Search Results - "Medicinal Chemistry"

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect by Hany E. A. Ahmed, Mohammed A. A. El-Nassag, Ahmed H. Hassan, Rawda M. Okasha, Saleh Ihmaid, Ahmed M. Fouda, Tarek H. Afifi, Ateyatallah Aljuhani, Ahmed M. El-Agrody

Connect to this object online.

Potential Impact of the Multi-Target Drug Approach in the Treatment of Some Complex Diseases by Makhoba XH, Viegas Jr C, Mosa RA, Viegas FPD, Pooe OJ

Connect to this object online.

Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives by Muhammad Rafiq, Yasir Nazir, Zaman Ashraf, Hummera Rafique, Samina Afzal, Amara Mumtaz, Mubashir Hassan, Anser Ali, Khurram Afzal, Muhammad Rizwan Yousuf, Muhammad Saleem, Katarzyna Kotwica-Mojzych, Mariusz Mojzych

Connect to this object online.

Evolution of Drug Delivery Systems for Recurrent Aphthous Stomatitis by Suharyani I, Fouad Abdelwahab Mohammed A, Muchtaridi M, Wathoni N, Abdassah M

Connect to this object online.

Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico stud... by Tarfah Al-Warhi, Mahmoud F. Abo-Ashour, Hadia Almahli, Ohoud J. Alotaibi, Mohammad M. Al-Sanea, Ghada H. Al-Ansary, Hanaa Y. Ahmed, Mahmoud M. Elaasser, Wagdy M. Eldehna, Hatem A. Abdel-Aziz

Connect to this object online.

Design, synthesis and biological Evaluation of novel chromones having 3,4-dihydropyrimidin-2(1H)-one core at C-8 in combination with triazoles: New α-glucosidase inhibitors and ant... by Kumara Swamy Taviti, T.B. Patrudu, Nagalakshmi Jeedimalla, Naresh Kumar Katari, Satyanarayana Yatam, Rambabu Gundla

Connect to this object online.

Green and chemical syntheses of silver nanoparticles: Comparative and comprehensive study on characterization, therapeutic potential, and cytotoxicity by Shivanjali Esther Arland, Jyotsna Kumar

Connect to this object online.

Phenolic phytochemistry, in vitro, in silico, in vivo, and mechanistic anti-inflammatory and antioxidant evaluations of Habenaria digitata by Hassan Hussain Almasoudi, Muhammad Saeed Jan, Mohammed H. Nahari, Abdulfattah Yahya M. Alhazmi, Abdulkarim S. Binshaya, Osama Abdulaziz, Mater H. Mahnashi, Muhammad Ibrar, Rehman Zafar, Abdul Sadiq

Connect to this object online.

Comparison of effects of anti-angiogenic agents in the zebrafish efficacy–toxicity model for translational anti-angiogenic drug discovery by Chimote G, Sreenivasan J, Pawar N, Subramanian J, Sivaramakrishnan H, Sharma S

Connect to this object online.

Identification of potential therapeutic dual inhibitors of EGFR/HER2 in breast cancer by Megha Jethwa, Aditi Gangopadhyay, Achintya Saha

Connect to this object online.

Pharmacokinetic evaluation of D-ribose after oral and intravenous administration to healthy rabbits by Alzoubi KH, Ismail ZB, AL-Essa MK, Alshogran OY, Abutayeh RF, Abu-Baker N

Connect to this object online.

Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly by Chauhan J, Yu W, Cardinale S, Opperman TJ, MacKerell AD Jr, Fletcher S, de Leeuw EPH

Connect to this object online.

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues. by Lindsay B Tulloch, Stefanie K Menzies, Andrew L Fraser, Eoin R Gould, Elizabeth F King, Marija K Zacharova, Gordon J Florence, Terry K Smith

Connect to this object online.

Novel NO-TZDs and trimethoxychalcone-based DHPMs: design, synthesis, and biological evaluation as potential VEGFR-2 inhibitors by Mater H. Mahnashi, Mohammed Nahari, Hassan Almasoudi, Abdulaziz Alhasaniah, Sara Elgazwi, Mahrous A. Abou-Salim

Connect to this object online.

A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs by Tamara Kreiss, Tyler Eck, Brittany Hart, Sreedhar Tummalapalli, David Rotella, John Siekierka

Connect to this object online.

Investigation of a Radio-Iodinated Alpha-Mangostin for Targeting Estrogen Receptor Alpha (ERα) in Breast Cancer: In Silico Design, Synthesis, and Biological Evaluation by Muchtaridi M, Nurhidayah W, Fakih TM, Kannaka K, Suzuki H, Subroto T, Uehara T

Connect to this object online.

Synthesis, In Vitro Antiproliferative Activity, and In Silico Evaluation of Novel Oxiranyl-Quinoxaline Derivatives by Vincent Montero, Marc Montana, Omar Khoumeri, Florian Correard, Marie-Anne Estève, Patrice Vanelle

Connect to this object online.

Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System by Wathoni N, Nguyen AN, Rusdin A, Umar AK, Mohammed AFA, Motoyama K, Joni IM, Muchtaridi M

Connect to this object online.

Synthesis of new 3-(4-methyl-2-arylthiazol-5-yl)-5-aryl-1,2,4-oxadiazole derivatives as potential cytotoxic and antimicrobial agents by Abdul Latif N. Shaikh, Abhijit Shinde, Abhijit Chavan, Rajendra Patil, Vivek Bobade, Pravin C. Mhaske

Connect to this object online.

Development of IKATP Ion Channel Blockers Targeting Sulfonylurea Resistant Mutant KIR6.2 Based Channels for Treating DEND Syndrome by Marien J. C. Houtman, Theres Friesacher, Xingyu Chen, Eva-Maria Z, Marcel A. G. van der Heyden, Anna Stary-Weinzinger

Connect to this object online.