Search Results - "PI3K"

Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury by Junke Song, Wen Zhang, Jinhua Wang, Haiguang Yang, Qimeng Zhou, Haigang Wang, Li Li, Guanhua Du

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Therapeutic targets and pharmacological mechanisms of Coptidis Rhizoma against ulcerative colitis: Findings of system pharmacology and bioinformatics analysis by Yuanming Yang, Yiwei Hua, Weihuan Chen, Huan Zheng, Huan Zheng, Haomeng Wu, Haomeng Wu, Haomeng Wu, Shumin Qin, Shumin Qin, Shumin Qin, Shaogang Huang, Shaogang Huang, Shaogang Huang, Shaogang Huang, Shaogang Huang

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Antidiabetic Activity of a Flavonoid-Rich Extract From Sophora davidii (Franch.) Skeels in KK-Ay Mice via Activation of AMP-Activated Protein Kinase by Yun Huang, Ji Hao, Di Tian, Yanzhang Wen, Ping Zhao, Hao Chen, Hao Chen, Yibin Lv, Xinzhou Yang

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Engineered in vivo and in vitro tumor model recapitulates vasculogenic mimicry signatures in melanoma by Qizhi Shuai, Xinrui Xu, Yuxiang Liang, Zulala Halbiyat, Xin Lu, Zixuan Hu, Zhiwei Peng, Jie An, Zhiwei Feng, Tingjuan Huang, Hong Zhao, Zhizhen Liu, Jun Xu, Jun Xie

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Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia by Daniel García-Rincón, Daniel García-Rincón, Javier Díaz-Alonso, Javier Díaz-Alonso, Juan Paraíso-Luna, Juan Paraíso-Luna, Zaira Ortega, Zaira Ortega, José Aguareles, José Aguareles, Adán de Salas-Quiroga, Adán de Salas-Quiroga, Cristina Jou, Inmaculada de Prada, Verónica Martínez-Cerdeño, Eleonora Aronica, Eleonora Aronica, Manuel Guzmán, Manuel Guzmán, María Ángeles Pérez-Jiménez, Ismael Galve-Roperh, Ismael Galve-Roperh

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From Serendipity to Rational Identification of the 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Core as a New Chemotype of AKT1 Inhibitors for Acute M... by Andrea Astolfi, Francesca Milano, Deborah Palazzotti, Jose Brea, Maria Chiara Pismataro, Mariangela Morlando, Oriana Tabarrini, Maria Isabel Loza, Serena Massari, Maria Paola Martelli, Maria Letizia Barreca

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Targeted therapies for the treatment of non-small-cell lung cancer: Monoclonal antibodies and biological inhibitors by Ana P. S. Silva, Priscila V. Coelho, Maristella Anazetti, Patricia U. Simioni

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LIPID DISTRESS-SYNDROME AND PROSPECTS OF ITS CORRECTION BY STATINES by Tatiana Denisyuk, Galina Lazareva, Vladimir Provotorov

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Advances in Neuropathic Pain Research: Selected Intracellular Factors as Potential Targets for Multidirectional Analgesics by Katarzyna Ciapała, Joanna Mika

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Protective effects of ginsenoside CK against oxidative stress-induced neuronal damage, assessed with 1H-NMR-based metabolomics by Na Li, Yanhong Zhang, Jingwei Lv, Dazhong Sun, Jianan Lin, Qihang Pang, Hui Li, Zhanhong Cao, Yaxin Liu, Zhen Li, Xingyu Fang, Dianyu Li, Haonan Bai, Yu An, Junjie Jiang, Rui Zhang, Qing Yang

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MiR-486-5p Targets CD133+ Lung Cancer Stem Cells through the p85/AKT Pathway by Massimo Moro, Orazio Fortunato, Giulia Bertolini, Mavis Mensah, Cristina Borzi, Giovanni Centonze, Francesca Andriani, Daniela Di Paolo, Patrizia Perri, Mirco Ponzoni, Ugo Pastorino, Gabriella Sozzi, Mattia Boeri

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Effect of Sophocarpine on the Pharmacokinetics of Umbralisib in Rat Plasma Using a Novel UPLC-MS/MS Method by Qinghua Weng, Xia Lan, Yingjie Wang, Chen Fan, Ren-ai Xu, Pengzhao Zhang

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NSD2 modulates Drp1-mediated mitochondrial fission in chronic renal allograft interstitial fibrosis by methylating STAT1 by Jianjian Zhang, Weibin Xie, Bin Ni, Zhuohang Li, Dengyuan Feng, Yao Zhang, Qianguang Han, Hai Zhou, Min Gu, Ruoyun Tan

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Therapeutic mechanism of Curcuma aromatica Salisb. rhizome against coronary heart disease based on integrated network pharmacology, pharmacological evaluation and lipidomics by Chenghao Fei, De Ji, Huangjin Tong, Yu Li, Lianlin Su, Yuwen Qin, Zhenhua Bian, Zhenhua Bian, Wei Zhang, Wei Zhang, Chunqin Mao, Lin Li, Tulin Lu

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Mechanisms of Rostellularia procumbens (L.) Nees on treating chronic glomerulonephritis explored by network pharmacology, RNA-seq, and in vitro experiments by Mengfan Wang, Yi Zhou, Qiuyuan Jian, Zhongzhu Ai, Shanshan Zhou

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A Novel Approach Based on Metabolomics Coupled With Intestinal Flora Analysis and Network Pharmacology to Explain the Mechanisms of Action of Bekhogainsam Decoction in the Improvem... by Xianglong Meng, Xianglong Meng, Junnan Ma, An Na Kang, Seok Yong Kang, Seok Yong Kang, Hyo Won Jung, Hyo Won Jung, Yong-Ki Park, Yong-Ki Park

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Shizao decoction for cirrhotic ascites: assessing potential targets based on network analysis combined with pharmacokinetics and metabolomics by Wenjing Li, Yujiao Hou, Yanping Wang, Ronghong Liu, Han Zhang, Yanqiong Luo, Qian Li, Mosesmanaanye Njolibimi, Bo Hong, Tao Xu

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Network Pharmacology to Explore the Molecular Mechanisms of Prunella vulgaris for Treating Hashimoto's Thyroiditis by Xiao-xiong Gan, Lin-kun Zhong, Fei Shen, Jian-hua Feng, Ya-yi Li, Si-jing Li, Wen-song Cai, Bo Xu

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A Novel Src Kinase Inhibitor, M475271, Inhibits VEGF-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration by Nermin Ali, Masanori Yoshizumi, Yoshiko Fujita, Yuki Izawa, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya, Seiji Yano, Saburo Sone, Toshiaki Tamaki

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Effect of 6-Shogaol on the Glucose Uptake and Survival of HT1080 Fibrosarcoma Cells by Angie C. Romero-Arias, Luis G. Sequeda-Castañeda, Andres F. Aristizábal-Pachón, Ludis Morales

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