Search Results - "Signal transduction"

Integrating network pharmacology, bioinformatics, and experimental validation to unveil the molecular targets and mechanisms of galangin for treating hepatocellular carcinoma by Xiaoliang Li, Mingyan Zhou, Weijia Chen, Jiangbo Sun, Yihang Zhao, Gaoan Wang, Bingshu Wang, Yipeng Pan, Junqing Zhang, Jian Xu

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Ca2+/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy by Javier Duran, Daniel Lagos, Mario Pavez, Mayarling F. Troncoso, Sebastián Ramos, Genaro Barrientos, Cristian Ibarra, Sergio Lavandero, Sergio Lavandero, Manuel Estrada

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Advances in Our Understanding of the Molecular Mechanisms of Action of Cisplatin in Cancer Therapy by Tchounwou PB, Dasari S, Noubissi FK, Ray P, Kumar S

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Growth Hormone Signaling Pathway Leading to the Induction of DNA Synthesis and Proliferation in Primary Cultured Hepatocytes of Adult Rats by Mitsutoshi Kimura, Kazuki Kurihara, Hajime Moteki, Masahiko Ogihara

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Transcriptomic and microRNA Expression Profiles Identify Biomarkers for Predicting Neo-Chemoradiotherapy Response in Esophageal Squamous Cell Carcinomas (ESCC) by Jian Wang, Pengyi Yu, Judong Luo, Zhiqiang Sun, Jingping Yu, Jianlin Wang

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Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells by Jielu Pan, Yangxian Xu, Haiyan Song, Xiqiu Zhou, Zemin Yao, Guang Ji

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Perspective on plasma membrane cholesterol efflux and spermatozoal function by Dhastagir Sultan Sheriff, Elshaari Farag Ali

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G protein coupled estrogen receptor attenuates mechanical stress-mediated apoptosis of chondrocyte in osteoarthritis via suppression of Piezo1 by Yi Sun, Ping Leng, Pengcheng Guo, Huanshen Gao, Yikai Liu, Chenkai Li, Zhenghui Li, Haining Zhang

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Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms. by Yan Hu, Bin Zhan, Brian Keegan, Ying Y Yiu, Melanie M Miller, Kathryn Jones, Raffi V Aroian

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Network pharmacology and molecular docking to elucidate the mechanism of pulsatilla decoction in the treatment of colon cancer by Huan Liu, Yuting Hu, Baoyu Qi, Chengqiu Yan, Lin Wang, Yiwen Zhang, Liang Chen

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miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma by Gabriella Misso, Mayra Rachele Zarone, Angela Lombardi, Anna Grimaldi, Alessia Maria Cossu, Carmela Ferri, Margherita Russo, Daniela Cristina Vuoso, Amalia Luce, Hiromichi Kawasaki, Maria Teresa Di Martino, Antonella Virgilio, Agostino Festa, Aldo Galeone, Giuseppe De Rosa, Carlo Irace, Massimo Donadelli, Alois Necas, Evzen Amler, Pierosandro Tagliaferri, Pierfrancesco Tassone, Michele Caraglia

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Three Members of Transmembrane-4-Superfamily, TM4SF1, TM4SF4, and TM4SF5, as Emerging Anticancer Molecular Targets against Cancer Phenotypes and Chemoresistance by Nur Syafiqah Rahim, Yuan Seng Wu, Maw Shin Sim, Appalaraju Velaga, Srinivasa Reddy Bonam, Subash C. B. Gopinath, Vetriselvan Subramaniyan, Ker Woon Choy, Sin-Yeang Teow, Ismail M. Fareez, Chandramathi Samudi, Shamala Devi Sekaran, Mahendran Sekar, Rhanye Mac Guad

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Regulation of early signaling and gene expression in the α-particle and bystander response of IMR-90 human fibroblasts by Hei Tom K, Ivanov Vladimir N, Ming Lihua, Ghandhi Shanaz A, Amundson Sally A

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Tyrosine and aurora kinase inhibitors diminish transport function of multidrug resistance-associated protein (MRP) 4 and breast cancer resistance protein (BCRP) by Rhiannon N. Hardwick, Marina Snellings, Brian C. Ferslew, Yang Lu, Kim L.R. Browuer

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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function by Maria J. Gonzalez-Rellan, Tamara Parracho, Violeta Heras, Amaia Rodriguez, Marcos F. Fondevila, Eva Novoa, Natalia Lima, Marta Varela-Rey, Ana Senra, Maria D.P. Chantada-Vazquez, Cristina Ameneiro, Ganeko Bernardo, David Fernandez-Ramos, Fernando Lopitz-Otsoa, Jon Bilbao, Diana Guallar, Miguel Fidalgo, Susana Bravo, Carlos Dieguez, Maria L. Martinez-Chantar, Oscar Millet, Jose M. Mato, Markus Schwaninger, Vincent Prevot, Javier Crespo, Gema Frühbeck, Paula Iruzubieta, Ruben Nogueiras

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Jiang Tang Xiao Ke Granule Protects Hepatic Tissue of Diabetic Mice Through Modulation of Insulin and Ras Signaling - A Bioinformatics Analysis of MicroRNAs and mRNAs Network by Ying Bai, Xueli Bao, Guangjian Jiang, Dongyu Ge, Weipeng He, Dandan Zhao, Yi Zhang, Ruijuan Dong, Jing Hua, Nan Yang, Fangfang Mo, Sihua Gao

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Mulberroside A mitigates intervertebral disc degeneration by inhibiting MAPK and modulating Ppar-γ/NF-κB pathways by Tao Xu, Hongqi Zhao, Xuan Fang, Shanxi Wang, Jian Li, Hua Wu, Weihua Hu, Rui Lu

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Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition by Lorena Avila-Carrasco, Pedro Majano, José Antonio Sánchez-Toméro, José Antonio Sánchez-Toméro, Rafael Selgas, Rafael Selgas, Manuel López-Cabrera, Manuel López-Cabrera, Abelardo Aguilera, Abelardo Aguilera, Guadalupe González Mateo, Guadalupe González Mateo, Guadalupe González Mateo

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Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway by Zhou X, Chen X, Cai JJ, Chen LZ, Gong YS, Wang LX, Gao Z, Zhang HQ, Huang WJ, Zhou H

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Kaempferia parviflora Extract Exhibits Anti-cancer Activity against HeLa Cervical Cancer Cells by Saranyapin Potikanond, Siriwoot Sookkhee, Mingkwan Na Takuathung, Pitchaya Mungkornasawakul, Pitchaya Mungkornasawakul, Nitwara Wikan, Duncan R. Smith, Wutigri Nimlamool

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