Search Results - "base editing"

Base editing rescues acid α-glucosidase function in infantile-onset Pompe disease patient-derived cells by Chloe L. Christensen, Shih-Hsin Kan, Perla Andrade-Heckman, Allisandra K. Rha, Jerry F. Harb, Raymond Y. Wang

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Base editing corrects the common Salla disease SLC17A5 c.115C>T variant by Jerry F. Harb, Chloe L. Christensen, Shih-Hsin Kan, Allisandra K. Rha, Perla Andrade-Heckman, Laura Pollard, Richard Steet, Jeffrey Y. Huang, Raymond Y. Wang

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Efficient Generation of Pathogenic A-to-G Mutations in Human Tripronuclear Embryos via ABE-Mediated Base Editing by Guanglei Li, Xinyi Liu, Shisheng Huang, Yanting Zeng, Guang Yang, Zongyang Lu, Yu Zhang, Xu Ma, Lisheng Wang, Xingxu Huang, Jianqiao Liu

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CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations by Siyu Chen, Wanhua Xie, Zhiquan Liu, Huanhuan Shan, Mao Chen, Yuning Song, Hao Yu, Liangxue Lai, Zhanjun Li

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Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model by Gaetano Naso, Soragia Athina Gkazi, Christos Georgiadis, Vignesh Jayarajan, Joanna Jacków, Roland Fleck, Leanne Allison, Olumide Kayode Ogunbiyi, John Alexander McGrath, Dusko Ilic, Wei-Li Di, Anastasia Petrova, Waseem Qasim

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Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells by Anya T. Joynt, Erin W. Kavanagh, Gregory A. Newby, Shakela Mitchell, Alice C. Eastman, Kathleen C. Paul, Alyssa D. Bowling, Derek L. Osorio, Christian A. Merlo, Shivani U. Patel, Karen S. Raraigh, David R. Liu, Neeraj Sharma, Garry R. Cutting

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CRISPR-based editing strategies to rectify EYA1 complex genomic rearrangement linked to haploinsufficiency by Hwalin Yi, Yejin Yun, Won Hoon Choi, Hye-Yeon Hwang, Ju Hyuen Cha, Heeyoung Seok, Jae-Jin Song, Jun Ho Lee, Sang-Yeon Lee, Daesik Kim

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Precise Genome Editing Techniques and Applications

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A novel base editor SpRY-ABE8eF148A mediates efficient A-to-G base editing with a reduced off-target effect by Guo Li, Yaxian Cheng, Yeqiu Li, Hongru Ma, Zhongji Pu, Sa Li, Yiqiang Zhao, Xingxu Huang, Yuan Yao

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Information Infrastructures within European Health Care Working with the Installed Base /

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Editing of homologous globin genes by nickase-deficient base editor mitigates large intergenic deletions in HSPCs by Anila George, Poornasree Sadanandan, Nithin Sam Ravi, B. Vaishnavi, Srujan Marepally, Saravanbhavan Thangavel, Shaji R. Velayudhan, Alok Srivastava, Kumarasamypet M Mohankumar

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Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors by Michael Gapinske, Jackson Winter, Devyani Swami, Lauren Gapinske, Wendy S. Woods, Shraddha Shirguppe, Angelo Miskalis, Anna Busza, Dana Joulani, Collin J. Kao, Kurt Kostan, Anne Bigot, Rashid Bashir, Pablo Perez-Pinera

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Improving Editing Efficiency for the Sequences with NGH PAM Using xCas9-Derived Base Editors by Xinyi Liu, Guanglei Li, Xueliang Zhou, Yunbo Qiao, Ruixuan Wang, Shaohui Tang, Jianqiao Liu, Lisheng Wang, Xingxu Huang

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Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity by Kai Cheng, Cao Li, Jiachuan Jin, Xuezhen Qian, Jiayin Guo, Limini Shen, YiChen Dai, Xue Zhang, Zhanwei Li, Yichun Guan, Fei Zhou, Jin Tang, Jun Zhang, Bin Shen, Xin Lou

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Reduced off-target effect of NG-BE4max by using NG-HiFi system by Huanhuan Shan, Zhiquan Liu, Yingqi Jia, Siyu Chen, Mao Chen, Yuning Song, Tingting Sui, Liangxue Lai, Zhanjun Li

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Single-swap editing for the correction of common Duchenne muscular dystrophy mutations by Andreas C. Chai, Francesco Chemello, Hui Li, Takahiko Nishiyama, Kenian Chen, Yu Zhang, Efraín Sánchez-Ortiz, Adeeb Alomar, Lin Xu, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson

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DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome by Jiayin Guo, Xiaoxu Chen, Zhiwei Liu, Haifeng Sun, Yu Zhou, Yichen Dai, Yu'e Ma, Lei He, Xuezhen Qian, Jianying Wang, Jie Zhang, Yichen Zhu, Jun Zhang, Bin Shen, Fei Zhou

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Messenger RNA brings gene editing a step closer to treat muscular dystrophies by John Jacob

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Gene editing innovations and their applications in cardiomyopathy research by Eirini Kyriakopoulou, Thomas Monnikhof, Eva van Rooij

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MultiEditR: The first tool for the detection and quantification of RNA editing from Sanger sequencing demonstrates comparable fidelity to RNA-seq by Mitchell G. Kluesner, Rafail Nikolaos Tasakis, Taga Lerner, Annette Arnold, Sandra Wüst, Marco Binder, Beau R. Webber, Branden S. Moriarity, Riccardo Pecori

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