Search Results - "blood–brain barrier"

The Landscape of Novel Therapeutics and Challenges in Glioblastoma Multiforme: Contemporary State and Future Directions by Karam Khaddour, Tanner M. Johanns, George Ansstas

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The Proteasome Inhibitor Marizomib Evokes Endoplasmic Reticulum Stress and Promotes Apoptosis in Human Glioblastoma Cells by Magdalena Kusaczuk, Natalia Tyszka, Rafał Krętowski, Marzanna Cechowska-Pasko

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High Incidence of Intracerebral Hemorrhaging Associated with the Application of Low-Intensity Focused Ultrasound Following Acute Cerebrovascular Injury by Intracortical Injection by Evgenii Kim, Jared Van Reet, Hyun-Chul Kim, Kavin Kowsari, Seung-Schik Yoo

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Antioxidant Polyphenols of <i>Antirhea borbonica</i> Medicinal Plant and Caffeic Acid Reduce Cerebrovascular, Inflammatory and Metabolic Disorders Aggravated by High-Fat Diet-Induc... by Janice Taïlé, Matthieu Bringart, Cynthia Planesse, Jessica Patché, Philippe Rondeau, Bryan Veeren, Patricia Clerc, Anne Gauvin-Bialecki, Steeve Bourane, Olivier Meilhac, David Couret, Marie-Paule Gonthier

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Cytotoxic and Antiproliferative Activity of LASSBio-2208 and the Attempts to Determine Its Drug Metabolism and Pharmacokinetics In Vitro Profile by Raysa Magali Pillpe-Meza, Wesley Leandro Gouveia, Gisele Barbosa, Carlos A. M. Fraga, Eliezer J. Barreiro, Lidia Moreira Lima

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Antibody-Based In Vivo Imaging of Central Nervous System Targets-Evaluation of a Pretargeting Approach Utilizing a TCO-Conjugated Brain Shuttle Antibody and Radiolabeled Tetrazines by Christoph Bredack, Martin R. Edelmann, Edilio Borroni, Luca C. Gobbi, Michael Honer

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Plasma lipidome profiling of newborns with antenatal exposure to Zika virus. by Nieli Rodrigues da Costa Faria, Adriano Britto Chaves-Filho, Luiz Carlos Junior Alcantara, Isadora Cristina de Siqueira, Juan Ignacio Calcagno, Sayuri Miyamoto, Ana Maria Bispo de Filippis, Marcos Yukio Yoshinaga

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Development of a nanoprecipitation method for the entrapment of a very water soluble drug into Eudragit RL nanoparticles by Sara Salatin, Jaleh Barar, Mohammad Barzegar-Jalali, Khosro Adibkia, Farhad Kiafar, Mitra Jelvehgari

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Biological evaluation and in silico studies of novel compounds as potent TAAR1 agonists that could be used in schizophrenia treatment by Yunjie Wang, Zhaofeng Liu, Jing Lu, Wenyan Wang, Lin Wang, Yifei Yang, Hongbo Wang, Liang Ye, Jianzhao Zhang, Jingwei Tian

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Preclinical Studies of Canagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, and Donepezil Combined Therapy in Alzheimer's Disease by Gabriela Dumitrita Stanciu, Daniela Carmen Ababei, Carmen Solcan, Veronica Bild, Andrei Ciobica, Sorin-Ioan Beschea Chiriac, Loredana Maria Ciobanu, Bogdan-Ionel Tamba

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Novel Multitarget Hydroxamic Acids with a Natural Origin CAP Group against Alzheimer's Disease: Synthesis, Docking and Biological Evaluation by Margarita Neganova, Yulia Aleksandrova, Evgenii Suslov, Evgenii Mozhaitsev, Aldar Munkuev, Dmitry Tsypyshev, Maria Chicheva, Artem Rogachev, Olga Sukocheva, Konstantin Volcho, Sergey Klochkov

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P-glycoprotein Mediated Efflux Limits Substrate and Drug Uptake in a Preclinical Brain Metastases of Breast Cancer Model by Chris E Adkins, Rajendar Kumar Mittapalli, Vamshi Krishna Manda, Mohamed Ismail Nounou, Afroz Shareef Mohammad, Tori Breanne Terrrell, Kaci Ann Bohn, Celik eYasemin, Tiffany Renee Grothe, Julie Ann Lockman, Paul Richard Lockman

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Docosahexaenoic acid-mediated, targeted and sustained brain delivery of curcumin microemulsion by Rajshree L. Shinde, Padma V. Devarajan

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Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning by Anisha K. Nigam, Jeremiah D. Momper, Anupam Anand Ojha, Sanjay K. Nigam

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Polymer Pro-Drug Nanoparticles for Sustained Release of Cytotoxic Drugs Evaluated in Patient-Derived Glioblastoma Cell Lines and In Situ Gelling Formulations by Catherine E. Vasey, Robert J. Cavanagh, Vincenzo Taresco, Cara Moloney, Stuart Smith, Ruman Rahman, Cameron Alexander

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Target-Based Virtual Screening of Natural Compounds Identifies a Potent Antimalarial With Selective Falcipain-2 Inhibitory Activity by Amad Uddin, Amad Uddin, Sonal Gupta, Taj Mohammad, Diksha Shahi, Afzal Hussain, Mohamed F. Alajmi, Hesham R. El-Seedi, Imtaiyaz Hassan, Shailja Singh, Mohammad Abid

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Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors by Jong Hee Choi, Jong Hee Choi, Minhee Jang, Seikwan Oh, Seung-Yeol Nah, Ik-Hyun Cho, Ik-Hyun Cho, Ik-Hyun Cho

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Gallic Acid Prevents the Oxidative and Endoplasmic Reticulum Stresses in the Hippocampus of Adult-Onset Hypothyroid Rats by Vanessa Blas-Valdivia, Margarita Franco-Colín, Placido Rojas-Franco, Alberto Chao-Vazquez, Alberto Chao-Vazquez, Edgar Cano-Europa

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Icaritin Provides Neuroprotection in Parkinson's Disease by Attenuating Neuroinflammation, Oxidative Stress, and Energy Deficiency by Hao Wu, Xi Liu, Ze-Yu Gao, Ming Lin, Xin Zhao, Yi Sun, Xiao-Ping Pu

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LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein by Verena Peek, Lois M. Harden, Jelena Damm, Ferial Aslani, Stephan Leisengang, Joachim Roth, Rüdiger Gerstberger, Marita Meurer, Maren von Köckritz-Blickwede, Sabine Schulz, Bernhard Spengler, Christoph Rummel

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