Search Results - "PI3K"

Editorial: Regulation of PI3K/Akt signaling pathway: A feasible approach for natural neuroprotective agents to treat various neuron injury-related diseases by Yunhui Chen, Charles Hsu, Xiuping Chen, Heng Zhang, Wei Peng

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Xanthoceraside induces cell apoptosis through downregulation of the PI3K/Akt/Bcl-2/Bax signaling pathway in cell lines of human bladder cancer by Xue Chai, Jian-Wu Zhang, Sheng-Hui Li, Qing-Shui Cheng, Ming-Ming Qin, Chun-Yan Yang, Jia-Lin Gao, Hou-Bao Huang

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8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway by Yucong Xue, Muqing Zhang, Muqing Zhang, Miaomiao Liu, Yu Liu, Li Li, Xue Han, Xue Han, Zhenqing Sun, Li Chu, Li Chu

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Arum palaestinum delays hepatocellular carcinoma proliferation through the PI3K-AKT-mTOR signaling pathway and exhibits anticoagulant effects with antimicrobial properties by Majdi Dwikat, Johnny Amer, Nidal Jaradat, Ahmad Salhab, Ahmad Abdal Rahim, Mohammad Qadi, Aseel Aref, Mustafa Ghanim, Haya Murad, Ali Modallal, Kawkab Shalabni

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Quantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting the PDGFRβ/PI3K/AKT pathway by Qian Meng, Qian Meng, Hongwen Zhu, Yuanyuan Li, Xiaotian Peng, Tianming Wang, Hui Huang, Hu Zhou, Hu Zhou, Yuejia Liu, Yuejia Liu, Sujie Ru, Sujie Ru, Jiasheng Wu, Yueming Ma

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Screening of Bioactive Fraction of Radix Paeoniae Alba and Enhancing Anti-Allergic Asthma by Stir-Frying Through Regulating PI3K/AKT Signaling Pathway by Xia'nan Sang, Jialiang Ying, Xuedong Wan, Xin Han, Qiyuan Shan, Qiang Lyu, Qiao Yang, Kuilong Wang, Min Hao, Erlong Liu, Gang Cao

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A preclinical orthotopic model for glioblastoma recapitulates key features of human tumors and demonstrates sensitivity to a combination of MEK and PI3K pathway inhibitors by Rajaa El Meskini, Anthony J. Iacovelli, Alan Kulaga, Michelle Gumprecht, Philip L. Martin, Maureen Baran, Deborah B. Householder, Terry Van Dyke, Zoë Weaver Ohler

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Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways by Yang T, Yao S, Zhang X, Guo Y

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Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways by Ran Joo Choi, Ran Joo Choi, Siti Zuraidah Mohamad Zobir, Ben Alexander-Dann, Nitin Sharma, Marcella K.L. Ma, Brian Y.H. Lam, Giles S.H. Yeo, Weidong Zhang, Tai-Ping Fan, Andreas Bender

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Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors by Minhang Xin, Weiming Duan, Yifan Feng, Yuan-Yuan Hei, Hao Zhang, Ying Shen, Hong-Yi Zhao, Shuai Mao, San-Qi Zhang

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Induction of Apoptosis and Autophagy via sirtuin1- and PI3K/Akt/mTOR-Mediated Pathways by Plumbagin in Human Prostate Cancer Cells [Retraction] by Zhou Z, Li X, He Z, Pan S, Yang Y, Zhang X, Chow K, Yang T, Qiu J, Zhou Q, Tan J, Wang D, Zhou S

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Ethanol Extract of Brucea javanica Seed Inhibit Triple-Negative Breast Cancer by Restraining Autophagy via PI3K/Akt/mTOR Pathway by Xiaohong Chen, Xiaohong Chen, Shuang Li, Dan Li, Dan Li, Muxia Li, Muxia Li, Ziren Su, Xiaoping Lai, Changlin Zhou, Shaodan Chen, Shunxian Li, Xiaobing Yang, Jiyan Su, Yunjian Zhang

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KLF2 reduces dexamethasone-induced injury to growth plate chondrocytes by inhibiting the Runx2-mediated PI3K/AKT and ERK signalling pathways by Yulong Ma, Tao Peng, Xudong Yao, Chaonan Sun, Xiaowei Wang

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Sotetsuflavone Induces Autophagy in Non-Small Cell Lung Cancer Through Blocking PI3K/Akt/mTOR Signaling Pathway in Vivo and in Vitro by Shaohui Wang, Shaohui Wang, Shaohui Wang, Xiaoling Xu, Yanlan Hu, Yanlan Hu, Tao Lei, Tongxiang Liu, Tongxiang Liu

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Danlou Tablet Activates Autophagy of Vascular Adventitial Fibroblasts Through PI3K/Akt/mTOR to Protect Cells From Damage Caused by Atherosclerosis by Li Wang, Tong Wu, Chunying Si, He Wang, Ke Yue, Shasha Shang, Xiaohui Li, Yushan Chen, Huaimin Guan

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Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFkB pathways in cholangiocarcinoma cells by Ke FY, Wang Z, Song XL, Ma Q, Hu YP, Jiang L, Zhang YJ, Liu YB, Zhang Y, Gong W

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4-(Hydroxymethyl)catechol Extracted From Fungi in Marine Sponges Attenuates Rheumatoid Arthritis by Inhibiting PI3K/Akt/NF-κB Signaling by Jong Y. Lee, Geum J. Kim, Jin K. Choi, Jin K. Choi, Young-Ae Choi, Na-Hee Jeong, Pil-Hoon Park, Hyukjae Choi, Sang-Hyun Kim

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Plumbagin suppresses the migration and invasion of glioma cells via downregulation of MMP-2/9 expression and inaction of PI3K/Akt signaling pathway in vitro by Guanghui Chen, Yan Yue, Jun Qin, Xinping Xiao, Qing Ren, Bin Xiao

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OEA alleviates apoptosis in diabetic rats with myocardial ischemia/reperfusion injury by regulating the PI3K/Akt signaling pathway through activation of TRPV1 by Enhui Yao, Lili Luo, Chenxi Lin, Jing Wen, Yanglongfei Li, Tong Ren, Yujie Chen, Jinhua Huang, Xin Jin

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Urolithin A attenuates osteoclast differentiation and compensates for ovariectomy-induced bone loss in mice by inhibiting PI3K/AKT/mTOR signaling pathway by Wenyun Zhou, Weijun Zhou, Zibin Zhou, Yonghao Bi, Zhigao Zhou, Shaozhe Chen, Zihong Lin, Jiajie Ye, Gang Xie, Wenjie Liu, Dantao Xie, Zhen Lian, Ruiwu Zheng, Xianghua Hu, Xinjia Wang, Guixin Yuan, Guanfeng Yao

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