Search Results - "Medicinal Chemistry"

Promising inhibition of diabetes-related enzymes and antioxidant properties of Ptilostemon casabonae leaves extract by Cinzia Sanna, Antonella Fais, Benedetta Era, Giovanna L. Delogu, Enrico Sanna, Laura Dazzi, Antonella Rosa, Arianna Marengo, Patrizia Rubiolo, Antonio De Agostini, Sonia Floris, Francesca Pintus

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Synthesis, characterization and in vitro inhibition of metal complexes of pyrazole based sulfonamide on human erythrocyte carbonic anhydrase isozymes I and II by Nurgün Büyükkıdan, Bülent Büyükkıdan, Metin Bülbül, Rahmi Kasımoğulları, Samet Mert

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Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFRWT and EGFRT790M inhibitors by Tarfah Al-Warhi, Ahmed A. Al-Karmalawy, Ayman Abo Elmaaty, Maha A. Alshubramy, Marwa Abdel-Motaal, Taghreed A. Majrashi, Medhat Asem, Ahmed Nabil, Wagdy M. Eldehna, Marwa Sharaky

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Estrogen Receptor-α Targeting: PROTACs, SNIPERs, Peptide-PROTACs, Antibody Conjugated PROTACs and SNIPERs by Arvind Negi, Kavindra Kumar Kesari, Anne Sophie Voisin-Chiret

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Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies by Mohamed M. Khalifa, Ahmed A. Al-Karmalawy, Eslam B. Elkaeed, Mohamed S. Nafie, Mohamed A. Tantawy, Ibrahim H. Eissa, Hazem A. Mahdy

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Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series by Ashok Aspatwar, Nanda Kumar Parvathaneni, Harlan Barker, Emilie Anduran, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Seppo Parkkila, Jean-Yves Winum

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A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities by C Geethapriya Loganathan, Karthickeyan Krishnan, S D Vachala, Deeparani Urolagin, J Vijayakumar

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Opportunities, obstacles and current challenges of flavonoids for luminal and triple-negative breast cancer therapy by Vanina S. Vachetta, Mariel Marder, María F. Troncoso, María T. Elola

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pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models by Federica Rinaldi, Elena Del Favero, Valeria Rondelli, Stefano Pieretti, Alessia Bogni, Jessica Ponti, François Rossi, Luisa Di Marzio, Donatella Paolino, Carlotta Marianecci, Maria Carafa

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In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies of substituted 1,2,4-oxadiazole analogues against Mycobacterium tuberculosis by Pran Kishore Deb, Nizar A. Al-Shar'i, Katharigatta N. Venugopala, Melendhran Pillay, Pobitra Borah

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Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer's disease by Hongtao Du, Jinzhi Song, Fang Ma, Hongxin Gao, Xinyan Zhao, Renjun Mao, Xiaolong He, Yan Yan

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Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents by Kangjia Du, Wantong Ma, Chengjie Yang, Zhongkun Zhou, Shujian Hu, Yanan Tian, Hao Zhang, Yunhao Ma, Xinrong Jiang, Hongmei Zhu, Huanxiang Liu, Peng Chen, Yingqian Liu

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Requiem for Rimonabant: Therapeutic Potential for Cannabinoid CB₁ Receptor Antagonists after the Fall by Taryn Bosquez-Berger, Gergő Szanda, Alex Straiker

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Synthesis, antimicrobial, anti-biofilm evaluation, and molecular modelling study of new chalcone linked amines derivatives by Shahenda M. El-Messery, El-Sayed E. Habib, Sarah T. A. Al-Rashood, Ghada S. Hassan

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Structure-activity relationship investigation of tertiary amine derivatives of cinnamic acid as acetylcholinesterase and butyrylcholinesterase inhibitors: compared with that of phe... by Xiaohui Gao, Jingjing Tang, Haoran Liu, Linbo Liu, Lu Kang, Wen Chen

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Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy by Mykhaylo Dukh, Joseph Cacaccio, Farukh A. Durrani, Ishaan Kumar, Ramona Watson, Walter A. Tabaczynski, Penny Joshi, Joseph R. Missert, Heinz Baumann, Ravindra K. Pandey

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Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science by Émile Breault, Michael Desgagné, Jolien De Neve, Jérôme Côté, Thomas M.A. Barlow, Steven Ballet, Philippe Sarret

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Design, synthesis, and biological activity evaluation of dihydromyricetin derivatives against SARS-CoV-2-Omicron virus by Cong Wu, Qi Jiang, Hui Zhong, Xudong Zhou, Leping Liu, Tong Pan, Chao Liu, Wei Wang, Wenbing Sheng

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Design, synthesis, biological evaluation and QSAR analysis of novel N-substituted benzimidazole derived carboxamides by Anja Beč, Marija Mioč, Branimir Bertoša, Marija Kos, Patricia Debogović, Marijeta Kralj, Kristina Starčević, Marijana Hranjec

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The Role of Organosulfur Compounds as Nrf2 Activators and Their Antioxidant Effects by Melford Chuka Egbujor, Maria Petrosino, Karim Zuhra, Luciano Saso

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