Search Results - "Medicinal Chemistry"

Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket by Koffi N'Guessan Placide Gabin Allangba, Mélalie Keita, Raymond Kre N'Guessan, Eugene Megnassan, Vladimir Frecer, Stanislav Miertus

Connect to this object online.

Synthesis and characterization of a glycine- modified heptamethine indocyanine dye for in vivo cancer-targeted near-infrared imaging by Liu T, Luo S, Wang Y, Tan X, Qi Q, Shi C

Connect to this object online.

Comparison of the amine/amino acid activation profiles of the β- and γ-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei by Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Fatmah A. S. Alasmary, Zeid AlOthman, William A. Donald, Clemente Capasso, Claudiu T. Supuran

Connect to this object online.

Activation studies of the β-carbonic anhydrases from Escherichia coli with amino acids and amines by Alessio Nocentini, Sonia Del Prete, Margaret D. Mastrolorenzo, William A. Donald, Clemente Capasso, Claudiu T. Supuran

Connect to this object online.

A study of Rose Bengal against a 2-keto-3-deoxy-d-manno-octulosonate cytidylyltransferase as an antibiotic candidate by Suwon Kim, Seri Jo, Mi-Sun Kim, Dong Hae Shin

Connect to this object online.

Antiviral Peptide-Based Conjugates: State of the Art and Future Perspectives by Toni Todorovski, Daniela Kalafatovic, David Andreu

Connect to this object online.

Prospecting in silico antibacterial activity of a peptide from trypsin inhibitor isolated from tamarind seed by Gerciane Silva de Oliveira, Amanda Maria de Souza Nascimento, Anna Beatriz Santana Luz, Ana Júlia Felipe Camelo Aguiar, Mayara Santa Rosa Lima, Lídia Leonize Rodrigues Matias, Isabel Rodríguez Amado, Thais Souza Passos, Karla Suzane Florentino da Silva Chaves Damasceno, Norberto de Kássio Vieira Monteiro, Susana Margarida Gomes Moreira, Lorenzo Pastrana, Ana Heloneida de Araújo Morais

Connect to this object online.

Anti inflammatory properties and safety of green synthesized metal and metal oxide nanoparticles: A review article by Ream Nayal, Diana Mejjo, Mohammad Yaser Abajy

Connect to this object online.

GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori by Rawah H. Elkousy, Nada M. Mostafa, Ahmed M. Abd-alkhalek, Mahmoud A. El Hassab, Sara T. Al-Rashood, Wagdy M. Eldehna, Omayma A. Eldahshan

Connect to this object online.

Chalcone: A potential scaffold for NLRP3 inflammasome inhibitors by Pritam Thapa, Sunil P. Upadhyay, Vikas Singh, Varun C. Boinpelly, Jianping Zhou, David K. Johnson, Prajwal Gurung, Eung Seok Lee, Ram Sharma, Mukut Sharma

Connect to this object online.

Computational screening of chalcones acting against topoisomerase IIα and their cytotoxicity towards cancer cell lines by Kanyani Sangpheak, Monika Mueller, Nitchakan Darai, Peter Wolschann, Chonticha Suwattanasophon, Ritbey Ruga, Warinthon Chavasiri, Supaporn Seetaha, Kiattawee Choowongkomon, Nawee Kungwan, Chompoonut Rungnim, Thanyada Rungrotmongkol

Connect to this object online.

Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II by Jekaterīna Ivanova, Morteza Abdoli, Alessio Nocentini, Raivis Žalubovskis, Claudiu T. Supuran

Connect to this object online.

Discovery of new nicotinamides as apoptotic VEGFR-2 inhibitors: virtual screening, synthesis, anti-proliferative, immunomodulatory, ADMET, toxicity, and molecular dynamic simulatio... by Reda G. Yousef, Albaraa Ibrahim, Mohamed M. Khalifa, Wagdy M. Eldehna, Ibraheem M. M. Gobaara, Ahmed B. M. Mehany, Eslam B. Elkaeed, Aisha A. Alsfouk, Ahmed M. Metwaly, Ibrahim H. Eissa

Connect to this object online.

Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison by Ulviye Acar Çevik, Begüm Nurpelin Sağlık, Derya Osmaniye, Serkan Levent, Betül Kaya Çavuşoğlu, Abdullah Burak Karaduman, Özlem Atlı Eklioğlu, Yusuf Özkay, Zafer Asım Kaplancıklı

Connect to this object online.

Discovery of N-aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents in vitro and in vivo via activating the Hippo signalling pathway by Jin-Bo Niu, Chun-Hua Quan, Yuan Liu, Guang-Xi Yu, Jia-Jia Yang, Yin-Ru Li, Yan-Bing Zhang, Ying-Qiu Qi, Jian Song, Cheng-Yun Jin, Sai-Yang Zhang

Connect to this object online.

Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer's disease by Chuanyu Yu, Xueyan Liu, Bingxiang Ma, Jiexin Xu, Yiquan Chen, Chaoxian Dai, Huaping Peng, Daijun Zha

Connect to this object online.

Recruitment of hexahydroquinoline as anticancer scaffold targeting inhibition of wild and mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R) by Mahmoud G. Abo Al-Hamd, Haytham O. Tawfik, Omeima Abdullah, Koki Yamaguchi, Masaharu Sugiura, Ahmed B. M. Mehany, Mervat H. El-Hamamsy, Tarek F. El-Moselhy

Connect to this object online.

Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors by Adriana M. das Neves, Gabriele A. Berwaldt, Cinara T. Avila, Taís B. Goulart, Bruna C. Moreira, Taís P. Ferreira, Mayara S. P. Soares, Nathalia S. Pedra, Luiza Spohr, Anita A. A. dE Souza, Roselia M. Spanevello, Wilson Cunico

Connect to this object online.

Development of new thiazolidine-2,4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: design, synthesis, biological investigations, and in sili... by Abdelrahman Hamdi, Muhammad Yaseen, Wafaa A. Ewes, Mashooq Ahmad Bhat, Noha I. Ziedan, Hamed W. El-Shafey, Ahmed A. B. Mohamed, Mohamed R. Elnagar, Abdullah Haikal, Dina I. A. Othman, Abdullah A. Elgazar, Ahmed H. A. Abusabaa, Kamal S. Abdelrahman, Osama M. Soltan, Mostafa M. Elbadawi

Connect to this object online.

Discovery and evaluation of novel synthetic 5-alkyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-1-carbox-amide derivatives as anti-inflammatory agents by Qing-Kun Shen, Guo-Hua Gong, Gao- Li, Mei- Jin, Li-Hua Cao, Zhe-Shan Quan

Connect to this object online.