Search Results - "Medicinal Chemistry"

(Iso)quinoline amides derived from corosolic acid exhibit high cytotoxicity, and the potential for overcoming drug resistance in human cancer cells by Niels V. Heise, René Csuk, Thomas Mueller

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The translocator protein ligands as mitochondrial functional modulators for the potential anti-Alzheimer agents by TaeHun Kim, Mohammad N. Morshed, Ashwini M. Londhe, Ji W. Lim, Ha E. Lee, Suengmok Cho, Sung J. Cho, Hayoung Hwang, Sang M. Lim, Jae Y. Lee, Jiyoun Lee, Ae N. Pae

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Synthesis and in vitro evaluation of benzo[b]thiophene-3-carboxylic acid 1,1-dioxide derivatives as anticancer agents targeting the RhoA/ROCK pathway by Jinhao Liang, Jin Huang, Jianzhan Yang, Weihong Liang, Haoxiang Li, Yunshan Wu, Bo Liu

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Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives by Francesco Saccoliti, Gabriella Angiulli, Giovanni Pupo, Luca Pescatori, Valentina Noemi Madia, Antonella Messore, Gianni Colotti, Annarita Fiorillo, Luigi Scipione, Marina Gramiccia, Trentina Di Muccio, Roberto Di Santo, Roberta Costi, Andrea Ilari

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Design, synthesis, and biological evaluation of (thio)urea derivatives as potent Escherichia coli β-glucuronidase inhibitors by Keren Xu, Leyi Ying, Titi Ying, Qihao Wu, Lin Du, Yanlei Yu, Youmin Ying, Bin Wei, Hong Wang, Zhikun Yang

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Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication by Jenny Kouretova, M. Zouhir Hammamy, Anton Epp, Kornelia Hardes, Stephanie Kallis, Linlin Zhang, Rolf Hilgenfeld, Ralf Bartenschlager, Torsten Steinmetzer

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MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction by Le Zhang, Lei Zhang, Yue Guo, Ming Xiao, Lu Feng, Chengcan Yang, Guan Wang, Liang Ouyang

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Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides by Dilek Canakci, Ismail Koyuncu, Nabih Lolak, Mustafa Durgun, Suleyman Akocak, Claudiu T. Supuran

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The current state of bioterrorist attack surveillance and preparedness in the US by Grundmann O

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Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy by Youssef Dgachi, Hélène Martin, Rim Malek, Daniel Jun, Jana Janockova, Vendula Sepsova, Ondrej Soukup, Isabel Iriepa, Ignacio Moraleda, Emna Maalej, M. Carmo Carreiras, Bernard Refouvelet, Fakher Chabchoub, José Marco-Contelles, Lhassane Ismaili

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Design, synthesis, in vitro and in vivo biological evaluation of pterostilbene derivatives for anti-inflammation therapy by Liuzeng Chen, Ke Wang, Xiaohan Liu, Lifan Wang, Hui Zou, Shuying Hu, Lingling Zhou, Rong Li, Shiying Cao, Banfeng Ruan, Quanren Cui

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Dual-target ligand discovery for Alzheimer's disease: triphenylphosphoranylidene derivatives as inhibitors of acetylcholinesterase and β-amyloid aggregation by Marwa El-Hussieny, Mansoura A. Abd-, Fouad M. Soliman, Marwa A. Fouad, Mohamed K. El-Ashrey

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Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity by Amr Sonousi, Rasha A. Hassan, Eman O. Osman, Amr M. Abdou, Soha H. Emam

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Using 5-Nitroimidazole Derivatives against Neglected Tropical Protozoan Diseases: Systematic Review by Micheel M. Vichi-Ramírez, Edgar López-López, Catalina Soriano-Correa, Carolina Barrientos-Salcedo

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Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: synthesis, characterisation and biological evaluation by Jeremie Brichet, Rodrigo Arancibia, Emanuela Berrino, Claudiu T. Supuran

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Discovery of novel mRNA demethylase FTO inhibitors against esophageal cancer by Bo Qin, Qian Bai, Dan Yan, Fanxiang Yin, Zhu Zhu, Chaoyuan Xia, Yang Yang, Yi Zhao

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Synthesis and characterisation of (Z)-styrylbenzene derivatives as potential selective anticancer agents by Ya-Bing Xin, Jia-Jun Li, Hong-Jian Zhang, Jun Ma, Xin Liu, Guo-Hua Gong, Yu-Shun Tian

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Benzenesulfonamides with different rigidity-conferring linkers as carbonic anhydrase inhibitors: an insight into the antiproliferative effect on glioblastoma, pancreatic, and breas... by Francesco Liguori, Simone Carradori, Roberto Ronca, Sara Rezzola, Serena Filiberti, Fabrizio Carta, Marta Turati, Claudiu T. Supuran

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Inhibitory evaluation of Curculigo latifolia on α-glucosidase, DPP (IV) and in vitro studies in antidiabetic with molecular docking relevance to type 2 diabetes mellitus by Nur Athirah Zabidi, Nur Akmal Ishak, Muhajir Hamid, Siti Efliza Ashari, Muhammad Alif Mohammad Latif

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Production, purification and biochemical characterisation of a novel lipase from a newly identified lipolytic bacterium Staphylococcus caprae NCU S6 by Junxin Zhao, Maomao Ma, Zheling Zeng, Ping Yu, Deming Gong, Shuguang Deng

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