccinardi

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