Search Results - "Medicinal Chemistry"

Phytochemical profile, enzyme inhibition activity and molecular docking analysis of Feijoa sellowiana O. Berg by Fatema R. Saber, Rehab M. Ashour, Ali M. El-Halawany, Mohamad Fawzi Mahomoodally, Gunes Ak, Gokhan Zengin, Engy A. Mahrous

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Design, synthesis and SAR studies of novel tacrine derivatives as potent cholinesterase inhibitors by Bhushanarao Dogga, Eeda Koti Reddy, C.S. Sharanya, J. Abhithaj, K.G. Arun, C.S. Ananda Kumar, K.S. Rangappa

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Design, synthesis and antimalarial activity of novel bis{N-[(pyrrolo[1,2-a]quinoxalin-4-yl)benzyl]-3-aminopropyl}amine derivatives by Jean Guillon, Anita Cohen, Nassima Meriem Gueddouda, Rabindra Nath Das, Stéphane Moreau, Luisa Ronga, Solène Savrimoutou, Louise Basmaciyan, Alix Monnier, Myriam Monget, Sandra Rubio, Timothée Garnerin, Nadine Azas, Jean-Louis Mergny, Catherine Mullié, Pascal Sonnet

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Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones by Sinan Bilginer, Halise Inci Gul, Feyza Sena Erdal, Hiroshi Sakagami, Serkan Levent, Ilhami Gulcin, Claudiu T. Supuran

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In vitro Biological Evaluation of 1,2,4-triazole Mannich Base by Mahmood Sherzad Rafaat, Arzu Karatepe, Serhat Keser, Şule İnci, Semih Dalkılıc

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Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease by Donia E. Hafez, Mariam Dubiel, Gabriella La Spada, Marco Catto, David Reiner-Link, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Holger Stark, Ashraf H. Abadi

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Some natural compounds and their analogues having potent anti- SARS-CoV-2 and anti-proteases activities as lead molecules in drug discovery for COVID-19 by Biswanath Dinda, Manikarna Dinda, Subhajit Dinda, Mithun Chakraborty

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Non-small cell lung cancer sensitisation to platinum chemotherapy via new thiazole-triazole hybrids acting as dual T-type CCB/MMP-9 inhibitors by Hassan Gamal, Khadiga A. Ismail, A-Mohsen M. E. Omar, Mohamed Teleb, Marwa M. Abu-Serie, Sun Huang, Abdalla S. Abdelsattar, Gerald W. Zamponi, Hesham Fahmy

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Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breas... by Marwa Sharaky, Marwa Kamel, Marwa A. Aziz, Mervat Omran, Monira M. Rageh, Khaled A. M. Abouzid, Samia A. Shouman

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Novel 1,2,3-triazole-aurone hybrids as cathepsin B inhibitors: One-pot synthesis, anti-proliferative, and drug modeling studies by Bhavna Saroha, Gourav Kumar, Suresh Kumar, Meena Kumari, Manishita Rani, Neera Raghav, Pranab Kumar Sahoo, Sushmita Ghosh, Sutapa Mahata, Vilas D. Nasare

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Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening by Albertus Eka Yudistira Sarwono, Shinya Mitsuhashi, Mohammad Hazzaz Bin Kabir, Kengo Shigetomi, Tadashi Okada, Fumina Ohsaka, Satoko Otsuguro, Katsumi Maenaka, Makoto Igarashi, Kentaro Kato, Makoto Ubukata

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Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro by Hongbo Liu, Fei Ye, Qi Sun, Hao Liang, Chunmei Li, Siyang Li, Roujian Lu, Baoying Huang, Wenjie Tan, Luhua Lai

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Sulfonamide inhibition studies of two β-carbonic anhydrases from the ascomycete fungus Sordaria macrospora, CAS1 and CAS2 by Daniela Vullo, Ronny Lehneck, Stefanie Pöggeler, Claudiu T. Supuran

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Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3) by Jinyun Dong, Jing Yang, Wenkai Yu, Haobin Li, Maohua Cai, Jing-Li Xu, Han-Dong Xu, Yun-Fu Shi, Xiaoqing Guan, Xiang‑Dong Cheng, Jiang‑Jiang Qin

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One-pot three-component synthesis of novel spirooxindoles with potential cytotoxic activity against triple-negative breast cancer MDA-MB-231 cells by Wagdy M. Eldehna, Dina H. EL-Naggar, Ahmed R. Hamed, Hany S. Ibrahim, Hazem A. Ghabbour, Hatem A. Abdel-Aziz

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Exploration of multitargeted antialzheimer's activity of safflower leaves phytoconstituents: In silico molecular docking approach by Dolly Das, Monali Nanda, Purusottam Banjare, Sweety Lanjhiyana

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Heterologous expression and biochemical characterisation of the recombinant β-carbonic anhydrase (MpaCA) from the warm-blooded vertebrate pathogen malassezia pachydermatis by Viviana De Luca, Andrea Angeli, Valeria Mazzone, Claudia Adelfio, Vincenzo Carginale, Andrea Scaloni, Fabrizio Carta, Silvia Selleri, Claudiu T. Supuran, Clemente Capasso

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Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu, Min-Wu Chao, Cheng-Chung Lee, Chao-Shiang Peng, Yi-Wen Wu, Tony Eight Lin, Yu-Wei Chang, Shih-Chung Yen, Kai-Cheng Hsu, Shiow-Lin Pan, Wei-Chun HuangFu

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Tricyclic coumarin sulphonate derivatives with alkaline phosphatase inhibitory effects: in vitro and docking studies by Jamshed Iqbal, Mohammed I. El-Gamal, Syeda Abida Ejaz, Joanna Lecka, Jean Sévigny, Chang-Hyun Oh

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Identifying HSV-1 Inhibitors from Natural Compounds via Virtual Screening Targeting Surface Glycoprotein D by Jiadai Wu, Helen Power, Monica Miranda-Saksena, Peter Valtchev, Aaron Schindeler, Anthony L. Cunningham, Fariba Dehghani

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