Search Results - "PI3K"

PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets by Jelena Kolic, Jocelyn E. Manning Fox, Oleg G. Chepurny, Aliya F. Spigelman, Mourad Ferdaoussi, Frank Schwede, George G. Holz, Patrick E. MacDonald

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The ameliorating effects of Guizhi Fuling Wan combined with rosiglitazone in a rat ovarian model of polycystic ovary syndrome by the PI3K/AKT/NF-κB and Nrf2/HO-1 pathways by Yongju Ye, Weimei Zhou, Yuefang Ren, Jiali Lu, Aixue Chen, Ruiying Jin, Feilan Xuan

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Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells by Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF

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Design, Synthesis, and Development of Pyrazolo[1,5-<i>a</i>]pyrimidine Derivatives as a Novel Series of Selective PI3K<i>δ</i> Inhibitors: Part II-Benzimidazole Derivatives by Mariola Stypik, Stanisław Michałek, Nina Orłowska, Marcin Zagozda, Maciej Dziachan, Martyna Banach, Paweł Turowski, Paweł Gunerka, Daria Zdżalik-Bielecka, Aleksandra Stańczak, Urszula Kędzierska, Krzysztof Mulewski, Damian Smuga, Wioleta Maruszak, Lidia Gurba-Bryśkiewicz, Arkadiusz Leniak, Wojciech Pietruś, Zbigniew Ochal, Mateusz Mach, Beata Zygmunt, Jerzy Pieczykolan, Krzysztof Dubiel, Maciej Wieczorek

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Partial Synthetic PPARƳ Derivative Ameliorates Aorta Injury in Experimental Diabetic Rats Mediated by Activation of miR-126-5p Pi3k/AKT/PDK 1/mTOR Expression by Yasmin M. Ahmed, Raha Orfali, Nada S. Abdelwahab, Hossam M. Hassan, Mostafa E. Rateb, Asmaa M. AboulMagd

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Retraction Notice to: Silencing of Long Non-coding RNA RP1-93H18.6 Acts as a Tumor Suppressor in Cervical Cancer through the Blockade of the PI3K/Akt Axis by Qian Wang, Shu-Ping Yan, Dan-Xia Chu, Ya Xie, Chun-Fang Wang, Jian-Ying Zhang, Wen-Cai Li, Rui-Xia Guo

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MiR-3188 Inhibits Non-small Cell Lung Cancer Cell Proliferation Through FOXO1-Mediated mTOR-p-PI3K/AKT-c-JUN Signaling Pathway by Chunyan Wang, Enqi Liu, Wen Li, Jue Cui, Tongxiang Li

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Rosuvastatin Enhances Alveolar Fluid Clearance in Lipopolysaccharide-Induced Acute Lung Injury by Activating the Expression of Sodium Channel and Na,K-ATPase via the PI3K/AKT/Nedd4-2 Pathway by Xu HR, Yang Q, Xiang SY, Zhang PH, Ye Y, Chen Y, Xu KW, Ren XY, Mei HX, Shen CX, Ma HY, Smith FG, Jin SW, Wang Q

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Yi-Qi-Jian-Pi-Xiao-Yu-Xie-Zhuo Formula Improves Muscle Atrophy via Modulating the IGF-1/PI3K/Akt Signaling Pathway in 5/6 Nephrectomized Rats by Hong Xia, Bingbing Zhang, Dan Yang, Chengyue Zhu, Jiudan Zhang, Hongbo Chen, Hongzhen Ma, Shouci Hu, Chao Xu, Chengqian Shi, Keda Lu, Peipei Zhang

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Salvianolic acid A attenuates CCl4-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways by Wang R, Song F, Li S, Wu B, Gu Y, Yuan Y

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GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways by Jiang Pi, Jinhuan Jiang, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai, Zheng W. Chen

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Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways by Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wang

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Exosomes derived from human umbilical cord mesenchymal stem cells alleviate acetaminophen-induced acute liver failure through activating ERK and IGF-1R/PI3K/AKT signaling pathway by Han-You Wu, Xiang-Cheng Zhang, Bing-Bing Jia, Ye Cao, Kai Yan, Jing-Yuan Li, Li Tao, Zhi-Gang Jie, Quan-Wen Liu

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Metabolomics and integrated network pharmacology analysis reveal SNKAF decoction suppresses cell proliferation and induced cell apoptisis in hepatocellular carcinoma via PI3K/Akt/P53/FoxO signaling axis by Wei Guo, Xiaohui Yao, Siyuan Lan, Chi Zhang, Hanhan Li, Zhuangzhong Chen, Ling Yu, Guanxian Liu, Yuan Lin, Shan Liu, Hanrui Chen

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Extracellular Vesicles Derived from Selenium-Deficient MAC-T Cells Aggravated Inflammation and Apoptosis by Triggering the Endoplasmic Reticulum (ER) Stress/PI3K-AKT-mTOR Pathway in Bovine Mammary Epithelial Cells by Yu Chen, Xiangqian Zhang, Jing Yang, Wen Feng, Ganzhen Deng, Shiwen Xu, Mengyao Guo

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An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule by Huxinyue Duan, Meiyan Li, Jia Liu, Jiayi Sun, Chunjie Wu, Yu Chen, Xiaohui Guo, Xinglong Liu

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Astragalus mongholicus Bunge and Curcuma aromatica Salisb. inhibits liver metastasis of colon cancer by regulating EMT via the CXCL8/CXCR2 axis and PI3K/AKT/mTOR signaling pathway by Fuyan Liu, Yan Liang, Ruolan Sun, Weicheng Yang, Zhongqing Liang, Junfei Gu, Fan Zhao, Decai Tang

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Bioassay-guided isolation of two antiproliferative metabolites from Pterocarpus indicus Willd. against TGF-β-induced prostate stromal cells (WPMY-1) proliferation via PI3K/AKT signaling pathway by San Yoon Nwe, San Yoon Nwe, San Yoon Nwe, Tamonwan Uttarawichien, Tamonwan Uttarawichien, Teerawat Boonsom, Teerawat Boonsom, Wisuwat Thongphichai, Wisuwat Thongphichai, Peththa Wadu Dasuni Wasana, Peththa Wadu Dasuni Wasana, Boonchoo Sritularak, Boonchoo Sritularak, Witchuda Payuhakrit, Suchada Sukrong, Suchada Sukrong, Pasarapa Towiwat, Pasarapa Towiwat

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Yiqi Fumai lyophilized injection ameliorates pulmonary arterial hypertension induced right heart dysfunction through ACE2-Ang (1-7)-Mas axis and PI3K/Akt/eNOS pathway by Xiao-ying Han, Yi Zhang, Xin-yu Zhang, Hai-xia Ji, Wen-zhe Wang, Ou Qiao, Xia Li, Juan Wang, De-kun Li, Ai-chun Ju, Chang-xiao Liu, Wen-yuan Gao

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18β-Glycyrrhetinic acid induces human HaCaT keratinocytes apoptosis through ROS-mediated PI3K-Akt signaling pathway and ameliorates IMQ-induced psoriasis-like skin lesions in mice by Jintao Gao, Junfan Guo, Yuejuan Nong, Wenfei Mo, Huanan Fang, Jing Mi, Qi Qi, Mengjuan Yang

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