Zoekresultaten - "Quinoline"

Synthesis of some Novel Nitrogenous Heterocyclic Compounds with Expected Biological Activity as Antimicrobial and Cytotoxic Agents door Mohammed S. Farhan, Kawkab Y. Saour

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Berberine Promotes OATP1B1 Expression and Rosuvastatin Uptake by Inducing Nuclear Translocation of FXR and LXRα door Mingyi Liu, Dandan Zhu, Jinhua Wen, Wei Ding, Shibo Huang, Chunhua Xia, Hong Zhang, Yuqing Xiong

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Hydroxychloroquine attenuates autoimmune hepatitis by suppressing the interaction of GRK2 with PI3K in T lymphocytes door Chao Jin, Chao Jin, Bei-Bei Gao, Wen-Jing Zhou, Wen-Jing Zhou, Bao-Jing Zhao, Xing Fang, Chun-Lan Yang, Xiao-Hua Wang, Quan Xia, Ting-Ting Liu

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Synthesis of 3-[2-(1H-imidazol-2-yl)alkyl]-2-thioxo-2,3-dihydroquinazolin-4(1H)-one derivatives door O. A. Zavada, O. V. Tkachenko, I. O. Zhuravel

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Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth door Luisa Maresca, Enrica Crivaro, Francesca Migliorini, Giulia Anichini, Alessandro Giammona, Sara Pepe, Federica Poggialini, Chiara Vagaggini, Giuseppe Giannini, Serena Sestini, Lorenzo Borgognoni, Andrea Lapucci, Elena Dreassi, Maurizio Taddei, Fabrizio Manetti, Elena Petricci, Barbara Stecca

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Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington's disease mouse model door Yu Jin Hwang, Seung Jae Hyeon, Younghee Kim, Sungsu Lim, Min Young Lee, Jieun Kim, Ashwini M. Londhe, Lizaveta Gotina, Yunha Kim, Ae Nim Pae, Yong Seo Cho, Jihye Seong, Hyemyung Seo, Yun Kyung Kim, Hyunah Choo, Hoon Ryu, Sun-Joon Min

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ADMET Prediction of synthesized Heterocyclic derivatives to treat renal cancer door Rachel Cordeiro, Saba Khan, Heena Tajir, Afsha Bagwan, Mohd Anas Shaikh, Ashish Gupta

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Metabolomic Analysis of Radiation-Induced Lung Injury in Rats: The Potential Radioprotective Role of Taurine door Yiying Gao, Xugang Li, Jingjing Gao, Zhen Zhang, Yang Feng, Jihua Nie, Wei Zhu, Shuyu Zhang, Jianping Cao

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Development of PD3 and PD3-B for PDEδ inhibition to modulate KRAS activity door Jungeun Lee, Ho Jin Lee, Yeongcheol Lee, Bumhee Lim, Jongsik Gam, Dong-Chan Oh, Jeeyeon Lee

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An innovative phase I study in healthy subjects to determine the mass balance, elimination, metabolism, and absolute bioavailability of mitapivat door Chandra Prakash, Heidi Mangus, Yan Yan, Hua Yang, Varsha Iyer

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Pharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats door Zhi-Yuan Zhang, Hua Zhang, Dan Liu, Ying-Yuan Lu, Xin Wang, Pu Li, Ya-Qing Lou, Bao-Xue Yang, Ya-Xin Lou, Chuang Lu, Qiang Zhang, Guo-Liang Zhang

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2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights door Mostafa M. Elbadawi, Wagdy M. Eldehna, Amer Ali Abd El-Hafeez, Warda R. Somaa, Amgad Albohy, Sara T. Al-Rashood, Keli K. Agama, Eslam B. Elkaeed, Pradipta Ghosh, Yves Pommier, Manabu Abe

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High Selectivity of 8-Hydroxyquinoline on <i>Leishmania (Leishmania)</i> and <i>Leishmania (Viannia)</i> Species Correlates with a Potent Therapeutic Activity In Vivo door Sarah Kymberly Santos de Lima, Jéssica Adriana Jesus, Cristiano Raminelli, Márcia Dalastra Laurenti, Luiz Felipe Domingues Passero

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Synthesis, antitumour and antioxidant activities of novel α,β-unsaturated ketones and related heterocyclic analogues: EGFR inhibition and molecular modelling study door Walaa M. El-Husseiny, Magda A.-, Naglaa I. Abdel-Aziz, Adel S. El-Azab, Esam R. Ahmed, Alaa A.-M

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An aromatic imidazoline derived from chloroquinoline triggers cell cycle arrest and inhibits with high selectivity the Trypanosoma cruzi mammalian host-cells infection. door Roberto I Cuevas-Hernández, Richard M B M Girard, Luka Krstulović, Miroslav Bajić, Ariel Mariano Silber

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Drug Candidates for the Treatment of Alzheimer's Disease: New Findings from 2021 and 2022 door Sujatha L. Motebennur, Belakatte P. Nandeshwarappa, Manjunatha S. Katagi

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A Comprehensive Update of Anti-COVID-19 Activity of Heterocyclic Compounds door Nazir MS, Ahmad M, Aslam S, Rafiq A, Al-Hussain SA, Zaki MEA

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Synthesis and establishment of physico-chemical constants 2-(5-( chinoline -2-il, 2-hydroxyquinoline-4-іл)-4-R1-1,2,4-triazole-3-ілтіо) acetate acids and their esther door Т. М. Kaplaushenko, О. І. Panasenko, Y. G. Samelyuk

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Chemopreventive Potential of <i>Phyllanthus emblica</i> Fruit Extract against Colon and Liver Cancer Using a Dual-Organ Rat Carcinogenesis Model door Chonikarn Singai, Pornsiri Pitchakarn, Sirinya Taya, Warunyoo Phannasorn, Rawiwan Wongpoomchai, Ariyaphong Wongnoppavich

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Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system. door Yaneth Osorio, Bruno L Travi, Adam R Renslo, Alex G Peniche, Peter C Melby

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