Search Results - "blood–brain barrier"

Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening by Khalid A. Agha, Nader E. Abo-Dya, Abdul Rashid Issahaku, Clement Agoni, Mahmoud E. S. Soliman, Eatedal H. Abdel-Aal, Zakaria K. Abdel-Samii, Tarek S. Ibrahim

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Pharmacological mTOR inhibitors in ameliorating Alzheimer's disease: current review and perspectives by Pei-Lun Xie, Meng-Yu Zheng, Ran Han, Wei-Xin Chen, Jin-Hua Mao

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Clinical pharmacokinetics of leriglitazone and a translational approach using PBPK modeling to guide the selection of the starting dose in children by Estefania Traver, Laura Rodríguez‐Pascau, Uwe Meya, Guillem Pina, Silvia Pascual, Sonia Poli, David Eckland, Jeroen van deWetering, Alice Ke, Andreas Lindauer, Marc Martinell, Pilar Pizcueta

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Comparative pharmacokinetics of tetramethylpyrazine phosphate in rat plasma and extracellular fluid of brain after intranasal, intragastric and intravenous administration by Dongmei Meng, Haoyang Lu, Shanshan Huang, Minyan Wei, Pingtian Ding, Xianglin Xiao, Yuehong Xu, Chuanbin Wu

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Pharmacokinetics, Tissue Distribution and Excretion of Paeonol and Its Major Metabolites in Rats Provide a Further Insight Into Paeonol Effectiveness by Xintong Hu, Xintong Hu, Liqin Ding, Shijie Cao, Lina Cheng, Lina Cheng, Kun Wang, Kun Wang, Chenxi Guang, Chenxi Guang, Wei Li, Wei Li, Kazuo Koike, Feng Qiu, Feng Qiu

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Drug Delivery Systems in the Development of Novel Strategies for Glioblastoma Treatment by Wiam El Kheir, Bernard Marcos, Nick Virgilio, Benoit Paquette, Nathalie Faucheux, Marc-Antoine Lauzon

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Loss of miR-101-3p Promotes Transmigration of Metastatic Breast Cancer Cells through the Brain Endothelium by Inducing COX-2/MMP1 Signaling by Rania Harati, Mohammad G. Mohammad, Abdelaziz Tlili, Raafat A. El-Awady, Rifat Hamoudi

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Targeting Insulin-Like Growth Factor-1 Signaling into the Central Nervous System for Promoting Myelin Repair by Nadine Wilczak, Jacques De Keyser, Daniel Chesik

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Liposomal-Based Formulations: A Path from Basic Research to Temozolomide Delivery Inside Glioblastoma Tissue by Roxana-Maria Amarandi, Alina Ibanescu, Eugen Carasevici, Luminita Marin, Brindusa Dragoi

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The involvement of perivascular spaces or tissues in the facial intradermal brain-targeted delivery by Wei Yang, Bing-Hui Jin, Ya-Jing Chen, Chang Cao, Jia-Zhen Zhu, Ying-Zheng Zhao, Xi-Chong Yu, Fan-Zhu Li

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Lentivector Integration Sites in Ependymal Cells From a Model of Metachromatic Leukodystrophy: Non-B DNA as a New Factor Influencing Integration by Robert G McAllister, Jiahui Liu, Matthew W Woods, Sean K Tom, C Anthony Rupar, Stephen D Barr

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A Brain-Targeted Approach to Ameliorate Memory Disorders in a Sporadic Alzheimer's Disease Mouse Model via Intranasal Luteolin-Loaded Nanobilosomes by Manal A. Elsheikh, Yasmin A. El-Feky, Majid Mohammad Al-Sawahli, Merhan E. Ali, Ahmed M. Fayez, Haidy Abbas

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Maternal immunoglobulins are distributed in the offspring's brain to support the maintenance of cortical interneurons in the postnatal period by Keiko Morimoto, Rikuo Takahashi, Goro Takahashi, Michio Miyajima, Kazunori Nakajima

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Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota by Zheng-Wei Zhang, Chun-Sheng Gao, Heng Zhang, Jian Yang, Ya-Ping Wang, Li-Bin Pan, Hang Yu, Chi-Yu He, Hai-Bin Luo, Zhen-Xiong Zhao, Xin-Bo Zhou, Yu-Li Wang, Jie Fu, Pei Han, Yu-Hui Dong, Gang Wang, Song Li, Yan Wang, Jian-Dong Jiang, Wu Zhong

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Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy by Zhenkun Zong, Lei Hua, Zhen Wang, Haoyue Xu, Chengkun Ye, Bomin Pan, Zongren Zhao, Longzhen Zhang, Jun Lu, Hongmei Liu, Rutong Yu

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Therapeutic Ultrasound as a Treatment Modality for Physiological and Pathological Ageing Including Alzheimer's Disease by Jürgen Götz, Gina Richter-Stretton, Esteban Cruz

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In Vivo Antidepressant Effect of <i>Passiflora edulis</i> f. <i>flavicarpa</i> into Cationic Nanoparticles: Improving Bioactivity and Safety by Jovelina Samara Ferreira Alves, Alaine Maria dos Santos Silva, Rodrigo Moreira da Silva, Pamella Rebeca Fernandes Tiago, Thais Gomes de Carvalho, Raimundo Fernandes de Araújo Júnior, Eduardo Pereira de Azevedo, Norberto Peporine Lopes, Leandro De Santis Ferreira, Elaine Cristina Gavioli, Arnóbio Antônio da Silva-Júnior, Silvana Maria Zucolotto

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All-stage targeted therapy for the brain metastasis from triple-negative breast cancer by Zimiao Luo, Sunyi Wu, Jianfen Zhou, Weixia Xu, Qianzhu Xu, Linwei Lu, Cao Xie, Yu Liu, Weiyue Lu

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Brain targeting stealth lipomers of combined antiepileptic-anti-inflammatory drugs as alternative therapy for conventional anti-Parkinson's by Iman M. Higazy

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Systematic review of melatonin in cerebral ischemia-reperfusion injury: critical role and therapeutic opportunities by Chenguang Zhang, Yumei Ma, Yating Zhao, Na Guo, Chen Han, Qian Wu, Changqing Mu, Yue Zhang, Shutong Tan, Jian Zhang, Jian Zhang, Xu Liu

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