Search Results - "Medicinal Chemistry"

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking s... by Alaa A.-M, Adel S. El-Azab, Nawaf A. AlSaif, Ahmad J. Obaidullah, Abdulrahman M. Al-Obaid, Ibrahim A. Al-Suwaidan

Connect to this object online.

Synthesis of Some 1, 3, 4- Oxadizole Derivatives from Naproxen and Acetyl Chloride by Alya A. Dawood

Connect to this object online.

Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities by Chao Wang, Yujing Zhang, Shanbo Yang, Lingyu Shi, Rong Rong, Tingting Zhang, Yudong Wu, Dongming Xing

Connect to this object online.

Overcoming the imatinib-resistant BCR-ABL mutants with new ureidobenzothiazole chemotypes endowed with potent and broad-spectrum anticancer activity by Ashraf K. El-Damasy, Heewon Jin, Jung Woo Park, Hyun Ji Kim, Hanan Khojah, Seon Hee Seo, Ju-Hyeon Lee, Eun-Kyoung Bang, Gyochang Keum

Connect to this object online.

Cloning, expression, and purification of an α-carbonic anhydrase from Toxoplasma gondii to unveil its kinetic parameters and anion inhibition profile. by Viviana De Luca, Simone Giovannuzzi, Clemente Capasso, Claudiu T. Supuran

Connect to this object online.

Synthesis and evaluation of 2,4,5-trisubstitutedthiazoles as carbonic anhydrase-III inhibitors by Bilal A. Al-Jaidi, Pran Kishore Deb, Soha Taher Telfah, Abdel Naser Dakkah, Yazan A. Bataineh, Qutaiba Ahmed Al Khames Aga, Mohammad A. Al-dhoun, Ala' Ali Ahmad Al-Subeihi, Haifa'a Marouf Odetallah, Sanaa K. Bardaweel, Raghuprasad Mailavaram, Katharigatta N. Venugopala, Anroop B. Nair

Connect to this object online.

The mechanism and pharmacodynamics of 2-((1H-indol-3-yl)thio/sulfinyl)-N-pheny acetamide derivative as a novel inhibitor against human respiratory syncytial virus by Ningning Cheng, Nan Jiang, Yuanhui Fu, Zhuxin Xu, Xianglei Peng, Jiemei Yu, Shan Cen, Yucheng Wang, Guoning Zhang, Yanpeng Zheng, Jinsheng He

Connect to this object online.

Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma by Shaymaa E. Kassab, Samar Mowafy, Aya M. Alserw, Joustin A. Seliem, Shahenda M. El-Naggar, Nesreen N. Omar, Mohamed M. Awad

Connect to this object online.

Design, Synthesis, and Characterization of Novel Coordination Compounds of Benzimidazole Derivatives with Cadmium by Anita Raducka, Marcin Świątkowski, Izabela Korona-Głowniak, Barbara Kaproń, Tomasz Plech, Małgorzata Szczesio, Katarzyna Gobis, Agnieszka Czylkowska

Connect to this object online.

Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibi... by Lina M. A. Abdel Ghany, Botros Y. Beshay, Amal M. Youssef Moustafa, Ali Hassan Ahmed Maghrabi, Eman Hussain Khalifa Ali, Rasha Mohammed Saleem, Islam Zaki, Noha Ryad

Connect to this object online.

Exploring the therapeutic potential of xanthones in diabetes management: Current insights and future directions by Riya Saikia, Kalyani Pathak, Pallab Pramanik, Md Ariful Islam, Shreyasi Karmakar, Saptasikha Gogoi, Manash Pratim Pathak, Dibyajyoti Das, Jon Jyoti Sahariah, Mohammad Zaki Ahmad, Aparoop Das

Connect to this object online.

Synthesis, physiochemical property and antimicrobial activity of novel quaternary ammonium salts by Xianrui Xie, Wei Cong, Feng Zhao, Hongjuan Li, Wenyu Xin, Guige Hou, Chunhua Wang

Connect to this object online.

Discovery of new thymol-3,4-disubstituted thiazole hybrids as dual COX-2/5-LOX inhibitors with in vivo proof by Mostafa M. M. El-Miligy, Ahmed K. Al-Kubeisi, Rasha A. Nassra, Saad R. El-Zemity, Aly A. Hazzaa

Connect to this object online.

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation by Mohamed A. Abdelrahman, Wagdy M. Eldehna, Alessio Nocentini, Hany S. Ibrahim, Hadia Almahli, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri, Claudiu T. Supuran

Connect to this object online.

Cloning, expression and purification of the α-carbonic anhydrase from the mantle of the Mediterranean mussel, Mytilus galloprovincialis by Rosa Perfetto, Sonia Del Prete, Daniela Vullo, Vincenzo Carginale, Giovanni Sansone, Carmela M. A. Barone, Mosè Rossi, Fatmah A. S. Alasmary, Sameh M. Osman, Zeid AlOthman, Claudiu T. Supuran, Clemente Capasso

Connect to this object online.

Redox Active Molecules in Cancer Treatments

DOAB: download the publication
DOAB: description of the publication

Cancer stem cells CD133 inhibition and cytotoxicity of certain 3-phenylthiazolo[3,2-a]benzimidazoles: design, direct synthesis, crystal study and in vitro biological evaluation by Ghada H. Al-Ansary, Wagdy M. Eldehna, Hazem A. Ghabbour, Sara T. A. Al-Rashood, Khalid A. Al-Rashood, Radwa A. Eladwy, Abdullah Al-Dhfyan, Maha M. Kabil, Hatem A. Abdel-Aziz

Connect to this object online.

Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers by Heba S. A. Elzahabi, Eman S. Nossier, Rania A. Alasfoury, May El-Manawaty, Sara M. Sayed, Eslam B. Elkaeed, Ahmed M. Metwaly, Mohamed Hagras, Ibrahim H. Eissa

Connect to this object online.

Design and green synthesis of novel quinolinone derivatives of potential anti-breast cancer activity against MCF-7 cell line targeting multi-receptor tyrosine kinases by Mohamed Mokhtar, Khadijah S. Alghamdi, Nesreen S. Ahmed, Dina Bakhotmah, Tamer S. Saleh

Connect to this object online.

Synthesis, anticancer and apoptosis-inducing activities of quinazoline-isatin conjugates: epidermal growth factor receptor-tyrosine kinase assay and molecular docking studies by Adel S. El-Azab, Abdullah Al-Dhfyan, Alaa A.-M, Laila A. Abou-Zeid, Hamad M. Alkahtani, Abdulrahman M. Al-Obaid, Manal A. Al-Gendy

Connect to this object online.