Search Results - "PI3K"

Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents by Yujin Guo, Beibei Chen, Jinxiu Guo, Pei Jiang, Jianhua Wang, Wenxue Sun

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Cayratia albifolia C.L.Li exerts anti-rheumatoid arthritis effect by inhibiting macrophage activation and neutrophil extracellular traps (NETs) by Wei Wang, Zai-Qi Zhang, Yi-Chi Zhang, Yi-Qiang Wu, Zhuo Yang, Yong-Zhe Zheng, Jia-Hong Lu, Peng-Fei Tu, Ke-Wu Zeng

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Jowiseungki decoction affects diabetic nephropathy in mice through renal injury inhibition as evidenced by network pharmacology and gut microbiota analyses by Xianglong Meng, Junnan Ma, Seok Yong Kang, Hyo Won Jung, Yong-Ki Park

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Flavonoid compound from Agrimonia pilosa Ledeb improves adipose insulin resistance by alleviating oxidative stress and inflammation by Tingwang Guo, Yun Pan, Lin Yang, Gang Chen, Jia Deng, Liancai Zhu

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Network pharmacology-based analysis of the mechanism of Saposhnikovia divaricata for the treatment of type I allergy by Xiangsheng Li, Hui Li, Tingting Wang, Yang Zhao, Yuxin Shao, Yizhao Sun, Yanfen Zhang, Zhongcheng Liu

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Ginsenoside Rg1-Notoginsenoside R1-Protocatechuic Aldehyde Reduces Atherosclerosis and Attenuates Low-Shear Stress-Induced Vascular Endothelial Cell Dysfunction by Lei Zhang, Yuan Li, Yuan Li, Yuan Li, Xin Ma, Jiali Liu, Xiaojie Wang, Lingxiao Zhang, Chao Li, Yunlun Li, Yunlun Li, Wenqing Yang, Wenqing Yang, Wenqing Yang

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Relationships between nine neuropsychiatric disorders and cervical cancer: insights from genetics, causality and shared gene expression patterns by Jie Li, Jie Qi, Junqin Zhang, Yuan Zhang, Xianghua Huang

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Activation of PKA, p38 MAPK and ERK1/2 by gonadotropins in cumulus cells is critical for induction of EGF-like factor and TACE/ADAM17 gene expression during <it>in vitro </it>matur... by Yamashita Yasuhisa, Hishinuma Mitsugu, Shimada Masayuki

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Model‐based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2‐positive advanced or metastatic breast cancer patients by Elena M. Tosca, Elisa Borella, Chiara Piana, Salim Bouchene, Giuseppe Merlino, Alessio Fiascarelli, Paolo Mazzei, Paolo Magni

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Systems Pharmacology Approach and Experiment Evaluation Reveal Multidimensional Treatment Strategy of LiangXueJieDu Formula for Psoriasis by Jingxia Zhao, Jingxia Zhao, Yan Wang, Yan Wang, Weiwen Chen, Jing Fu, Jing Fu, Yu Liu, Yu Liu, Yu Liu, Tingting Di, Tingting Di, Cong Qi, Cong Qi, Zhaoxia Chen, Zhaoxia Chen, Ping Li, Ping Li

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The protective mechanism of Dehydromiltirone in diabetic kidney disease is revealed through network pharmacology and experimental validation by Yanzhe Wang, Yuyuan Liu, Yuyuan Liu, Sijia Chen, Fengqin Li, Yue Wu, Xinmiao Xie, Nan Zhang, Chuchu Zeng, Linnan Bai, Mengshi Dai, Ling Zhang, Xiaoxia Wang

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2-Hydroxy-3-methylanthraquinone inhibits homologous recombination repair in osteosarcoma through the MYC-CHK1-RAD51 axis by Doudou Jing, Xuanzuo Chen, Zhenhao Zhang, Fengxia Chen, Fuhua Huang, Zhicai Zhang, Wei Wu, Zengwu Shao, Feifei Pu

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Assessment of Platelet-Rich Plasma (PRP) Effects on the Proliferation and Apoptosis of Cyclophosphamide-Induced Damage in Human Granulosa Cells by Yahya Yahyavi, Abbas Karimi, Abbas Ebrahimi-Kalan, Fatemeh Ramezani, Mahdi Hasanzadeh, Soudabe Yousefi, Hourieh Sadrekarimi, Neda Abouasoltani, Mohammad Nouri, Mahdi Edalati

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Non-alcoholic fatty liver disease combined with rheumatoid arthritis exacerbates liver fibrosis by stimulating co-localization of PTRF and TLR4 in rats by Shengpeng Zhang, Peng Zhu, Jianan Yuan, Kunming Cheng, Qixiang Xu, Wei Chen, Zui Pan, Yongqiu Zheng

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Mechanistic analysis of endothelial lipase G promotion of the occurrence and development of cervical carcinoma by activating the phosphatidylinositol-4,5-bisphosphate 3-kinase/prot... by Jing Huang, Renci Liu, Yiwen Zhang, Xiujie Sheng

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New phase therapeutic pursuits for targeted drug delivery in glioblastoma multiforme by Manisha Singh, Divya Jindal, Vinayak Agarwal, Deepanshi Pathak, Mansi Sharma, Pranav Pancham, Shalini Mani, Rachana

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Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6 by Jian-Hua Liu, Chen Li, Liang Cao, Chang-Hong Zhang, Zhi-Hua Zhang

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Network pharmacology modeling identifies synergistic interaction of therapeutic and toxicological mechanisms for Tripterygium hypoglaucum Hutch by Dan Zhang, Yizhu Dong, Jintao Lv, Bing Zhang, Xiaomeng Zhang, Zhijian Lin

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Retinal Pigment Epithelial Cells Express a Functional Receptor for Glucagon-Like Peptide-1 (GLP-1) by Alessandra Puddu, Roberta Sanguineti, Fabrizio Montecucco, Giorgio L. Viviani

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Co-occurrence of opisthorchiasis and diabetes exacerbates morbidity of the hepatobiliary tract disease. by Apisit Chaidee, Sudarat Onsurathum, Kitti Intuyod, Patchareewan Pannangpetch, Chatlert Pongchaiyakul, Porntip Pinlaor, Chawalit Pairojkul, Wannaporn Ittiprasert, Christina J Cochran, Victoria H Mann, Paul J Brindley, Somchai Pinlaor

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