Search Results - "PI3K"

Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway by Xinmin Yang, Linbo Yao, Mei Yuan, Xiaoying Zhang, Monika A. Jakubowska, Pawel E. Ferdek, Lei Dai, Jingyu Yang, Tao Jin, Lihui Deng, Xianghui Fu, Dan Du, Tingting Liu, David N. Criddle, Robert Sutton, Wei Huang, Wei Huang, Qing Xia

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Sanguisorba officinalis L. suppresses non-small cell lung cancer via downregulating the PI3K/AKT/mTOR signaling pathway based on network pharmacology and experimental investigation by Hong Li, Hong Li, Jing Lin, Fei Yang, Junzhu Deng, Jia Lai, Jing Zeng, Wenjun Zou, Nan Jiang, Nan Jiang, Qianqian Huang, Qianqian Huang, Hua Li, Jian Liu, Mao Li, Zhirong Zhong, Jianming Wu, Jianming Wu, Jianming Wu

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Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways by Xudong Yao, Xingzhi Jing, Jiachao Guo, Kai Sun, Yi Deng, Yong Zhang, Fengjing Guo, Yaping Ye

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Panax notoginseng saponins promote liver regeneration through activation of the PI3K/AKT/mTOR cell proliferation pathway and upregulation of the AKT/Bad cell survival pathway in mice by Hua Zhong, Hao Wu, He Bai, Menghao Wang, Jian Wen, Jianping Gong, Mingyong Miao, Fangchao Yuan

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miRNA-98-5p Targeting IGF2BP1 Induces Mesenchymal Stem Cell Apoptosis by Modulating PI3K/Akt and p53 in Immune Thrombocytopenia by Yanan Wang, Jiamin Zhang, Yan Su, Chencong Wang, Gaochao Zhang, Xiao Liu, Qi Chen, Meng Lv, Yingjun Chang, Jun Peng, Ming Hou, Xiaojun Huang, Xiaohui Zhang

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Ginsenoside CK, rather than Rb1, possesses potential chemopreventive activities in human gastric cancer via regulating PI3K/AKT/NF-κB signal pathway by Yan Wan, Dong Liu, Jia Xia, Jin-Feng Xu, Li Zhang, Yu Yang, Jiao-Jiao Wu, Hui Ao, Hui Ao

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Chitosan/Sodium Alginate/Velvet Antler Blood Peptides Hydrogel Promoted Wound Healing by Regulating PI3K/AKT/mTOR and SIRT1/NF-κB Pathways by Mingqian Hao, Xiaojuan Peng, Shuwen Sun, Chuanbo Ding, Wencong Liu

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Ameliorative activity of standardized Coccoloba uvifera leaves extract against streptozotocin-induced diabetic rats via activation of IRS-1/PI3K/AKT/GLUT2 pathway in liver by Fatma Abdelhakim Mohamed, Rabab H. Sayed, Mohammed N. A. Khalil, Mohamed A. Salem, Amira S. El Senousy, Ali M. El-Halawany

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The Synergistic Influence of Polyflavonoids from <i>Citrus aurantifolia</i> on Diabetes Treatment and Their Modulation of the PI3K/AKT/FOXO1 Signaling Pathways: Molecular Docking Analyses and In Vivo Investigations by Mohamed A. Hassan, Ghada M. Abd Elmageed, Ibtehal G. El-Qazaz, Doaa S. El-Sayed, Lamia M. El-Samad, Heba M. Abdou

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Recombinant Human Brain Natriuretic Peptide Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting CD4+ T Cell Proliferation via PI3K/AKT/mTOR Pathway Activation by Kun-Peng Li, Hai-Yan Zhang, Xiao-Dong Xu, Ming-Yang, Tie-Jun Li, Shu-Tian Song

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Curcumin attenuates renal interstitial fibrosis of obstructive nephropathy by suppressing epithelial-mesenchymal transition through inhibition of the TLR4/NF-кB and PI3K/AKT signalling pathways by Zhaohui Wang, Zhi Chen, Bingsheng Li, Bo Zhang, Yongchao Du, Yuhang Liu, Yao He, Xiang Chen

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rhKGF-2 Attenuates Smoke Inhalation Lung Injury of Rats via Activating PI3K/Akt/Nrf2 and Repressing FoxO1-NLRP3 Inflammasome by Zhonghua Fu, Zhengying Jiang, Guanghua Guo, Xincheng Liao, Mingzhuo Liu, Zhenfang Xiong

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Pioglitazone Synthetic Analogue Ameliorates Streptozotocin-Induced Diabetes Mellitus through Modulation of ACE 2/Angiotensin 1-7 via PI3K/AKT/mTOR Signaling Pathway by Yasmin M. Ahmed, Mohamed A. Abdelgawad, Khaled Shalaby, Mohammed M. Ghoneim, Asmaa M. AboulMagd, Nada S. Abdelwahab, Hossam M. Hassan, Asmaa M. Othman

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13-Acetoxysarcocrassolide induces apoptosis in human hepatocellular carcinoma cells through mitochondrial dysfunction and suppression of the PI3K/AKT/mTOR/p70S6K signalling pathway by Chang-Min Hsu, Jen-Jie Lin, Jui-Hsin Su, Chih-I Liu

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Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways by Chuanbo Ding, Yingchun Zhao, Xueyan Chen, Yinan Zheng, Wencong Liu, Xinglong Liu

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(+)-Panduratin A induces PANC-1 human pancreatic cancer cell death preferentially under nutrient starvation by inhibiting PI3K/Akt/mTOR/autophagy signaling pathway by Sijia Sun, Min Jo Kim, Ashraf M. Omar, Nguyen Duy Phan, Suresh Awale

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Xijiao Dihuang Decoction Protects Against Murine Sepsis-Induced Cardiac Inflammation and Apoptosis via Suppressing TLR4/NF-&kappa;B and Activating PI3K/AKT Pathway by Li W, Lin M, Li J, Ding Q, Chen X, Chen H, Shen Z, Zhu X

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PLGA-Quercetin Nano-Formulation Inhibits Cancer Progression via Mitochondrial Dependent Caspase-3,7 and Independent FoxO1 Activation with Concomitant PI3K/AKT Suppression by Neera Yadav, Amit Kumar Tripathi, Amna Parveen, Shama Parveen, Monisha Banerjee

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Ethyl Acetate Extract of Selaginella doederleinii Hieron Induces Cell Autophagic Death and Apoptosis in Colorectal Cancer via PI3K-Akt-mTOR and AMPKα-Signaling Pathways by Shaoguang Li, Shaoguang Li, Shaoguang Li, Xuewen Wang, Xuewen Wang, Xuewen Wang, Gang Wang, Gang Wang, Gang Wang, Peiying Shi, Shilan Lin, Shilan Lin, Shilan Lin, Dafen Xu, Dafen Xu, Dafen Xu, Bing Chen, Bing Chen, Bing Chen, Ailin Liu, Ailin Liu, Ailin Liu, Liying Huang, Xinhua Lin, Xinhua Lin, Xinhua Lin, Hong Yao, Hong Yao, Hong Yao, Hong Yao

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Salidroside alleviates cholestasis-induced liver fibrosis by inhibiting hepatic stellate cells via activation of the PI3K/AKT/GSK-3β signaling pathway and regulating intestinal flora distribution by Xin Wang, Shuxia Cao, Yuan Huang, Liangchang Li, Dongyuan Xu, Lan Liu, Lan Liu

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