Suchergebnisse - "Molecular Modelling"

New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease von Kamila Czarnecka, Małgorzata Girek, Paweł Kręcisz, Robert Skibiński, Kamil Łątka, Jakub Jończyk, Marek Bajda, Piotr Szymczyk, Grzegorz Galita, Jacek Kabziński, Ireneusz Majsterek, Alba Espargaró, Raimon Sabate, Paweł Szymański

Connect to this object online.

Identification of New Antimicrobial Peptides from Mediterranean Medical Plant <i>Charybdis pancration</i> (Steinh.) Speta von Vincenzo Cunsolo, Rosario Schicchi, Marco Chiaramonte, Luigi Inguglia, Vincenzo Arizza, Maria Grazia Cusimano, Domenico Schillaci, Antonella Di Francesco, Rosaria Saletti, Fabrizio Lo Celso, Giampaolo Barone, Maria Vitale

Connect to this object online.

Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates von Hyun Myung Lee, Rudolf Andrys, Jakub Jonczyk, Kyuneun Kim, Avinash G. Vishakantegowda, David Malinak, Adam Skarka, Monika Schmidt, Michaela Vaskova, Kamil Latka, Marek Bajda, Young-Sik Jung, Barbara Malawska, Kamil Musilek

Connect to this object online.

In Silico and In Vitro Tailoring of a Chitosan Nanoformulation of a Human Metabolic Enzyme von Paulo R. Lino, João Leandro, Mariana Amaro, Lídia M. D. Gonçalves, Paula Leandro, António J. Almeida

Connect to this object online.

Design and Synthesis of 2,6-Disubstituted-4'-Selenoadenosine-5'-<em>N</em>,<em>N</em>-Dimethyluronamide Derivatives as Human A₃ Adenosine Receptor Antagonists von Hongseok Choi, Kenneth A. Jacobson, Jinha Yu, Lak Shin Jeong

Connect to this object online.

Tethered Aryl Groups Increase the Activity of Anti-Proliferative Thieno[2,3-<i>b</i>]Pyridines by Targeting a Lipophilic Region in the Active Site of PI-PLC von Natalie A. Haverkate, Euphemia Leung, Lisa I. Pilkington, David Barker

Connect to this object online.

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biologic... von Waleed A. Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M. Abd-Alhaseeb, Sara T. Al-Rashood, Giri Babu Veerakanellore, Taghreed A. Majrashi, Eslam B. Elkaeed, Bahaa Elgendy, Paola Gratteri, Claudiu T. Supuran, Wagdy M. Eldehna, Mohamed Elagawany

Connect to this object online.

Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities von Jung-Chun Chu, Hui-Ju Tseng, Sung-Bau Lee, Kai-Cheng Hsu, Ling-Wei Hsin, Ru-Hao Liang, Tony Eight Lin, Nain-Chu Gao, Liang-Chieh Chen, Wan-Hsun Lu, Andrew H.-J Wang, Wei-Jan Huang

Connect to this object online.

Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and str... von Piotr Stępnicki, Olga Wronikowska-Denysiuk, Agata Zięba, Katarzyna M. Targowska-Duda, Agata Bartyzel, Martyna Z. Wróbel, Tomasz M. Wróbel, Klaudia Szałaj, Andrzej Chodkowski, Karolina Mirecka, Barbara Budzyńska, Emilia Fornal, Jadwiga Turło, Marián Castro, Agnieszka A. Kaczor

Connect to this object online.

Virtual design of novel Plasmodium falciparum cysteine protease falcipain-2 hybrid lactone-chalcone and isatin-chalcone inhibitors probing the S2 active site pocket von Koffi N'Guessan Placide Gabin Allangba, Mélalie Keita, Raymond Kre N'Guessan, Eugene Megnassan, Vladimir Frecer, Stanislav Miertus

Connect to this object online.

Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of Artocarpus elasticus von Janar Jenis, Aizhamal Baiseitova, Sang Hwa Yoon, Chanin Park, Jeong Yoon Kim, Zuo Peng Li, Keun Woo Lee, Ki Hun Park

Connect to this object online.

Development of <i>Staphylococcus</i> Enzybiotics: The Ph28 Gene of <i>Staphylococcus epidermidis</i> Phage PH15 Is a Two-Domain Endolysin von Magdy Mohamed Muharram, Ashraf Tawfik Abulhamd, Mohammed F. Aldawsari, Mohamed Hamed Alqarni, Nikolaos E. Labrou

Connect to this object online.

Indazole-Quinolone Hybrids as Anti-Virulence Agents against <i>Pseudomonas aeruginosa</i> von Marie Hanot, Marine Duplantier, Céline Dalle, Yani Ren, Sophie Da Nascimento, Jean-Paul Becker, Nicolas Taudon, Elodie Lohou, Pascal Sonnet

Connect to this object online.

Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B von Ahmed Elkamhawy, Sora Paik, Hyeon Jeong Kim, Jong-Hyun Park, Ashwini M. Londhe, Kyeong Lee, Ae Nim Pae, Ki Duk Park, Eun Joo Roh

Connect to this object online.

Design, Synthesis and Biological Evaluation of Neogliptin, a Novel 2-Azabicyclo[2.2.1]heptane-Based Inhibitor of Dipeptidyl Peptidase-4 (DPP-4) von Ivan O. Maslov, Tatiana V. Zinevich, Olga G. Kirichenko, Mikhail V. Trukhan, Sergey V. Shorshnev, Natalya O. Tuaeva, Maxim A. Gureev, Amelia D. Dahlén, Yuri B. Porozov, Helgi B. Schiöth, Vladimir M. Trukhan

Connect to this object online.

Dual Carbonic Anhydrase IX/XII Inhibitors and Carbon Monoxide Releasing Molecules Modulate LPS-Mediated Inflammation in Mouse Macrophages von Emanuela Berrino, Simone Carradori, Andrea Angeli, Fabrizio Carta, Claudiu T. Supuran, Paolo Guglielmi, Cecilia Coletti, Roberto Paciotti, Helmut Schweikl, Francesca Maestrelli, Elisabetta Cerbai, Marialucia Gallorini

Connect to this object online.

Design, synthesis, and bioevaluation of 1h-pyrrolo[3,2-c]pyridine derivatives as colchicine-binding site inhibitors with potent anticancer activities von Chao Wang, Yujing Zhang, Shanbo Yang, Lingyu Shi, Rong Rong, Tingting Zhang, Yudong Wu, Dongming Xing

Connect to this object online.

Presynaptic Release-Regulating Alpha2 Autoreceptors: Potential Molecular Target for Ellagic Acid Nutraceutical Properties von Isabella Romeo, Giulia Vallarino, Federica Turrini, Alessandra Roggeri, Guendalina Olivero, Raffaella Boggia, Stefano Alcaro, Giosuè Costa, Anna Pittaluga

Connect to this object online.

Metal complexes in cancer therapy &ndash; an update from drug design perspective von Ndagi U, Mhlongo N, Soliman ME

Connect to this object online.

The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes von Xiao Tang, Tarvi Teder, Bengt Samuelsson, Jesper Z. Haeggström

Connect to this object online.