Search Results - "allosteric"

Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease by Judith A. Voynow, Shuo Zheng, Apparao B. Kummarapurugu

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Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function, 2nd Edition by Michel Kranendonk

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Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states by Varun Bahl, Catherine Lee May, Alanis Perez, Benjamin Glaser, Klaus H. Kaestner

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Metabotropic Glutamate2 Receptors Play a Key Role in Modulating Head Twitches Induced by a Serotonergic Hallucinogen in Mice by Mark J. Benvenga, Mark J. Benvenga, Stephen F. Chaney, Melvyn Baez, Thomas C. Britton, William J. Hornback, James A. Monn, Gerard J. Marek

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Preparation and in vitro evaluation of BBG-250 loaded liposomal formulation for anticancer potential by Twinkle Gupta, Priyanshu Nema, Sakshi Soni, Vivek Yadav, Sanyog Jain, Vandana Soni, Sushil K. Kashaw

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Molecular Docking Study of Phytosterols in Lygodium microphyllum Towards SIRT1 and AMPK, the in vitro Brine Shrimp Toxicity Test, and the Phenols and Sterols Levels in the Extract by Anggreini P, Kuncoro H, Sumiwi SA, Levita J

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A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects by Mikolaj Matloka, Sylwia Janowska, Piotr Pankiewicz, Sofiya Kokhanovska, Tomasz Kos, Małgorzata Hołuj, Izabela Rutkowska-Wlodarczyk, Krzysztof Abramski, Monika Janicka, Piotr Jakubowski, Maciej Świątkiewicz, Marlena Welniak-Kaminska, Joanna Hucz-Kalitowska, Paulina Dera, Lukasz Bojarski, Paweł Grieb, Piotr Popik, Maciej Wieczorek, Jerzy Pieczykolan

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P-Glycoprotein (MDR1/ABCB1) Restricts Brain Accumulation of the Novel EGFR Inhibitor EAI045 and Oral Elacridar Coadministration Enhances Its Brain Accumulation and Oral Exposure by Jing Wang, M. Merve Susam, Changpei Gan, Rolf W. Sparidans, Maria C. Lebre, Jos H. Beijnen, Alfred H. Schinkel

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Panax notoginseng saponins (PNS) attenuate Th17 cell differentiation in CIA mice via inhibition of nuclear PKM2-mediated STAT3 phosphorylation by Mei-Yu Shen, Yu-Xi Di, Xiang Wang, Feng-Xiang Tian, Ming-Fei Zhang, Fei-Ya Qian, Bao-Ping Jiang, Xue-Ping Zhou, Ling-Ling Zhou

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Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits NaV1.8 via Interactions With the DI Voltage Sensor and DII Pore Module by Kiran George, Diego Lopez-Mateos, Diego Lopez-Mateos, Tarek Mohamed Abd El-Aziz, Tarek Mohamed Abd El-Aziz, Tarek Mohamed Abd El-Aziz, Yucheng Xiao, Jake Kline, Hong Bao, Syed Raza, James D. Stockand, Theodore R. Cummins, Luca Fornelli, Matthew P. Rowe, Vladimir Yarov-Yarovoy, Vladimir Yarov-Yarovoy, Vladimir Yarov-Yarovoy, Ashlee H. Rowe, Ashlee H. Rowe

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Dimethyl Fumarate Targets MSK1, RSK1, 2 and IKKα/β Kinases and Regulates NF-κB /p65 Activation in Psoriasis: A Demonstration of the Effect on Peripheral Blood Mono... by Gesser B, Rasmussen MK, Iversen L

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Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions by Katarzyna Derszniak, Katarzyna Derszniak, Kamil Przyborowski, Karolina Matyjaszczyk, Karolina Matyjaszczyk, Martijn Moorlag, Martijn Moorlag, Bas de Laat, Bas de Laat, Maria Nowakowska, Stefan Chlopicki, Stefan Chlopicki

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LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A2A Receptor by Vinicius F. Carvalho, Tatiana P. T. Ferreira, Ana C. S. de Arantes, François Noël, François Noël, Roberta Tesch, Roberta Tesch, Carlos M. R. Sant'Anna, Eliezer J. L. Barreiro, Eliezer J. L. Barreiro, Carlos A. M. Fraga, Patrícia M. Rodrigues e Silva, Patrícia M. Rodrigues e Silva, Marco A. Martins, Marco A. Martins

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Design and Synthesis of (<i>Z</i>)-5-(Substituted benzylidene)-3-cyclohexyl-2-thioxothiazolidin-4-one Analogues as Anti-Tyrosinase and Antioxidant Compounds: In Vitro and In Silico... by Jeongin Ko, Jieun Lee, Hee Jin Jung, Sultan Ullah, Yeongmu Jeong, Sojeong Hong, Min Kyung Kang, Yu Jung Park, YeJi Hwang, Dongwan Kang, Yujin Park, Pusoon Chun, Jin-Wook Yoo, Hae Young Chung, Hyung Ryong Moon

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Valepotriates From the Roots and Rhizomes of Valeriana jatamansi Jones as Novel N-Type Calcium Channel Antagonists by Fa-Wu Dong, Fa-Wu Dong, He-Hai Jiang, He-Hai Jiang, Liu Yang, Ye Gong, Cheng-Ting Zi, Dan Yang, Chen-Jun Ye, Huan Li, Jian Yang, Jian Yang, Yin Nian, Jun Zhou, Jiang-Miao Hu

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Ginsenoside Re Treatment Attenuates Myocardial Hypoxia/Reoxygenation Injury by Inhibiting HIF-1α Ubiquitination by Huiyuan Sun, Huiyuan Sun, Huiyuan Sun, Shukuan Ling, Dingsheng Zhao, Jianwei Li, Yang Li, Hua Qu, Ruikai Du, Ying Zhang, Feng Xu, Yuheng Li, Caizhi Liu, Guohui Zhong, Shuai Liang, Zizhong Liu, Xingcheng Gao, Xiaoyan Jin, Yingxian Li, Dazhuo Shi

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The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation by Valeriya Gushchina, Nadja Kupper, Michael Schwarzkopf, Gitta Frisch, Karina Piatek, Cornelia Aigner, Alexandra Michel, Hemma Schueffl, Luca Iamartino, Luca Iamartino, Taha Elajnaf, Taha Elajnaf, Teresa Manhardt, Andrea Vlasaty, Petra Heffeter, Marcella Bassetto, Marcella Bassetto, Enikö Kállay, Martin Schepelmann

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Interacting binding insights and conformational consequences of the differential activity of cannabidiol with two endocannabinoid-activated G-protein-coupled receptors by Eliud Morales Dávila, Felipe Patricio, Mariana Rebolledo-Bustillo, David Garcia-Gomez, Juan Carlos Garcia Hernandez, Brenda L. Sanchez-Gaytan, Ilhuicamina Daniel Limón, Jose Manuel Perez-Aguilar

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The Ionotropic P2X4 Receptor has Unique Properties in the Heart by Mediating the Negative Chronotropic Effect of ATP While Increasing the Ventricular Inotropy by Bruno Bragança, Bruno Bragança, Sílvia Nogueira-Marques, Fátima Ferreirinha, Ana Patrícia Fontes-Sousa, Paulo Correia-

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Lygodium microphyllum Inhibits de Novo Lipogenesis Activity in the Hepatocytes of High-Fat High-Fructose-Induced Rats by Increasing the Levels of SIRT1 and AMPK by Anggreini P, Kuncoro H, Sumiwi SA, Levita J

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