Search Results - "Medicinal Chemistry"

Hybrid inhibitors of DNA and HDACs remarkably enhance cytotoxicity in leukaemia cells by Yoojin Song, Sun You Park, Zhexue Wu, Kwang-Hyeon Liu, Young Ho Seo

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Discovery of coumaric acid derivatives hinted by coastal marine source to seek for uric acid lowering agents by Yu-Shun Yang, Bin Wang, Junzhong Liu, Qin Li, Qin-Cai Jiao, Pei Qin

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Novel piperazine-chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation by Marwa F. Ahmed, Eman Y. Santali, Radwan El-Haggar

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Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer's disease agents by Yinling Yun, Yuhang Miao, Xiaoya Sun, Jie Sun, Xiaojing Wang

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Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents by Rania Helmy Abd El-Hameed, Amira Ibrahim Sayed, Shima Mahmoud Ali, Mohamed A. Mosa, Zainab M. Khoder, Samar Said Fatahala

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Inhibition behaviours of some phenolic acids on rat kidney aldose reductase enzyme: an in vitro study by Zuhal Alim, Namik Kilinç, Bülent Şengül, Şükrü Beydemir

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Synthesis and biological evaluation of novel N9-heterobivalent β-carbolines as angiogenesis inhibitors by Liang Guo, Qin Ma, Wei Chen, Wenxi Fan, Jie Zhang, Bin Dai

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Coumarin-heterocycle framework: A privileged approach in promising anticancer drug design by Atukuri Dorababu

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Acridine Orange/exosomes increase the delivery and the effectiveness of Acridine Orange in human melanoma cells: A new prototype for theranostics of tumors by Elisabetta Iessi, Mariantonia Logozzi, Luana Lugini, Tommaso Azzarito, Cristina Federici, Enrico Pierluigi Spugnini, Davide Mizzoni, Rossella Di Raimo, Daniela F. Angelini, Luca Battistini, Serena Cecchetti, Stefano Fais

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Crystal structure-guided design of berberine-based novel chitinase inhibitors by Lei Chen, Ling Zhu, Jinli Chen, Wei Chen, Xuhong Qian, Qing Yang

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Discovery of a new class of triazole based inhibitors of acetyl transferase KAT2A by Roberta Pacifico, Nunzio Del Gaudio, Guglielmo Bove, Lucia Altucci, Lydia Siragusa, Gabriele Cruciani, Menotti Ruvo, Rosa Bellavita, Paolo Grieco, Mauro F. A. Adamo

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Synthesis, Molecular Docking and Anticancer Activity of Novel 1,3-Thiazolidin-4-Ones by Ramesh Sawant, Jyoti Wadekar, Rushikesh Ukirde, Ganesh Barkade

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In vitro inhibition of Mycobacterium tuberculosis β-carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos by Ashok Aspatwar, Milka Hammaren, Mataleena Parikka, Seppo Parkkila, Fabrizio Carta, Murat Bozdag, Daniela Vullo, Claudiu T. Supuran

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Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma by Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A

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Design, synthesis, and biological evaluation of novel ciprofloxacin derivatives as potential anticancer agents targeting topoisomerase II enzyme by Hadeer K. Swedan, Asmaa E. Kassab, Ehab M. Gedawy, Salwa E. Elmeligie

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Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 by Andrea Calcaterra, Valentina Iovine, Bruno Botta, Deborah Quaglio, Ilaria D'Acquarica, Alessia Ciogli, Antonia Iazzetti, Romina Alfonsi, Ludovica Lospinoso Severini, Paola Infante, Lucia Di Marcotullio, Mattia Mori, Francesca Ghirga

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Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect by Birte Arlt, Guido Mastrobuoni, Jasmin Wuenschel, Kathy Astrahantseff, Angelika Eggert, Stefan Kempa, Hedwig E. Deubzer

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Tumor necrosis factor alpha (TNFα)-binding imprinted polymers. A non-systemic therapeutic approach for inflammatory bowel diseases by Rina Arad Yellin, Anett Hudák, Tamás Letoha, Bernard S. Green

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Flavonoid-liposomes formulations: Physico-chemical characteristics, biological activities and therapeutic applications by Eleftherios G. Halevas, Dimitrios I. Avgoulas, George Katsipis, Anastasia A. Pantazaki

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Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform by Xianling Ning, Hailong Qi, Ridong Li, Yan Jin, Michael A. McNutt, Yuxin Yin

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