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Preclinical MRI of the Kidney Methods and Protocols /
Published 2021Table of Contents: “…Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies -- Animal Models of Renal Pathophysiology and Disease -- Preparation and Monitoring of Small Animals in Renal MRI -- Reversible (Patho-)Physiologically Relevant Test Interventions: Rationale and Examples -- Preparation of Ex Vivo Rodent Phantoms for Developing, Testing, and Training MR Imaging of the Kidney and Other Organs -- Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts -- Ultrasound and Photoacoustic Imaging of the Kidney: Basic Concepts and Protocols -- Hardware Considerations for Preclinical Magnetic Resonance of the Kidney -- MRI Mapping of Renal T1: Basic Concept -- MRI Mapping of the Blood Oxygenation Sensitive Parameter T2* in the Kidney: Basic Concept -- Renal Diffusion Weighted Imaging (DWI) for Apparent Diffusion Coefficient (ADC), Intra Voxel Incoherent Motion (IVIM), and Diffusion Tensor Imaging (DTI): Basic Concept -- Dynamic Contrast Enhancement (DCE)-MRI Derived Renal Perfusion and Filtration: Basic Concepts -- Non-Invasive Renal Perfusion Measurement Using Arterial Spin Labelling (ASL) MRI: Basic Concept -- Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST)-MRI: Basic Concepts -- Sodium (23Na) MRI of the Kidney: Basic Concept -- Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concepts -- Functional Imaging Using Fluorine (19F) MR Methods: Basic Concepts -- MR Elastography of the Abdomen: Basic Concepts -- Monitoring Renal Hemodynamics and Oxygenation by Invasive Probes: Experimental Protocol -- Essential Practical Steps for MRI of the Kidney in Experimental Research -- Assessment of Renal Volume with MRI: Experimental Protocol -- Experimental Protocols for MRI Mapping of Renal T1 -- Experimental Protocols for MRI Mapping of the Blood Oxygenation Sensitive Parameters T2* and T2 in the Kidney -- Renal MRI Diffusion: Experimental Protocol -- Dynamic Contrast Enhanced (DCE)-MRI Derived Renal Perfusion and Filtration: Experimental Protocol -- Renal Blood Flow Using Arterial Spin Labeling (ASL)-MRI: Experimental Protocol and Principles -- Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST)-MRI: Experimental Protocol -- Sodium (23Na) MRI of the Kidney: Experimental Protocol -- Hyperpolarized Carbon (13C) MRI of the Kidney: Experimental Protocol -- Fluorine (19F) MRI for Assessing Inflammatory Cells in the Kidney: Experimental Protocol -- Fluorine (19F) MRI to Measure Renal Oxygen Tension and Blood Volume: Experimental Protocol -- MR Elastography of the Abdomen: Experimental Protocols -- Subsegmentation of the Kidney in Experimental MR Images Using Morphology-Based Regions-of-Interest or Multiple-Layer Concentric Objects -- De-Noising for Improved Parametric MRIof the Kidney: Protocol for Non-Local Means Filtering -- Analysis Protocols for MRI Mapping of Renal T1 -- Analysis Protocols for MRI Mapping of the Blood Oxygenation Sensitive Parameters T2* and T2 in the Kidney -- Analysis of Renal Diffusion Weighted Imaging (DWI) Using Apparent Diffusion Coefficient (ADC) and Intra Voxel Incoherent Motion (IVIM) Models -- Analysis Protocol for Dynamic Contrast Enhanced (DCE)-MRI of Renal Perfusion and Filtration -- Quantitative Analysis of Renal Perfusion by Arterial Spin Labeling -- Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST)-MRI -- Analysis Protocol for Renal Sodium (23Na) MR Imaging -- Analysis Methods for Hyperpolarized Carbon (13C) MRI of the Kidney -- Data Preparation Protocol for Low Signal-to-Noise Ratio Fluorine-19 MRI.…”
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