Search Results - "Medicinal Chemistry"

Inhibition of <i>Staphylococcus pseudintermedius</i> Efflux Pumps by Using <i>Staphylococcus aureus</i> NorA Efflux Pump Inhibitors by Elisa Rampacci, Tommaso Felicetti, Giada Cernicchi, Valentina Stefanetti, Stefano Sabatini, Fabrizio Passamonti

Connect to this object online.

Anticancer effect of new cyclocoumarol derivatives by Racha Karaky, Joumana Al-Akhdar, Fatima Saab, Batoul Rostom, Wassim Shebaby, Mohamed Mroueh, Mona Diab-Assaf, Issam Kassab, Maité Sylla-Iyarreta Veitia

Connect to this object online.

Discovery of new symmetrical and asymmetrical nitrile-containing 1,4-dihydropyridine derivatives as dual kinases and P-glycoprotein inhibitors: synthesis, in vitro assays, and in s... by Mohamed H. Saad, Tarek F. El-Moselhy, Nabaweya S, El-Din, Ahmed B. M. Mehany, Amany Belal, Mohammed A. S. Abourehab, Haytham O. Tawfik, Mervat H. El-Hamamsy

Connect to this object online.

Design, synthesis and biological evaluation of 4-bromo-N-(3,5-dimethoxyphenyl)benzamide derivatives as novel FGFR1 inhibitors for treatment of non-small cell lung cancer by Zixin Xie, Donghua Cheng, Lu Luo, Guoliang Shen, Suwei Pan, Yaqian Pan, Bo Chen, Xuebao Wang, Zhiguo Liu, Yuan Zhang, Faqing Ye

Connect to this object online.

Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation by Jonathan Elie, Omid Feizbakhsh, Nathalie Desban, Béatrice Josselin, Blandine Baratte, Amandine Bescond, Julien Duez, Xavier Fant, Stéphane Bach, Dominique Marie, Matthieu Place, Sami Ben Salah, Agnes Chartier, Sabine Berteina-Raboin, Apirat Chaikuad, Stefan Knapp, Fabrice Carles, Pascal Bonnet, Frédéric Buron, Sylvain Routier, Sandrine Ruchaud

Connect to this object online.

Rational design of biodegradable sulphonamide candidates treating septicaemia by synergistic dual inhibition of COX-2/PGE2 axis and DHPS enzyme by Nada H. El-Dershaby, Soad A. El-Hawash, Shaymaa E. Kassab, Hoda G. Dabees, Ahmed E. Abdel Moneim, Ibrahim A. Abdel Wahab, Mohammad M. Abd-Alhaseeb, Mostafa M. M. El-Miligy

Connect to this object online.

The first activation study of a δ-carbonic anhydrase: TweCAδ from the diatom Thalassiosira weissflogii is effectively activated by amines and amino acids by Andrea Angeli, Fatmah A. S. Alasmary, Sonia Del Prete, Sameh M. Osman, Zeid AlOthman, William A. Donald, Clemente Capasso, Claudiu T. Supuran

Connect to this object online.

Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agent... by Alessandro Deplano, Jessica Karlsson, Federica Moraca, Mona Svensson, Claudia Cristiano, Carmine Marco Morgillo, Christopher J. Fowler, Roberto Russo, Bruno Catalanotti, Valentina Onnis

Connect to this object online.

Plasmatic exosomes from prostate cancer patients show increased carbonic anhydrase IX expression and activity and low pH by Mariantonia Logozzi, Davide Mizzoni, Clemente Capasso, Sonia Del Prete, Rossella Di Raimo, Mario Falchi, Daniela F. Angelini, Alessandro Sciarra, Martina Maggi, Claudiu T. Supuran, Stefano Fais

Connect to this object online.

Epigallocatechin-3-gallate at the nanoscale: a new strategy for cancer treatment by Wenxue Sun, Yizhuang Yang, Cuiyun Wang, Mengmeng Liu, Jianhua Wang, Sen Qiao, Pei Jiang, Changgang Sun, Shulong Jiang

Connect to this object online.

Therapeutic potential of natural alkaloid emetine against emerging COVID-19 and future viral pandemics by Biswanath Dinda, Subhajit Dinda, Manikarna Dinda, Indrajit Sil Sarma, Santanu Majumdar, Shekhar Saha

Connect to this object online.

Synthesis, kinetic studies and in-silico investigations of novel quinolinyl-iminothiazolines as alkaline phosphatase inhibitors by Muhammad Naeem Mustafa, Pervaiz Ali Channar, Muhammad Sarfraz, Aamer Saeed, Syeda Abida Ejaz, Mubashir Aziz, Fatmah Ali Alasmary, Hanadi Yaqob Alsoqair, Hussain Raza, Song Ja Kim, Asad Hamad

Connect to this object online.

Target-based drug discovery through inversion of quantitative structure-drug-property relationships and molecular simulation: CA IX-sulphonamide complexes by Petar Žuvela, J. Jay Liu, Myunggi Yi, Paweł P. Pomastowski, Gulyaim Sagandykova, Mariusz Belka, Jonathan David, Tomasz Bączek, Krzysztof Szafrański, Beata Żołnowska, Jarosław Sławiński, Claudiu T. Supuran, Ming Wah Wong, Bogusław Buszewski

Connect to this object online.

Novel pyrazolo[3,4-d]pyrimidines: design, synthesis, anticancer activity, dual EGFR/ErbB2 receptor tyrosine kinases inhibitory activity, effects on cell cycle profile and caspase-3... by Mai Maher, Asmaa E. Kassab, Ashraf F. Zaher, Zeinab Mahmoud

Connect to this object online.

Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect by Tarek S. Ibrahim, Mohamed M. Hawwas, Azizah M. Malebari, Ehab S. Taher, Abdelsattar M. Omar, Thikryat Neamatallah, Zakaria K. Abdel-Samii, Martin K. Safo, Yaseen A. M. M. Elshaier

Connect to this object online.

Anticancer properties and mechanism of action of the fungal nucleoside clitocine and its derivatives by Christian Bailly

Connect to this object online.

Semisynthesis and anti-cancer properties of novel honokiol derivatives in human nasopharyngeal carcinoma CNE-2Z cells by Bo-Han Li, Hui Ma, Jing Zhu, Jie Chen, Yi-Qun Dai, Xiao-Jing Zhang, Hong-Mei Li, Cheng-Zhu Wu

Connect to this object online.

Design, synthesis and evaluation of 18F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging by Zhengxing Zhang, Joseph Lau, Chengcheng Zhang, Nadine Colpo, Alessio Nocentini, Claudiu T. Supuran, François Bénard, Kuo-Shyan Lin

Connect to this object online.

Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents by Sudong Liang, Yifei Geng, Miao-Miao Niu, Yan Zhang, Weiping He, Jindong Li, Li Yang, Zhen Xu

Connect to this object online.

Design, synthesis, and analysis of antiproliferative and apoptosis-inducing activities of nitrile derivatives containing a benzofuran scaffold: EGFR inhibition assay and molecular... by Salma Fares, Khalid B. Selim, Fatma E. Goda, Magda A. A. El-Sayed, Nawaf A. AlSaif, Mohamed M. Hefnawy, Alaa A.-M, Adel S. El-Azab

Connect to this object online.