Search Results - "allosteric"

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  1. 61
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    Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity by Yue Sun, Alberto Estevez, Tilman Schlothauer, Aaron T. Wecksler

    Published 2020
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  2. 62
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    A Model for Allosteric Communication in Drug Transport by the AcrAB-TolC Tripartite Efflux Pump by Anya Webber, Malitha Ratnaweera, Andrzej Harris, Ben F. Luisi, Véronique Yvette Ntsogo Enguéné

    Published 2022
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  3. 63
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    Novel positive allosteric modulators of A2B adenosine receptor acting as bone mineralisation promoters by Elisabetta Barresi, Chiara Giacomelli, Laura Marchetti, Emma Baglini, Silvia Salerno, Giovanni Greco, Federico Da Settimo, Claudia Martini, Maria Letizia Trincavelli, Sabrina Taliani

    Published 2021
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  4. 64
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    Metabotropic Glutamate Receptors and Neurological/Psychiatric Disorders

    Published 2019
    Subjects: “…Positive allosteric modulators…”
    DOAB: download the publication
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  5. 65
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    First‐in‐human study of deucravacitinib: A selective, potent, allosteric small‐molecule inhibitor of tyrosine kinase 2 by Ian M. Catlett, Urvi Aras, Lars Hansen, Yali Liu, Di Bei, Ihab G. Girgis, Bindu Murthy

    Published 2023
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  6. 66
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    Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593 by Asher L. Brandt, Sumanta Garai, Ayat Zagzoog, Dow P. Hurst, Lesley A. Stevenson, Roger G. Pertwee, Gregory H. Imler, Patricia H. Reggio, Ganesh A. Thakur, Robert B. Laprairie, Robert B. Laprairie

    Published 2022
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  7. 67
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    The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials by Taoyi Yang, Ting Xiao, Qi Sun, Kewei Wang

    Published 2017
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  8. 68
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    Cannabinoid receptor 1 positive allosteric modulator (GAT229) attenuates cisplatin-induced neuropathic pain in mice by Amina M. Bagher, Lenah S. Binmahfouz, Rasheed A. Shaik, Basma G. Eid

    Published 2023
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  9. 69
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    Sex-dependent anti-stress effect of an α5 subunit containing GABAA receptor positive allosteric modulator by Sean C. Piantadosi, Sean C. Piantadosi, Beverly J French, Michael M Poe, Tamara Timić, Bojan Marković, Mohan Pabba, Marianne Seney, Hyunjung Oh, Beverley Anne Orser, Miroslav M Savic, James M Cook, Etienne Sibille, Etienne Sibille, Etienne Sibille, Etienne Sibille

    Published 2016
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  10. 70
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    Allosterically activating SHP2 by oleanolic acid inhibits STAT3-Th17 axis for ameliorating colitis by Jinbo Hu, Wen Liu, Yi Zou, Chenyang Jiao, Jiazhen Zhu, Qiang Xu, Jianjun Zou, Yang Sun, Wenjie Guo

    Published 2024
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  11. 71
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    An Allosteric Modulator of the Adenosine A1 Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts by Roselyn B. Rose'Meyer, Shane M. Devine, Peter J. Scammells, Paul J. White, Anna Butcher

    Published 2013
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  12. 72
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    Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications by Elisabetta Barresi, Claudia Martini, Federico Da Settimo, Giovanni Greco, Sabrina Taliani, Chiara Giacomelli, Maria Letizia Trincavelli

    Published 2021
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  13. 73
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    P2X4 Receptor in Silico and Electrophysiological Approaches Reveal Insights of Ivermectin and Zinc Allosteric Modulation by Verónica Latapiat, Felipe E. Rodríguez, Francisca Godoy, Felipe A. Montenegro, Nelson P. Barrera, Juan P. Huidobro-Toro, Juan P. Huidobro-Toro

    Published 2017
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  14. 74
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    Effects of an oral allosteric AKT inhibitor (MK-2206) on human nasopharyngeal cancer in vitro and in vivo by Zhao YY, Tian Y, Zhang J, Xu F, Yang YP, Huang Y, Zhao HY, Zhang JW, Xue C, Lam MH, Yan L, Hu ZH, Dinglin XX, Zhang L

    Published 2014
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  15. 75
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    Identification of a Subtype-Selective Allosteric Inhibitor of GluN1/GluN3 NMDA Receptors by Yue Zeng, Yue Zeng, Yueming Zheng, Tongtong Zhang, Tongtong Zhang, Fei Ye, Li Zhan, Zengwei Kou, Shujia Zhu, Shujia Zhu, Zhaobing Gao, Zhaobing Gao, Zhaobing Gao

    Published 2022
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  16. 76
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    Diazepam is not a direct allosteric modulator of α1‐adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase‐4 by Lisa M. Williams, Xiaoji He, Tasneem M. Vaid, Alaa Abdul‐Ridha, Alice R. Whitehead, Paul R. Gooley, Ross A.D. Bathgate, Spencer J. Williams, Daniel J. Scott

    Published 2019
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  17. 77
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    Mining the Synergistic Core Allosteric Modules Variation and Sequencing Pharmacological Module Drivers in a Preclinical Model of Ischemia by Yingying Zhang, Zide Zhao, Yanan Yu, Jun Liu, Pengqian Wang, Bing Li, Xiaoxu Zhang, Yinying Chen, Zhong Wang

    Published 2018
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  18. 78
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    Mechanistic Understanding of the Palmitoylation of G<sub>o</sub> Protein in the Allosteric Regulation of Adhesion Receptor GPR97 by Hao Zhang, Guojun Chu, Gaoming Wang, Min Yao, Shaoyong Lu, Ting Chen

    Published 2022
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  19. 79
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    Untangling Dual-Targeting Therapeutic Mechanism of Epidermal Growth Factor Receptor (EGFR) Based on Reversed Allosteric Communication by Yuran Qiu, Xiaolan Yin, Xinyi Li, Yuanhao Wang, Qiang Fu, Renhua Huang, Shaoyong Lu

    Published 2021
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  20. 80
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    A3 Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect: In Vivo Studies and Molecular Mechanism of Action by Shira Cohen, Faina Barer, Sara Bar-Yehuda, Adriaan P. IJzerman, Kenneth A. Jacobson, Pnina Fishman

    Published 2014
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