Search Results - "biologist"

Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds by Wei-Chia Tseng, Hannah E. Loeb, Wuhong Pei, Chon-Hw, Lisha Xu, Celine V. Cluzeau, Christopher A. Wassif, Benjamin Feldman, Shawn M. Burgess, William J. Pavan, Forbes D. Porter

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Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice by Insa Bultmann-Mellin, Jeroen Essers, Paula M. van Heijingen, Harald von Melchner, Gerhard Sengle, Anja Sterner-Kock

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A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations by Michael Buchert, Franziska Rohde, Moritz Eissmann, Niall Tebbutt, Ben Williams, Chin Wee Tan, Alexander Owen, Yumiko Hirokawa, Alexandra Gnann, Gertraud Orend, Gayle Orner, Rod H. Dashwood, Joan K. Heath, Matthias Ernst, Klaus-Peter Janssen

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Zika virus non-structural protein NS4A restricts eye growth in Drosophila through regulation of JAK/STAT signaling by Sneh Harsh, Yulong Fu, Eric Kenney, Zhe Han, Ioannis Eleftherianos

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Seipin knockout in mice impairs stem cell proliferation and progenitor cell differentiation in the adult hippocampal dentate gyrus via reduced levels of PPARγ by Guoxi Li, Libin Zhou, Ying Zhu, Conghui Wang, Sha Sha, Xunde Xian, Yong Ji, George Liu, Ling Chen

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Depletion of regulatory T cells leads to an exacerbation of delayed-type hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade by Sara Marie Atkinson, Ute Hoffmann, Alf Hamann, Emil Bach, Niels Banhos Danneskiold-Samsøe, Karsten Kristiansen, Kyle Serikawa, Brian Fox, Kim Kruse, Claus Haase, Søren Skov, Anneline Nansen

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Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development by Kristin M. Ates, Tong Wang, Trevor Moreland, Rajalakshmi Veeranan-Karmegam, Manxiu Ma, Chelsi Jeter, Priya Anand, Wolfgang Wenzel, Hyung-Goo Kim, Lynne A. Wolfe, Joshi Stephen, David R. Adams, Thomas Markello, Cynthia J. Tifft, Robert Settlage, William A. Gahl, Graydon B. Gonsalvez, May Christine Malicdan, Heather Flanagan-Steet, Y. Albert Pan

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Enhancer of Polycomb and the Tip60 complex repress hematological tumor initiation by negatively regulating JAK/STAT pathway activity by Alessandro A. Bailetti, Lenny J. Negrón-Piñeiro, Vishal Dhruva, Sneh Harsh, Sean Lu, Aisha Bosula, Erika A. Bach

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Yeast-model-based study identified myosin- and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis by Piotr Soczewka, Damian Kolakowski, Iwona Smaczynska-de Rooij, Weronika Rzepnikowska, Kathryn R. Ayscough, Joanna Kaminska, Teresa Zoladek

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Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney by Garrett Brinkley, Hyeyoung Nam, Eunhee Shim, Richard Kirkman, Anirban Kundu, Suman Karki, Yasaman Heidarian, Jason M. Tennessen, Juan Liu, Jason W. Locasale, Tao Guo, Shi Wei, Jennifer Gordetsky, Teresa L. Johnson-Pais, Devin Absher, Dinesh Rakheja, Anil K. Challa, Sunil Sudarshan

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Repurposing the aldose reductase inhibitor and diabetic neuropathy drug epalrestat for the congenital disorder of glycosylation PMM2-CDG by Sangeetha Iyer, Feba S. Sam, Nina DiPrimio, Graeme Preston, Jan Verheijen, Kausalya Murthy, Zachary Parton, Hillary Tsang, Jessica Lao, Eva Morava, Ethan O. Perlstein

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Impaired neural differentiation and glymphatic CSF flow in the Ccdc39 rat model of neonatal hydrocephalus: genetic interaction with L1cam by A. Scott Emmert, Eri Iwasawa, Crystal Shula, Preston Schultz, Diana Lindquist, R. Scott Dunn, Elizabeth M. Fugate, Yueh-Chiang Hu, Francesco T. Mangano, June Goto

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Phenotypic overlap in the contribution of individual genes to CNV pathogenicity revealed by cross-species computational analysis of single-gene mutations in humans, mice and zebraf... by Sandra C. Doelken, Sebastian Köhler, Christopher J. Mungall, Georgios V. Gkoutos, Barbara J. Ruef, Cynthia Smith, Damian Smedley, Sebastian Bauer, Eva Klopocki, Paul N. Schofield, Monte Westerfield, Peter N. Robinson, Suzanna E. Lewis

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Pumilio2-deficient mice show a predisposition for epilepsy by Philipp Follwaczny, Rico Schieweck, Therese Riedemann, Antonia Demleitner, Tobias Straub, Anna H. Klemm, Martin Bilban, Bernd Sutor, Bastian Popper, Michael A. Kiebler

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Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity by Sarah J. Annesley, Sui T. Lay, Shawn W. De Piazza, Oana Sanislav, Eleanor Hammersley, Claire Y. Allan, Lisa M. Francione, Minh Q. Bui, Zhi-Ping Chen, Kevin R. W. Ngoei, Flora Tassone, Bruce E. Kemp, Elsdon Storey, Andrew Evans, Danuta Z. Loesch, Paul R. Fisher

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Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers by Adam D. Pfefferle, Yash N. Agrawal, Daniel C. Koboldt, Krishna L. Kanchi, Jason I. Herschkowitz, Elaine R. Mardis, Jeffrey M. Rosen, Charles M. Perou

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Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers by Jill Sergesketter Napierala, Yanjie Li, Yue Lu, Kevin Lin, Lauren A. Hauser, David R. Lynch, Marek Napierala

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X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities by Jakub Sikora, Jennifer Leddy, Maria Gulinello, Steven U. Walkley

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Recessive, gain-of-function toxicity in an APOL1 BAC transgenic mouse model mirrors human APOL1 kidney disease by Gizelle M. McCarthy, Angelo Blasio, Olivia G. Donovan, Lena B. Schaller, Althea Bock-Hughes, Jose M. Magraner, Jung Hee Suh, Calum F. Tattersfield, Isaac E. Stillman, Shrijal S. Shah, Zsuzsanna K. Zsengeller, Balajikarthick Subramanian, David J. Friedman, Martin R. Pollak

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Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model by Qi Xu, Sanna Junttila, Andreas Scherer, Khem Raj Giri, Oona Kivelä, Ilya Skovorodkin, Juha Röning, Susan E. Quaggin, Hans-Peter Marti, Jingdong Shan, Anatoly Samoylenko, Seppo J. Vainio

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