Suchergebnisse - "PI3K"

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors von Paweletz Cloud, Nagashima Kumiko, Andersen Jannik, Haines Brian, Chenard Melissa, Zhang Theresa, Roberts Brian, Arthur William, Chastain Michael, Frazier Jason, Klinghoffer Rich, Nebozhyn Michael, Loboda Andrey, Lynch Bethany, Feldman Igor, Dai Hongyue, Huang Pearl, Watters James

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Ginsenoside Rg3 Attenuates Lipopolysaccharide-Induced Acute Lung Injury via MerTK-Dependent Activation of the PI3K/AKT/mTOR Pathway von Jing Yang, Senyang Li, Luyao Wang, Fen Du, Xiaoliu Zhou, Qiqi Song, Junlong Zhao, Rui Fang

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Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway von Jiani Liu, Li Li, Xue Han, Yue Chen, Juanjuan Diao

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Jatrophone: a cytotoxic macrocylic diterpene targeting PI3K/AKT/NF-κB pathway, inducing apoptosis and autophagy in resistant breast cancer cells von Khawlah Shari, Rania A. El Gedaily, Rasha M. Allam, Khaled M. Meselhy, Amal E. Khaleel, Essam Abdel-Sattar

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Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells via modulating PI3K/AKT/EGFR and MAPK signaling pathways von Si Lin, Si Lin, Hui-Zhen Qin, Hui-Zhen Qin, Ze-Yu Li, Hua Zhu, Hua Zhu, Li Long, Li-Ba Xu, Li-Ba Xu

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Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway von Meihuan Zhao, Meihuan Zhao, Xueqian Tang, Xueqian Tang, Daoying Gong, Peng Xia, Peng Xia, Fushun Wang, Shijun Xu, Shijun Xu

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Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway von Wen-qiang Cao, Xiao-qian Zhai, Ji-wei Ma, Xue-qi Fu, Bai-song Zhao, Pu Zhang, Xiao-yan Fu

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First total synthesis, antitumor evaluation and target identification of mornaphthoate E: A new tubulin inhibitor template acting on PI3K/Akt signaling pathway von Peipei Shan, Tao Ye, Ying-De Tang, Hui Song, Chao Wang, Kongkai Zhu, Feifei Yang, Shi-Lei Zhang, Pei-Wen Su, Shuanhu Gao, Hua Zhang

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Effect of Spicatoside a on Anti-Osteosarcoma MG63 Cells through Reactive Oxygen Species Generation and the Inhibition of the PI3K-AKT-mTOR Pathway von Hyung-Mun Yun, Soo Hyun Kim, Yoon-Ju Kwon, Kyung-Ran Park

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Avβ3 Single-Stranded DNA Aptamer Attenuates Vascular Smooth Muscle Cell Proliferation and Migration via Ras-PI3K/MAPK Pathway von Hong-Bing Wu, Zhi-Wei Wang, Feng Shi, Zong-Li Ren, Luo-Cheng Li, Xiao-Ping Hu, Rui Hu, Bo-Wen Li

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Inhibition of Disruptor of Telomeric Silencing 1-Like Alleviated Renal Ischemia and Reperfusion Injury-Induced Fibrosis by Blocking PI3K/AKT-Mediated Oxidative Stress von Yang C, Chen Z, Yu H, Liu X

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A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway von Hui-Juan Cao, Wei Zhou, Xiao-Le Xian, Shu-Jun Sun, Pei-Jie Ding, Chun-Yu Tian, Fu-Ling Tian, Chun-Hua Jiang, Ting-Ting Fu, Shu Zhao, Jian-Ye Dai, Jian-Ye Dai, Jian-Ye Dai

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3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy von Hao Tang, Hao Tang, Kunpeng Qin, Anquan Wang, Shuang Li, Sheng Fang, Weilu Gao, Ming Lu, Wei Huang, Hui Zhang, Zongsheng Yin

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The polyphenol/saponin-rich Rhus tripartita extract has an apoptotic effect on THP-1 cells through the PI3K/AKT/mTOR signaling pathway von Hajer Tlili, Anca Macovei, Daniela Buonocore, Manuela Lanzafame, Hanen Najjaa, Anita Lombardi, Andrea Pagano, Maurizia Dossena, Manuela Verri, Abdelkarim Ben Arfa, Mohamed Neffati, Enrico Doria

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miRNA-92a-3p regulates osteoblast differentiation in patients with concomitant limb fractures and TBI via IBSP/PI3K-AKT inhibition von Liangcong Hu, Jing Liu, Hang Xue, Adriana C. Panayi, Xudong Xie, Ze Lin, Tiantian Wang, Yuan Xiong, Yiqiang Hu, Chengcheng Yan, Lang Chen, Abudula Abududilibaier, Wu Zhou, Bobin Mi, Guohui Liu

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Capsaicin Protects Against Lipopolysaccharide-Induced Acute Lung Injury Through the HMGB1/NF-κB and PI3K/AKT/mTOR Pathways von Chen H, Li N, Zhan X, Zheng T, Huang X, Chen Q, Song Z, Yang F, Nie H, Zhang Y, Zheng B, Gong Q

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Corrigendum: Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway von Zhen Qi, Renrong Wang, Rongheng Liao, Song Xue, Yongyi Wang

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N-Acetylcysteine Alleviates D-Galactose-Induced Injury of Ovarian Granulosa Cells in Female Rabbits by Regulating the PI3K/Akt/mTOR Signaling Pathway von Jiawei Cai, Yunpeng Li, Bohao Zhao, Zhiyuan Bao, Jiali Li, Shaoning Sun, Yang Chen, Xinsheng Wu

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Neuroprotective Effects of Salicin in a Gerbil Model of Transient Forebrain Ischemia by Attenuating Oxidative Stress and Activating PI3K/Akt/GSK3β Pathway von Joon-Ha Park, Tae-Kyeong Lee, Dae-Won Kim, Hyejin Sim, Jae-Chul Lee, Jong-Dai Kim, Ji-Hyeon Ahn, Choong-Hyun Lee, Young-Myeong Kim, Moo-Ho Won, Soo-Young Choi

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Fisetin, a dietary flavonoid induces apoptosis via modulating the MAPK and PI3K/Akt signalling pathways in human osteosarcoma (U-2 OS) cells von Jian-Ming Li, Wu-Yin Li, Man-Yu Huang, Xiao-Qiang Zhang

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