Search Results - "animal models"

Preclinical characterization of dostarlimab, a therapeutic anti-PD-1 antibody with potent activity to enhance immune function in in vitro cellular assays and in vivo animal models by Sujatha Kumar, Srimoyee Ghosh, Geeta Sharma, Zebin Wang, Marilyn R. Kehry, Margaret H. Marino, Tamlyn Y. Neben, Sharon Lu, Shouqi Luo, Simon Roberts, Sridhar Ramaswamy, Hadi Danaee, David Jenkins

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Translational Insights into Mechanisms and Therapy of Organ Dysfunction in Sepsis and Trauma

Subjects: “…animal models…”
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Reconstruction of Bone Defect Combined with Massive Loss of Periosteum Using Injectable Human Mesenchymal Stem Cells in Biocompatible Ceramic Scaffolds in a Porcine Animal Model by Chun-Cheng Lin, Shih-Chieh Lin, Chao-Ching Chiang, Ming-Chau Chang, Oscar Kuang-Sheng Lee

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Changes in Membrane Protein Clustering in Peripheral Lymphocytes in an Animal Model of Depression Parallel Those Observed in Naïve Depression Patients: Implications for the Development of Novel Biomarkers of Depression by Raquel Romay-Tallon, Erin Kulhawy, Kyle J. Brymer, Josh Allen, Tania Rivera-Baltanas, Jose M. Olivares, Lisa E. Kalynchuk, Hector J. Caruncho

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Synergistic Effect of Ginsenoside Rh2 Combines with Ionizing Radiation on CT26/<i>luc</i> Colon Carcinoma Cells and Tumor-Bearing Animal Model by Shan-Chih Lee, Chao-Yu Shen, Wei-Hsun Wang, Yen-Po Lee, Keng-Wei Liang, Ying-Hsiang Chou, Yeu-Sheng Tyan, Jeng-Jong Hwang

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<i>Punica granatum</i> L. Extract Shows Cardioprotective Effects Measured by Oxidative Stress Markers and Biomarkers of Heart Failure in an Animal Model of Metabolic Syndrome by Joanna Niewiadomska, Monika Kasztura, Izabela Janus, Elżbieta Chełmecka, Dominika Marta Stygar, Piotr Frydrychowski, Aneta Wojdyło, Agnieszka Noszczyk-Nowak

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Treatment With Medicinal Mushroom Extract Mixture Inhibits Translation and Reprograms Metabolism in Advanced Colorectal Cancer Animal Model as Evidenced by Tandem Mass Tags Proteomics Analysis by Boris Jakopovic, Anita Horvatić, Marko Klobučar, Andrea Gelemanović, Petra Grbčić, Nada Oršolić, Ivan Jakopovich, Sandra Kraljević Pavelić

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Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes <i>Mellitus</i> by Sónia Rocha, Andreia Amaro, Marcos D. Ferreira-Junior, Carina Proença, Artur M. S. Silva, Vera M. Costa, Sara Oliveira, Diogo A. Fonseca, Sónia Silva, Maria Luísa Corvo, Marisa Freitas, Paulo Matafome, Eduarda Fernandes

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Impact of Subacute Exposure to T-2 Toxin and Zearalenone on the Pharmacokinetics of Midazolam as CYP3A Probe Drug in a Porcine Animal Model: A Pilot Study by Wim Schelstraete, Mathias Devreese, Siska Croubels

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Intravitreal Administration Effect of Adipose-Derived Mesenchymal Stromal Cells Combined with Anti-VEGF Nanocarriers, in a Pharmaceutically Induced Animal Model of Retinal Vein Occlusion by Eleni Gounari, Anastasia Komnenou, Evangelia Kofidou, Stavroula Nanaki, Dimitrios Bikiaris, Stavroula Almpanidou, Kokkona Kouzi, Vasileios Karampatakis, George Koliakos

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Novel nano-carriers with N-formylmethionyl-leucyl-phenylalanine-modified liposomes improve effects of C16-angiopoietin 1 in acute animal model of multiple sclerosis by Xiao-Xiao Fu, Han Qu, Jing Wang, Hua-Ying Cai, Hong Jiang, Hao-Hao Chen, Shu Han

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Dietary Compound Isoliquiritigenin, an Antioxidant from Licorice, Suppresses Triple-Negative Breast Tumor Growth via Apoptotic Death Program Activation in Cell and Xenograft Animal Models by Po-Han Lin, Yi-Fen Chiang, Tzong-Ming Shieh, Hsin-Yuan Chen, Chun-Kuang Shih, Tong-Hong Wang, Kai-Lee Wang, Tsui-Chin Huang, Yong-Han Hong, Sing-Chung Li, Shih-Min Hsia

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Cerebral Small Vessel Diseases: From Vessel Alterations to Cortical Parenchymal Injury

Subjects: “…Animal Models…”
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Mechanizmy regulacji odpowiedzi immunologicznej w zwierzęcym modelu alergicznego kontaktowego zapalenia skóry [Mechanisms involved in the regulation of immune response in animal model of allergic contact dermatitis] by Anna Strzępa, Tomasz Stramek, Marian Szczepanik

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Increased levels of synaptic proteins involved in synaptic plasticity after chronic intraocular pressure elevation and modulation by brain-derived neurotrophic factor in a glaucoma animal model by Hae-Young Lopilly Park, Si Won Kim, Jie Hyun Kim, Chan Kee Park

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Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer's Disease Animal Model by HyeJu Jeong, Ok Joon Kim, Seung-Hun Oh, Sanghoon Lee, Han A. Reum Lee, Kee Ook Lee, Boo-Yong Lee, Nam Keun Kim

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Temporary Botulinum Immobilization of Residuum Muscles for Facilitation of the Initial Ingrowth of Skin to the Porous Skin and Bone Integrated Pylon in the Technology of Direct Skeletal Attachment: Large Animal Model by Zachary Bohart, Charles Cassidy, David Merrill, Mario Villani, Rosanna Villani, Leo Cappabianca, Mark Pitkin, Mark Pitkin

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Fasudil, a Rho-Kinase Inhibitor, Exerts Cardioprotective Function in Animal Models of Myocardial Ischemia/Reperfusion Injury: A Meta-Analysis and Review of Preclinical Evidence and Possible Mechanisms by Yue-yue Huang, Jian-ming Wu, Tong Su, Song-yue Zhang, Xiao-ji Lin

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RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models by Uwe Grether, Richard H. Foxton, Sabine Gruener, Claudia Korn, Atsushi Kimbara, Anja Osterwald, Elisabeth Zirwes, Sabine Uhles, Janina Thoele, Nadine Colé, Mark Rogers-Evans, Stephan Röver, Matthias Nettekoven, Rainer E. Martin, Jean-Michel Adam, Jürgen Fingerle, Caterina Bissantz, Wolfgang Guba, André Alker, Anna M. Szczesniak, Ross F. Porter, Tom J. Toguri, Franco Revelant, Agnès Poirier, Camille Perret, Lotte Winther, Antonello Caruso, Filomena Fezza, Mauro Maccarrone, Mauro Maccarrone, Melanie E. M. Kelly, Sascha Fauser, Christoph Ullmer

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Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation by Hai Zhang, Qing-Cuo Ren, Yan Ren, Lin Zhao, Fan Yang, Yi Zhang, Wen-Ji Zhao, Yu-Zhu Tan, Xiao-Fei Shen

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