Search Results - "Medicinal Chemistry"

Selectivity analyses of γ-benzylidene digoxin derivatives to different Na,K-ATPase α isoforms: a molecular docking approach by Marco T. C. Pessôa, Silmara L. G. Alves, Alex G. Taranto, José A. F. P. Villar, Gustavo Blanco, Leandro A. Barbosa

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An overview on the recently discovered iota-carbonic anhydrases by Alessio Nocentini, Claudiu T. Supuran, Clemente Capasso

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Academic Career Progression of Chinese-Origin Pharmacy Faculty Members in Western Countries by Weixiang Zhang, Hao Zhong, Yitao Wang, Ging Chan, Yuanjia Hu, Hao Hu, Defang Ouyang

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New benzothieno[2,3-c]pyridines as non-steroidal CYP17 inhibitors: design, synthesis, anticancer screening, apoptosis induction, and in silico ADME profile studies by Nadia A. Khalil, Eman M. Ahmed, Ashraf F. Zaher, Eman A. Sobh, Samiha A. El-Sebaey, Mona S. El-Zoghbi

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Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation by Chang-Ming Su, Gui-Ge Hou, Chun-Hua Wang, Hong-Qin Zhang, Cheng Yang, Mei Liu, Yun Hou

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Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones by Perihan A. Elzahhar, Rana A. Alaaeddine, Rasha Nassra, Azza Ismail, Hala F. Labib, Mohamed G. Temraz, Ahmed S. F. Belal, Ahmed F. El-Yazbi

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Genome mining of sulfonated lanthipeptides reveals unique cyclic peptide sulfotransferases by Meng Wang, Wen-Wei Li, Zhe Cao, Jianong Sun, Jiang Xiong, Si-Qin Tao, Tinghong Lv, Kun Gao, Shangwen Luo, Shi-Hui Dong

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Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease by Natalia Szałaj, Justyna Godyń, Jakub Jończyk, Anna Pasieka, Dawid Panek, Tomasz Wichur, Krzysztof Więckowski, Paula Zaręba, Marek Bajda, Anja Pislar, Barbara Malawska, Raimon Sabate, Anna Więckowska

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Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms by Melissa D'Ascenzio, Paolo Guglielmi, Simone Carradori, Daniela Secci, Rosalba Florio, Adriano Mollica, Mariangela Ceruso, Atilla Akdemir, Anatoly P. Sobolev, Claudiu T. Supuran

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Anti-breast cancer action of carbonic anhydrase IX inhibitor 4-[4-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzylidene-hydrazinocarbonyl]-benzenesulfonamide (BSM-0004): in vi... by Chandra Bhushan Mishra, Raj Kumar Mongre, Amresh Prakash, Raok Jeon, Claudiu T. Supuran, Myeong-Sok Lee

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Development of certain benzylidene coumarin derivatives as anti-prostate cancer agents targeting EGFR and PI3Kβ kinases by Lina M. A. Abdel Ghany, Tarek S. Ibrahim, Abdulrahman S. Alharbi, Mohamed S. Abdel-Aziz, Eman M. El-labbad, Mohamed Elagawany, Noha Ryad

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Design, synthesis and biological evaluation of edaravone derivatives bearing the N-benzyl pyridinium moiety as multifunctional anti-Alzheimer's agents by Luke S. Zondagh, Sarel F. Malan, Jacques Joubert

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Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors? by Claudiu T. Supuran

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New arylsparteine derivatives as positive inotropic drugs by Vito Boido, Marcella Ercoli, Michele Tonelli, Federica Novelli, Bruno Tasso, Fabio Sparatore, Elena Cichero, Paola Fossa, Paola Dorigo, Guglielmina Froldi

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Transition metal-catalysed A-ring C-H activations and C(sp2)-C(sp2) couplings in the 13α-oestrone series and in vitro evaluation of antiproliferative properties by Péter Traj, Ali Hazhmat Abdolkhaliq, Anett Németh, Sámuel Trisztán Dajcs, Ferenc Tömösi, Tea Lanisnik-Rizner, István Zupkó, Erzsébet Mernyák

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Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics by Ivani Pauli, Celso de O. Rezende Jr, Brian W. Slafer, Marco A. Dessoy, Mariana L. de Souza, Leonardo L. G. Ferreira, Abraham L. M. Adjanohun, Rafaela S. Ferreira, Luma G. Magalhães, Renata Krogh, Simone Michelan-Duarte, Ricardo Vaz Del Pintor, Fernando B. R. da Silva, Fabio C. Cruz, Luiz C. Dias, Adriano D. Andricopulo

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Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies by Ismail M. M. Othman, Mohamed A. M. Gad-Elkareem, Mohamed El-Naggar, Eman S. Nossier, Abd El-Galil E. Amr

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The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis by Juan Carlos García-Soriano, Héctor de Lucio, Daniel Elvira-Blázquez, Mercedes Alcón-Calderón, Natalia Sanz del Olmo, Pedro A. Sánchez-Murcia, Paula Ortega, Francisco Javier de la Mata, Antonio Jiménez-Ruiz

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Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as potent ALK-L1196M inhibitors by Yunju Nam, Dongkeun Hwang, Namdoo Kim, Hong-Seog Seo, Khalid B. Selim, Taebo Sim

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Glycoconjugates of Mucochloric Acid-Synthesis and Biological Activity by Katarzyna Żurawska, Daria Burdalska, Magdalena Skonieczna, Anna Byczek-Wyrostek, Anahit Dawicka, Anna Kasprzycka, Krzysztof Walczak

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