Search Results - "antisense"

What Can RNA-Based Therapy Do for Monogenic Diseases? by Luka A. Clarke, Margarida D. Amaral

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AON-mediated Exon Skipping Restores Ciliation in Fibroblasts Harboring the Common Leber Congenital Amaurosis CEP290 Mutation by Xavier Gerard, Isabelle Perrault, Sylvain Hanein, Eduardo Silva, Karine Bigot, Sabine Defoort-Delhemmes, Marlèene Rio, Arnold Munnich, Daniel Scherman, Josseline Kaplan, Antoine Kichler, Jean-Michel Rozet

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Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery by Santiago Grijalvo, Gustavo Puras, Jon Zárate, Myriam Sainz-Ramos, Nuseibah A. L. Qtaish, Tania López, Mohamed Mashal, Noha Attia, David Díaz, Ramon Pons, Eduardo Fernández, José Luis Pedraz, Ramon Eritja

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An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells by Amanda Ackley, Alexandra Lenox, Kenneth Stapleton, Stuart Knowling, Tim Lu, Kenny S Sabir, Peter K Vogt, Kevin V Morris

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As Technologies for Nucleotide Therapeutics Mature, Products Emerge by Jennifer M. Beierlein, Laura M. McNamee, Fred D. Ledley

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Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material by Hiroki Tanaka, Nae Takata, Yu Sakurai, Tokuyuki Yoshida, Takao Inoue, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Masatoshi Maeki, Manabu Tokeshi, Hidetaka Akita

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A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans by Nicholas R Jones, Melissa A Pegues, Mark A McCrory, Walter Singleton, Claudette Bethune, Brenda F Baker, Daniel A Norris, Rosanne M Crooke, Mark J Graham, Alexander J Szalai

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De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics by Roya Pedram Fatemi, Dmitry Velmeshev, Mohammad Ali Faghihi

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Recent Advancements in Development and Therapeutic Applications of Genome-Targeting Triplex-Forming Oligonucleotides and Peptide Nucleic Acids by Yu Mikame, Asako Yamayoshi

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Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription by Kazuo Suzuki, Chantelle Ahlenstiel, Katherine Marks, Anthony D Kelleher

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Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2'-MOE-ASOs by Colby S. Shemesh, Rosie Z. Yu, Mark S. Warren, Michael Liu, Mirza Jahic, Brandon Nichols, Noah Post, Song Lin, Daniel A. Norris, Eunju Hurh, Jane Huang, Tanya Watanabe, Scott P. Henry, Yanfeng Wang

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Lessons Learned from Discontinued Clinical Developments in Duchenne Muscular Dystrophy by Theodora Markati, Liesbeth De Waele, Liesbeth De Waele, Urlike Schara-Schmidt, Laurent Servais, Laurent Servais

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A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides by Andreas Dieckmann, Peter H. Hagedorn, Yvonne Burki, Christine Brügmann, Marco Berrera, Martin Ebeling, Thomas Singer, Franz Schuler

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Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells by Stuart Knowling, Kenneth Stapleton, Anne-Marie W Turner, Eugen Uhlmann, Thomas Lehmann, Jörg Vollmer, Kevin V Morris

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Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA by Paola Valentini, Bianca Pierattini, Elsa Zacco, Damiano Mangoni, Stefano Espinoza, Natalie A. Webster, Byron Andrews, Piero Carninci, Gian Gaetano Tartaglia, Luca Pandolfini, Stefano Gustincich

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Promising strategies employing nucleic acids as antimicrobial drugs by Luís Moreira, Nuno M. Guimarães, Rita S. Santos, Joana A. Loureiro, Maria C. Pereira, Nuno F. Azevedo

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Immune Checkpoint Inhibitors for Vaccine Improvements: Current Status and New Approaches by Alexander Batista-Duharte, Fakhri Hassouneh, Pablo Alvarez-Heredia, Alejandra Pera, Rafael Solana

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Aptamer-iRNAs as Therapeutics for Cancer Treatment by Mario M. Soldevilla, Daniel Meraviglia-Crivelli de Caso, Ashwathi P. Menon, Fernando Pastor

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Induced-Decay of Glycine Decarboxylase Transcripts as an Anticancer Therapeutic Strategy for Non-Small-Cell Lung Carcinoma by Jing Lin, Jia Hui Jane Lee, Kathirvel Paramasivam, Elina Pathak, Zhenxun Wang, Zacharias Aloysius Dwi Pramono, Bing Lim, Keng Boon Wee, Uttam Surana

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Systemic DNA/RNA heteroduplex oligonucleotide administration for regulating the gene expression of dorsal root ganglion and sciatic nerve by Hidetoshi Kaburagi, Tetsuya Nagata, Mitsuhiro Enomoto, Takashi Hirai, Masaki Ohyagi, Kensuke Ihara, Kie Yoshida-Tanaka, Satoe Ebihara, Ken Asada, Hiroyuki Yokoyama, Atsushi Okawa, Takanori Yokota

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