Search Results - "Medicinal Chemistry"

Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors by Xu-Yang Deng, Jun-Jie Ke, Ying-Ying Zheng, Dong-Li Li, Kun Zhang, Xi Zheng, Jing-Ying Wu, Zhuang Xiong, Pan-Pan Wu, Xue-Tao Xu

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Oxadiazole derivatives: Histone deacetylase inhibitors in anticancer therapy and drug discovery by Balaji Wamanrao Matore, Purusottam Banjare, Tanmoy Guria, Partha Pratim Roy, Jagadish Singh

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Targeting Loxosceles spider Sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism by Priscila Hess Lopes, Mário T. Murakami, Fernanda C. V. Portaro, Kerly Fernanda Mesquita Pasqualoto, Carmen van den Berg, Denise V. Tambourgi

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Medicinal applications of d-ribose l-cysteine in neuro-endocrinopathy, reproductive dysfunction and cardio-metabolic syndrome: A review of evidence in animal investigations by Oyovwi Mega Obukohwo, Falajiki Yewande Faith, Ohwin Peggy Ejiro, Mok Mishael Onyebuchi, Ayodeji Folorunsho Ajayi

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Cytotoxic effect of Cousinia verbascifolia Bunge against OVCAR-3 and HT-29 cancer cells by Sajjadi Seyed Ebrahim, Ghanadian Mustafa, Haghighi Mehrangiz, Mouhebat Leili

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Synthesis and biological activity of bisindole derivatives as novel MARK4 inhibitors by Maria Voura, Saleha Anwar, Savvas Thysiadis, Parvez Κhan, Panagiotis Dalezis, Dimitrios T. Trafalis, Md Imtaiyaz Hassan, Vasiliki Sarli

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Selective inhibition of carbonic anhydrase-IX by sulphonamide derivatives induces pH and reactive oxygen species-mediated apoptosis in cervical cancer HeLa cells by Ismail Koyuncu, Ataman Gonel, Abdurrahim Kocyigit, Ebru Temiz, Mustafa Durgun, Claudiu T. Supuran

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Development of PD3 and PD3-B for PDEδ inhibition to modulate KRAS activity by Jungeun Lee, Ho Jin Lee, Yeongcheol Lee, Bumhee Lim, Jongsik Gam, Dong-Chan Oh, Jeeyeon Lee

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Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum. by Kelly M Hennessey, Ilse C Rogiers, Han-Wei Shih, Matthew A Hulverson, Ryan Choi, Molly C McCloskey, Grant R Whitman, Lynn K Barrett, Ethan A Merritt, Alexander R Paredez, Kayode K Ojo

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Ivermectin and its synthetic derivatives - A new class of anticancer agents by Michał Sulik, Dagmara Otto-Ślusarczyk, Michał Antoszczak, Marta Struga, Adam Huczyński

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Chemical Attachment of 5-Nitrosalicylaldimine Motif to Silatrane Resulting in an Organic-Inorganic Structure with High Medicinal Significance by Mirela-Fernanda Zaltariov, Mihaela Turtoi, Dragos Peptanariu, Ana-Maria Macsim, Lilia Clima, Corneliu Cojocaru, Nicoleta Vornicu, Bianca-Iulia Ciubotaru, Alexandra Bargan, Manuela Calin, Maria Cazacu

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Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives by Maša Sinreih, Rebeka Jójárt, Zoltán Kele, Tomaž Büdefeld, Gábor Paragi, Erzsébet Mernyák, Tea Lanišnik Rižner

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Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues by Adel S. El-Azab, Alaa A.-M, Hazem A. Ghabbour, Manal A. Al-Gendy

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Synthesis, solubility and antitumor activity of maslinic acid derivatives by D. Fuentes-Rios, A. Cepero, M. García-Castro, R. Contreras-Cáceres, J.M. López-Romero, C. Luque, L. Cabeza, C. Melguizo, J. Prados

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Formulation and optimization of mesoporous silica loaded gel containing extract of Rosmarinus officinalis for treatment of acute wound healing by Raosaheb S. Shendge, Rohit Keshav Dimote

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Protective influence of hyaluronic acid on focal adhesion kinase activity in human skin fibroblasts exposed to ethanol by Donejko M, Rysiak E, Galicka E, Terlikowski R, Głażewska EK, Przylipiak A

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Target-based anticancer indole derivatives and insight into structure‒activity relationship: A mechanistic review update (2018-2021) by Ashima Dhiman, Rupam Sharma, Rajesh K. Singh

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New quinoxalinone inhibitors targeting secreted phospholipase A2 and α-glucosidase by Fatmah A. S. Alasmary, Fatima S. Alnahdi, Abir Ben Bacha, Amr M. El-Araby, Nadine Moubayed, Ahmed M. Alafeefy, Moustafa E. El-Araby

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Synthesis and evaluation of 1, 2, 3-triazole benzoate derivatives for inhibition of serine β-lactamases in extensively drug resistant pathogenic E. coli strains by Harshal S. Oman, Archana A. Kharat, Pramod S. Phatak, Kishan P. Haval, Jeetendra A. Kulkarni, Ganesh S. Kakde, Kiran R. Kharat, Dilip G. Kadam, Arun S. Kharat

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Differential effect of platelet-rich plasma fractions on β1-integrin signaling, collagen biosynthesis, and prolidase activity in human skin fibroblasts by Guszczyn T, Surażyński A, Zaręba I, Rysiak E, Popko J, Pałka J

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