Resultados da pesquisa - "catalytic"

Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells Por Sidneia Sousa Santos, Larissa de Oliveira Cavalcanti Peres Rodrigues, Vanessa Martins, Maria Petrosino, Karim Zuhra, Kelly Ascenção, Abhishek Anand, Reham Mahmoud Abdel-Kader, Mohamed Z. Gad, Carole Bourquin, Csaba Szabo

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Receptor tyrosine kinases as a therapeutic target by natural compounds in cancer treatment Por Toheeb A. Balogun, Oluwasegun M. Ige, Abdullahi O. Alausa, Chijioke O. Onyeani, Zainab A. Tiamiyu, Damilola A. Omoboyowa, Oluwatosin A. Saibu, Olayemi T. Abdullateef

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Comparative study of trastuzumab modification analysis using mono/multi-epitope affinity technology with LC-QTOF-MS Por Chengyi Zuo, Jingwei Zhou, Sumin Bian, Qing Zhang, Yutian Lei, Yuan Shen, Zhiwei Chen, Peijun Ye, Leying Shi, Mao Mu, Jia-Huan Qu, Zhengjin Jiang, Qiqin Wang

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Design, Characterization, and Antimicrobial Evaluation of Copper Nanoparticles Utilizing Tamarixinin a Ellagitannin from Galls of <i>Tamarix aphylla</i> Por Mohamed A. A. Orabi, Mounir M. Salem-Bekhit, Ehab I. Taha, El-Shaymaa, Omaish Salman Alqahtani, Fakhria A. Al-Joufi, Basel A. Abdel-Wahab, Ali Mohamed Alshabi, Hamad S. Alyami, Javed Ahmad, Tsutomu Hatano

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Targeting of cholera toxin A (ctxA) gene by zinc finger nuclease: pitfalls of using gene editing tools in prokaryotes Por Nafiseh Hosseini, Hossein Khanahmad, Bahram Nasr Esfahani, Mojgan Bandehpour, Laleh Shariati, Nushin Zahedi, Bahram Kazemi

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Changing the face of hepatitis C management &ndash; the design and development of sofosbuvir Por Noell BC, Besur SV, deLemos AS

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Successes and challenges of the One Health approach in Kenya over the last decade Por Peninah M. Munyua, M. Kariuki Njenga, Eric M. Osoro, Clayton O. Onyango, Austine O. Bitek, Athman Mwatondo, Mathew K. Muturi, Norah Musee, Godfrey Bigogo, Elkanah Otiang, Fredrick Ade, Sara A. Lowther, Robert F. Breiman, John Neatherlin, Joel Montgomery, Marc-Alain Widdowson

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Restraint Stress Alters Expression of Glucocorticoid Bioavailability Mediators, Suppresses Nrf2, and Promotes Oxidative Stress in Liver Tissue Por Hsiao-Jou Cortina Chen, Tsz Yip, Johnny K. Lee, Juliani Juliani, Conrad Sernia, Andrew F. Hill, Nickolas A. Lavidis, Jereme G. Spiers

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Protocetraric and Salazinic Acids as Potential Inhibitors of SARS-CoV-2 3CL Protease: Biochemical, Cytotoxic, and Computational Characterization of Depsidones as Slow-Binding Inact... Por Lorenza Fagnani, Lisaurora Nazzicone, Pierangelo Bellio, Nicola Franceschini, Donatella Tondi, Andrea Verri, Sabrina Petricca, Roberto Iorio, Gianfranco Amicosante, Mariagrazia Perilli, Giuseppe Celenza

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The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes Por You-Cheng Hseu, Xuan-Zao Chen, Yugandhar Vudhya Gowrisankar, Hung-Rong Yen, Jing-Yuan Chuang, Hsin-Ling Yang

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Pyridoxamine Supplementation Effectively Reverses the Abnormal Phenotypes of Zebrafish Larvae With PNPO Deficiency Por Po-Yuan Chen, Hung-Chi Tu, Verne Schirch, Martin K. Safo, Tzu-Fun Fu, Tzu-Fun Fu

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Ficus benghalensis as Potential Inhibitor of 5α-Reductase for Hair Growth Promotion: In Vitro, In Silico, and In Vivo Evaluation Por Jawaria Iltaf, Sobia Noreen, Muhammad Fayyaz ur Rehman, Shazia Akram Ghumman, Fozia Batool, Muhammad Mehdi, Sara Hasan, Bushra Ijaz, Muhammad Safwan Akram, Haider Butt

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Linear and Machine Learning modelling for spatiotemporal disease predictions: Force-of-Infection of Chagas disease. Por Julia Ledien, Zulma M Cucunubá, Gabriel Parra-Henao, Eliana Rodríguez-Monguí, Andrew P Dobson, Susana B Adamo, María-Gloria Basáñez, Pierre Nouvellet

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Unveiling the Role of Ecto-5'-Nucleotidase/CD73 in Astrocyte Migration by Using Pharmacological Tools Por Marija Adzic, Marija Adzic, Nadezda Nedeljkovic

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Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer Por Petros D. Grivas, Kathleen C. Day, Andreas Karatsinides, Alyssa Paul, Nazia Shakir, Iya Owainati, Monica Liebert, Lakshmi P. Kunju, Dafydd Thomas, Maha Hussain, Mark L. Day

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Design, in silico and pharmacological evaluation of a peptide inhibitor of BACE-1 Por Renata Boldin, Renata Boldin, Bianca Cestari Zychar, Luis Roberto C. Gonçalves, Juliana Mozer Sciani

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Design, synthesis and biological evaluation of novel O-substituted tryptanthrin oxime derivatives as c-Jun N-terminal kinase inhibitors Por Igor A. Schepetkin, Anastasia R. Kovrizhina, Ksenia S. Stankevich, Andrei I. Khlebnikov, Liliya N. Kirpotina, Mark T. Quinn, Matthew J. Cook

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LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia Por Gao Sun, Gabriela da Silva Xavier, Tracy Gorman, Claire Priest, Antonia Solomou, David J. Hodson, Marc Foretz, Benoit Viollet, Pedro-Luis Herrera, Helen Parker, Frank Reimann, Fiona M. Gribble, Stephanie Migrenne, Christophe Magnan, Anna Marley, Guy A. Rutter

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Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1 Por Edavana VK, Yu X, Dhakal IB, Williams S, Ning B, Cook IT, Caldwell D, Falany CN, Kadlubar S

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Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors Por Cheng-Zhi Gao, Wei Dong, Zhi-Wen Cui, Qiong Yuan, Xia-Min Hu, Qing-Ming Wu, Xianlin Han, Yao Xu, Zhen-Li Min

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