Search Results - "UGT"

Identification of the Biotransformation Pathways of a Potential Oral Male Contraceptive, 11β-Methyl-19-Nortestosterone (11β-MNT) and Its Prodrugs: An In Vitro Study Highlights the Contribution of Polymorphic Intestinal UGT2B17 by Namrata Bachhav, Dilip Kumar Singh, Diana L. Blithe, Min S. Lee, Bhagwat Prasad

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Genetic Variation in <i>CYP2D6</i>, <i>UGT1A4</i>, <i>SLC6A2</i> and <i>SLCO1B1</i> Alters the Pharmacokinetics and Safety of Mirabegron by Paula Soria-Chacartegui, Patricia Cendoya-Ramiro, Eva González-Iglesias, Samuel Martín-Vílchez, Andrea Rodríguez-Lopez, Gina Mejía-Abril, Manuel Román, Sergio Luquero-Bueno, Dolores Ochoa, Francisco Abad-Santos

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Prevalence of UDP-glucuronosyltransferase polymorphisms (UGT1A6∗2, 1A7∗12, 1A8∗3, 1A9∗3, 2B7∗2, and 2B15∗2) in a by Khalid M. Alkharfy, Basit L. Jan, Sibtain Afzal, Fahad I. Al-Jenoobi, Abdullah M. Al-Mohizea, Saleh Al-Muhsen, Rabih Halwani, Mohammad K. Parvez, Mohammed S. Al-Dosari

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Influence of SLCO1B1 521T>C, UGT2B7 802C>T and IMPDH1 &minus;106G>A Genetic Polymorphisms on Mycophenolic Acid Levels and Adverse Reactions in Chinese Autoimmune Disease Patients by Shu Q, Fan Q, Hua B, Liu H, Wang S, Liu Y, Yao Y, Xie H, Ge W

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The Genetics of Glucose-6-Phosphate-Dehydrogenase (G6PD) and Uridine Diphosphate Glucuronosyl Transferase 1A1 (UGT1A1) Promoter Gene Polymorphism in Relation to Quantitative Biochemical G6PD Activity Measurement and Neonatal Hyperbilirubinemia by Arieh Riskin, Yulia Bravdo, Clair Habib, Irit Maor, Julnar Mousa, Sizett Shahbarat, Elena Shahak, Adel Shalata

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Biocatalysis and Pharmaceuticals: A Smart Tool for Sustainable Development by Alcantara, Andres R

Subjects: “…OcUGT1…”
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Drug Metabolism, Pharmacokinetics and Bioanalysis by Lee, Hye Suk

Subjects: “…UGT…”
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Biocatalytic Process Optimization

Subjects: “…UGT-SuSy cascade reaction…”
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Age-dependent Hepatic UDP-glucuronosyltransferase Gene Expression and Activity in Children by Elizabeth Neumann, Huma Mehboob, Huma Mehboob, Jacqueline Ramírez, Snezana Mirkov, Min Zhang, Wanqing Liu

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INTRODUCTION OF AN N-GLYCOSYLATION SITE INTO UDP-GLUCURONOSYLTRANSFERASE 2B3 ALTERS ITS SENSITIVITY TO CYTOCHROME P450 3A1-DEPENDENT MODULATION by Tatsuro Nakamura, Naho Yamaguchi, Yuu Miyauchi, Tomoki Takeda, Yasushi Yamazoe, Kiyoshi Nagata, Peter I Mackenzie, Hideyuki Yamada, Yuji Ishii

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UDP-glucuronosyltransferase genetic variation in North African populations: a comparison with African and European data by Apolonia Novillo, María Gaibar, Alicia Romero-Lorca, Hassen Chaabani, Nadir Amir, Pedro Moral, M. Esther Esteban, Ana Fernández-Santander

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Tetrahydrofurofuranoid Lignans, Eudesmin, Fargesin, Epimagnolin A, Magnolin, and Yangambin Inhibit UDP-Glucuronosyltransferase 1A1 and 1A3 Activities in Human Liver Microsomes by Ria Park, Eun Jeong Park, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Im-Sook Song, Hye Suk Lee

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17β-Estradiol up-regulates UDP-glucuronosyltransferase 1A9 expression via estrogen receptor α by Sung-joon Cho, Miaoran Ning, Yanyan Zhang, Leah H. Rubin, Hyunyoung Jeong

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Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug-drug interactions for Vericiguat by Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A. Jungmann, Corina Becker, Maximilian Lobmeyer, Maria E. Trujillo, Shiyao Xu, Rolf Burghaus, Michaela Meyer

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Comparison of the inhibition potentials of icotinib and erlotinib against human UDP-glucuronosyltransferase 1A1 by Xuewei Cheng, Xia Lv, Hengyan Qu, Dandan Li, Mengmeng Hu, Wenzhi Guo, Guangbo Ge, Ruihua Dong

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Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro by Xia-Wen Liu, Yi Rong, Xing-Fei Zhang, Jun-Jun Huang, Yi Cai, Bi-Yun Huang, Liu Zhu, Bo Wu, Ning Hou, Cheng-Feng Luo

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Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice by Giulia Bortolussi, Gabriele Baj, Simone Vodret, Giulia Viviani, Tamara Bittolo, Andrés F. Muro

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Discovery and Characterization of the Key Constituents in Ginkgo biloba Leaf Extract With Potent Inhibitory Effects on Human UDP-Glucuronosyltransferase 1A1 by Hui-Lin Pang, Guang-Hao Zhu, Qi-Hang Zhou, Chun-Zhi Ai, Ya-Di Zhu, Ping Wang, Tong-Yi Dou, Yang-Liu Xia, Hong Ma, Guang-Bo Ge

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Pharmacokinetics and Pharmacogenetics of Dabigatran by A. V. Savinova, V. S. Dobrodeeva, M. M. Petrova, R. F. Nasyrova, N. A. Shnayder

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PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates by Micaela B. Reddy, Michael B. Bolger, Grace Fraczkiewicz, Laurence Del Frari, Laibin Luo, Viera Lukacova, Amitava Mitra, Joyce S. Macwan, Jim M. Mullin, Neil Parrott, Aki T. Heikkinen

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