Search Results - "Medicinal Chemistry"

Synthesis, Characterization, Docking Study and Biological Activates of New 3-Aminorhodanine Derivatives by Noor Alhuda Dakel khalaf, Hiba Ali Hasan, Karima Fadhil Ali, Wesen Adel Mehdi

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Discovery of benzamide-hydroxypyridinone hybrids as potent multi-targeting agents for the treatment of Alzheimer's disease by Xiaoying Jiang, Jianan Guo, Changjun Zhang, Jinping Gu, Tao Zhou, Renren Bai, Yuanyuan Xie

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Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent by Cristina Campestre, Marcello Locatelli, Paolo Guglielmi, Elisa De Luca, Giuseppe Bellagamba, Sergio Menta, Gokhan Zengin, Christian Celia, Luisa Di Marzio, Simone Carradori

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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers by Jana Janockova, Jan Korabecny, Jana Plsikova, Katerina Babkova, Eva Konkolova, Dana Kucerova, Jana Vargova, Jan Koval, Rastislav Jendzelovsky, Peter Fedorocko, Jana Kasparkova, Viktor Brabec, Jan Rosocha, Ondrej Soukup, Slavka Hamulakova, Kamil Kuca, Maria Kozurkova

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Thiophene-Based Compounds with Potential Anti-Inflammatory Activity by Ryldene Marques Duarte da Cruz, Francisco Jaime Bezerra Mendonça-Junior, Natália Barbosa de Mélo, Luciana Scotti, Rodrigo Santos Aquino de Araújo, Reinaldo Nóbrega de Almeida, Ricardo Olímpio de Moura

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Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators by Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante

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sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease by Manuel González-Cuesta, Irene Herrera-González, M. Isabel García-Moreno, Roger A. Ashmus, David J. Vocadlo, José M. García Fernández, Eiji Nanba, Katsumi Higaki, Carmen Ortiz Mellet

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Insights into biological activity of ureidoamides with primaquine and amino acid moieties by Josipa Vlainić, Ivan Kosalec, Kristina Pavić, Dimitra Hadjipavlou-Litina, Eleni Pontiki, Branka Zorc

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Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors by Mona S. El-Zoghbi, Samiha A. El-Sebaey, Hanan A. AL-Ghulikah, Eman A. Sobh

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An In Silico Investigation of the Molecular Interactions between Volatile Anesthetics and Actin by Barbara Truglia, Nicola Carbone, Ibrahim Ghadre, Sara Vallero, Marinella Zito, Eric Adriano Zizzi, Marco Agostino Deriu, J. A. Tuszynski

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Aromatic sulphonamides of aziridine-2-carboxylic acid derivatives as novel PDIA1 and PDIA3 inhibitors by D. Zelencova-Gopejenko, V. Andrianov, I. Domracheva, I. Kanepe-Lapsa, M. Milczarek, M. Stojak, K. Przyborowski, F. A. Fedak, M. Walczak, K. Kramkowski, J. Wietrzyk, S. Chlopicki, I. Kalvins

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Discovery of natural anthraquinones as potent inhibitors against pancreatic lipase: structure-activity relationships and inhibitory mechanism by Zi-Qiang Chen, Wen-Yao He, Si-Yuan Yang, Hong-Hong Ma, Jing Zhou, Hao Li, Ya-Di Zhu, Xing-Kai Qian, Li-Wei Zou

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Synthesis, biological evaluation, and computational studies of N-benzyl pyridinium-curcumin derivatives as potent AChE inhibitors with antioxidant activity by Nafisah M. Al-Rifai, Nemeh M. Al-Khalileh, Jalal A. Zahra, Musa I. El-Barghouthi, Fouad H. Darras

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Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity by Mincheol Kwon, Sung-Kyun Ko, Mina Jang, Gun-Hee Kim, In-Ja Ryoo, Sangkeun Son, Hyung Won Ryu, Sei-Ryang Oh, Won-Kyu Lee, Bo Yeon Kim, Jae-Hyuk Jang, Jong Seog Ahn

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Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII by Tarfah Al-Warhi, Mostafa M. Elbadawi, Alessandro Bonardi, Alessio Nocentini, Ahmed A. Al-Karmalawy, Nada Aljaeed, Ohoud J. Alotaibi, Hatem A. Abdel-Aziz, Claudiu T. Supuran, Wagdy M. Eldehna

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Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives by Xiaole Chen, Min Gao, Rongchao Jian, Weiqian David Hong, Xiaowen Tang, Yuling Li, Denggao Zhao, Kun Zhang, Wenhua Chen, Xi Zheng, Zhaojun Sheng, Panpan Wu

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Activation of the β-carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with amines and amino acids by Andrea Angeli, Linda J. Urbański, Vesa P. Hytönen, Seppo Parkkila, Claudiu T. Supuran

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Antibacterial activity of 3-methylbenzo[d]thiazol-methylquinolinium derivatives and study of their action mechanism by Ning Sun, Ruo-Lan Du, Yuan-Yuan Zheng, Qi Guo, Sen-Yuan Cai, Zhi-Hua Liu, Zhi-Yuan Fang, Wen-Chang Yuan, Ting Liu, Xiao-Mei Li, Yu-Jing Lu, Kwok-Yin Wong

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Nitroaromatics as hypoxic cell radiosensitizers: A 2D-QSAR approach to explore structural features contributing to radiosensitization effectiveness by Priyanka De, Kunal Roy

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Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity by Satheesh Kumar Palanisamy, Daniela Trisciuoglio, Clemens Zwergel, Donatella Del Bufalo, Antonello Mai

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