Search Results - "Preclinical development"

Structure-activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4 by Ahmed Haider, Xiaoyun Deng, Olivia Mastromihalis, Stefanie K. Pfister, Troels E. Jeppesen, Zhiwei Xiao, Vi Pham, Shaofa Sun, Jian Rong, Chunyu Zhao, Jiahui Chen, Yinlong Li, Theresa R. Connors, April T. Davenport, James B. Daunais, Vahid Hosseini, Wenqing Ran, Arthur Christopoulos, Lu Wang, Celine Valant, Steven H. Liang

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Antibodies to Plasmodium vivax reticulocyte binding protein 2b are associated with protection against P. vivax malaria in populations living in low malaria transmission regions of... by Wen-Qiang He, Stephan Karl, Michael T White, Wang Nguitragool, Wuelton Monteiro, Andrea Kuehn, Jakub Gruszczyk, Camila T França, Jetsumon Sattabongkot, Marcus V G Lacerda, Wai-Hong Tham, Ivo Mueller

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Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs by Wang Y, Wallach J, Duane S, Wang Y, Wu J, Wang J, Adejare A, Ma H

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3,6'- and 1,6'-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation by Yan-Rou Tsai, Dong Seok Kim, Shih-Chang Hsueh, Kai-Yun Chen, John Chung-Che Wu, Jia-Yi Wang, Yi-Syue Tsou, Inho Hwang, Yukyung Kim, Dayeon Gil, Eui Jung Jo, Baek-Soo Han, David Tweedie, Daniela Lecca, Michael T. Scerba, Warren R. Selman, Barry J. Hoffer, Nigel H. Greig, Yung-Hsiao Chiang

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Susceptibility of HEK293 and RPTEC Cell Lines to Nephrotoxic Effects of Cefuroxime and Cefepime: A Comparative Study by V. A. Evteev, I. S. Semenova, N. D. Bunyatyan, A. B. Prokofiev

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Discovery of New 3-(Benzo[<i>b</i>]Thiophen-2-yl)Pyrrolidine-2,5-Dione Derivatives as Potent Antiseizure and Antinociceptive Agents-In Vitro and In Vivo Evaluation by Anna Rapacz, Marcin Jakubiec, Michał Abram, Jakub Jasiński, Karolina Chrzan, Małgorzata Góra, Anna Dziubina, Katarzyna Wójcik-Pszczoła, Paulina Koczurkiewicz-Adamczyk, Katarzyna Ciepiela, Elżbieta Pękala, Jolanta Obniska, Krzysztof Kamiński

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Preclinical Safety Assessment of Antineoplastic Agents Based on Live Non-Pathogenic Enteroviruses by K. V. Sivak, K. I. Stosman, E. Yu. Kalinina, M. M. Lyubishin, Ya. R. Orshanskaya, T. N. Savateeva-Lyubimova, S. B. Kazakova, D. M. Fedoseeva, A. S. Nazarov, E. I. Radion, S. M. Yudin, A. A. Keskinov, V. V. Makarov, V. S. Yudin, A. O. Zheltukhin, P. O. Vorobyev, D. V. Kochetkov, G. V. Ilyinskaya, A. V. Lipatova, P. M. Chumakov

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In silico identification of EGFR-T790M inhibitors with novel scaffolds: start with extraction of common features by Xiang M, Lei K, Fan W, Lin Y, He G, Yang M, Chen L, Mo Y

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Fexinidazole--a new oral nitroimidazole drug candidate entering clinical development for the treatment of sleeping sickness. by Els Torreele, Bernadette Bourdin Trunz, David Tweats, Marcel Kaiser, Reto Brun, Guy Mazué, Michael A Bray, Bernard Pécoul

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The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections by Mark R. Hickman, David L. Saunders, Catherine A. Bigger, Christopher D. Kane, Patrick L. Iversen

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Convection Enhanced Delivery in the Setting of High-Grade Gliomas by Chibueze D. Nwagwu, Amanda V. Immidisetti, Michael Y. Jiang, Oluwasegun Adeagbo, David C. Adamson, Anne-Marie Carbonell

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Targeted Alpha Therapy: Progress in Radionuclide Production, Radiochemistry, and Applications by Bryce J. B. Nelson, Jan D. Andersson, Frank Wuest

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Mouse models for muscular dystrophies: an overview by Maaike van Putten, Erin M. Lloyd, Jessica C. de Greef, Vered Raz, Raffaella Willmann, Miranda D. Grounds, Annemieke Aartsma-Rus, James Dowling, Maaike van Putten

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Wilms' tumor 1 -targeting cancer vaccine: Recent advancements and future perspectives by Masahiro Ogasawara

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