Search Results - "allosteric"

Advances in RIPK1 kinase inhibitors by Lu Chen, Lu Chen, Xiaoqin Zhang, Yaqing Ou, Maoyu Liu, Maoyu Liu, Dongke Yu, Dongke Yu, Zhiheng Song, Lihong Niu, Lijuan Zhang, Lijuan Zhang, Jianyou Shi, Jianyou Shi

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Dietary Intake of Flavonoids and Carotenoids Is Associated with Anti-Depressive Symptoms: Epidemiological Study and In Silico-Mechanism Analysis by Seon-Joo Park, Varun Jaiswal, Hae-Jeung Lee

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Pharmacological chaperones restore proteostasis of epilepsy-associated GABAA receptor variants by Ya-Juan Wang, Hailey Seibert, Lucie Y. Ahn, Ashleigh E. Schaffer, Ting-Wei Mu

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The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB2 Receptors by Rafael Franco, Rafael Franco, Rafael Franco, Paula Morales, Gemma Navarro, Gemma Navarro, Nadine Jagerovic, Irene Reyes-Resina, Irene Reyes-Resina

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Structure-Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017-Present) by Alexandru Șandor, Ioana Ionuț, Gabriel Marc, Ilioara Oniga, Dan Eniu, Ovidiu Oniga

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Structure-activity relationships of fraxamoside as an unusual xanthine oxidase inhibitor by Rosa Maria Vitale, Lina Antenucci, Margherita Gavagnin, Gennaro Raimo, Pietro Amodeo

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From Tyrosine Kinases to Tyrosine Phosphatases: New Therapeutic Targets in Cancers and Beyond by Yu Zhou, Zhimeng Yao, Yusheng Lin, Hao Zhang

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Hemorphins Targeting G Protein-Coupled Receptors by Mohammed Akli Ayoub, Ranjit Vijayan

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Alfaxalone improved in acute stress‐induced tactile hypersensitivity and anxiety‐like behavior in mice by Kazumi Yoshizawa, Saki Ukai, Junpei Kuroda, Tsugumi Yamauchi, Daisuke Yamada, Akiyoshi Saitoh, Satoshi Iriyama, Shoichi Nishino, Satoru Miyazaki

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<i>Cannabis sativa</i> L. Bioactive Compounds and Their Protective Role in Oxidative Stress and Inflammation by Dalia M. Kopustinskiene, Ruta Masteikova, Robertas Lazauskas, Jurga Bernatoniene

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Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors in Diabetic Retinopathy: An Attractive but Elusive Choice for Drug Development by Etelka Pöstyéni, Róbert Gábriel, Andrea Kovács-Valasek

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FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions by Payal Grover, Peeyush N. Goel, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Ciriaco A. Piccirillo, Mark I. Greene

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BRAF G596R mutation in a slow-progressing melanoma by Gao L, Ma D

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Protein Persulfidation in Plants: Function and Mechanism by Peng Wang, Hua Fang, Rong Gao, Weibiao Liao

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Discovery of novel spike/ACE2 inhibitory macrocycles using in silico reinforcement learning by Lev Shapira, Shaul Lerner, Guila Assayag, Alexandra Vardi, Dikla Haham, Gideon Bar, Vicky Fidelsky Kozokaro, Maayan Elias Robicsek, Immanuel Lerner, Amit Michaeli

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Mind the Gap-Deciphering GPCR Pharmacology Using 3D Pharmacophores and Artificial Intelligence by Theresa Noonan, Katrin Denzinger, Valerij Talagayev, Yu Chen, Kristina Puls, Clemens Alexander Wolf, Sijie Liu, Trung Ngoc Nguyen, Gerhard Wolber

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Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2 by Kongfu Zhu, Chao Liu, Yuanzhu Gao, Jianping Lu, Daping Wang, Daping Wang, Huawei Zhang, Huawei Zhang

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Two Lignan Glycosides from <i>Albizia julibrissin</i> Durazz. Noncompetitively Inhibit Serotonin Transporter by Bishan Huang, Hanhe Liu, Yingyao Wu, Chan Li, Qingfa Tang, Yuan-Wei Zhang

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Therapeutic potential of targeting protein tyrosine phosphatases in liver diseases by Ao Wang, Yi Zhang, Xinting Lv, Guang Liang

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Non-carbohydrate Galectin-1 inhibitors as promising anticancer agents: Design strategies, structure activity relationship and mechanistic insights by Sridhar Goud Nerella

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