Search Results - "Preclinical development"

Drugs in development for toxoplasmosis: advances, challenges, and current status by Alday PH, Doggett JS

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Ex Vivo Visualization of Distribution of Intravitreal Injections in the Porcine Vitreous and Hydrogels Simulating the Vitreous by Tobias Auel, Lara Paula Scherke, Stefan Hadlich, Susan Mouchantat, Michael Grimm, Werner Weitschies, Anne Seidlitz

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Challenges and Opportunities of Nanotechnology as Delivery Platform for Tocotrienols in Cancer Therapy by Geetha Maniam, Geetha Maniam, Chun-Wai Mai, Chun-Wai Mai, Mohd Zulkefeli, Christine Dufès, Doryn Meam-Yee Tan, Doryn Meam-Yee Tan, Ju-Yen Fu

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Information Phage Therapy Research Should Report by Stephen T. Abedon

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Safety in Rats of a Novel Nasal Spray Formulation for the Prevention of Airborne Viral Infections by Mirella Tanori, Michele Pitaro, Emiliano Fratini, Eleonora Colantoni, Angela Amoresano, Simona Celentano, Barbara Chiaramonte, Mariateresa Mancuso

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Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant <i>Staphylococcus aureus</i> by Katharina Rox, Tim Becker, Andrea Schiefer, Miriam Grosse, Alexandra Ehrens, Rolf Jansen, Tilman Aden, Stefan Kehraus, Gabriele M. König, Anna K. Krome, Marc P. Hübner, Karl G. Wagner, Marc Stadler, Kenneth Pfarr, Achim Hoerauf

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A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope by Dong Li, Jing Li, Huanyu Chu, Zhuozhi Wang

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Clinical Applications of Metronomic Chemotherapy

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Isolation and Cultivation of Porcine Endothelial Cells, Pericytes and Astrocytes to Develop an In Vitro Blood-Brain Barrier Model for Drug Permeation Testing by Verena Ledwig, Stephan Reichl

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Liquid chromatography-mass spectrometry method for the quantification of an anti-sclerostin monoclonal antibody in cynomolgus monkey serum by Yuxiong Gao, Zhendong Chen, Changyong Yang, Dafang Zhong

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Pardaxin Activates Excessive Mitophagy and Mitochondria-Mediated Apoptosis in Human Ovarian Cancer by Inducing Reactive Oxygen Species by Yen-Po Chen, Po-Chang Shih, Chien-Wei Feng, Chang-Cheng Wu, Kuan-Hao Tsui, You-Hsien Lin, Hsiao-Mei Kuo, Zhi-Hong Wen

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Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals by Aruna Korde, Renata Mikolajczak, Petra Kolenc, Penelope Bouziotis, Hadis Westin, Mette Lauritzen, Michel Koole, Matthias Manfred Herth, Manuel Bardiès, Andre F. Martins, Antonio Paulo, Serge K. Lyashchenko, Sergio Todde, Sangram Nag, Efthimis Lamprou, Antero Abrunhosa, Francesco Giammarile, Clemens Decristoforo

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Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure-Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant <i>Escherichia coli</i> by Johanna Seeger, Sebastian Guenther, Katharina Schaufler, Stefan E. Heiden, Robin Michelet, Charlotte Kloft

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Using ChEMBL to Complement Schistosome Drug Discovery by Gilda Padalino, Avril Coghlan, Giampaolo Pagliuca, Josephine E. Forde-Thomas, Matthew Berriman, Karl F. Hoffmann

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Drug discovery and development: introduction to the general public and patient groups by Natesh Singh, Natesh Singh, Philippe Vayer, Shivalika Tanwar, Jean-Luc Poyet, Katya Tsaioun, Katya Tsaioun, Bruno O. Villoutreix, Bruno O. Villoutreix

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1-Oxo-3,4-dihydroisoquinoline-4-carboxamides as novel druglike inhibitors of poly(ADP-ribose) polymerase (PARP) with favourable ADME characteristics by Alexander Safrygin, Petr Zhmurov, Dmitry Dar'in, Sergey Silonov, Mariia Kasatkina, Yulia Zonis, Maxim Gureev, Mikhail Krasavin

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Recent developments of phosphodiesterase inhibitors: Clinical trials, emerging indications and novel molecules by Andrey D. Bondarev, Misty M. Attwood, Jörgen Jonsson, Vladimir N. Chubarev, Vadim V. Tarasov, Wen Liu, Helgi B. Schiöth

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Novel hybrid silicon-lipid nanoparticles deliver a siRNA to cure autosomal dominant osteopetrosis in mice. Implications for gene therapy in humans by Antonio Maurizi, Piergiorgio Patrizii, Anna Teti, Flavia Maria Sutera, Paulina Baran-Rachwalska, Chris Burns, Uttom Nandi, Michael Welsh, Nissim Torabi-Pour, Ashkan Dehsorkhi, Suzanne Saffie-Siebert

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A Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study by Lingzhi Wang, Do-Dang Khoa Phan, Nicholas Syn, Xiaoqiang Xiang, Hongyan Song, Win Lwin Thuya, Shili Yang, Andrea Li-Ann Wong, Alan Prem Kumar, Wei Peng Yong, Gautam Sethi, Paul Chi-Lui Ho, Boon Cher Goh

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Transient Transfection of the Respiratory Epithelium with Gamma Interferon for Host-Directed Therapy in Pulmonary Tuberculosis by Reena Bharti, Ashish Srivastava, Trisha Roy, Khushboo Verma, D.V. Siva Reddy, Hasham Shafi, Sonia Verma, Sunil K. Raman, Amit K. Singh, Jyotsna Singh, Lipika Ray, Amit Misra

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