Search Results - "cytochrome P450"

Unraveling pleiotropic effects of rifampicin by using physiologically based pharmacokinetic modeling: Assessing the induction magnitude of P‐glycoprotein-cytochrome P450 3A4 dual substrates by Xian Pan, Shinji Yamazaki, Sibylle Neuhoff, Mian Zhang, Venkatesh Pilla Reddy

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Inhibitory Effects of Eight Green Tea Catechins on Cytochrome P450 1A2, 2C9, 2D6, and 3A4 Activities by Takashi Satoh, Haruka Fujisawa, Ami Nakamura, Natsuko Takahashi, Kazuhiro Watanabe

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CsCYT75B1, a Citrus CYTOCHROME P450 Gene, Is Involved in Accumulation of Antioxidant Flavonoids and Induces Drought Tolerance in Transgenic <i>Arabidopsis</i> by Muhammad Junaid Rao, Yuantao Xu, Xiaomei Tang, Yue Huang, Jihong Liu, Xiuxin Deng, Qiang Xu

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Identifying cytochrome P450s involved in oxidative metabolism of synthetic cannabinoid N‐(adamantan‐1‐yl)‐1‐(5‐fluoropentyl)‐1H‐indole‐3‐carboxamide (STS‐135) by Sabrina Jones, Azure L. Yarbrough, William E. Fantegrossi, Paul L. Prather, John M. Bush, Anna Radominska‐Pandya, Ryoichi Fujiwara

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A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions by Sebastian Frechen, Juri Solodenko, Thomas Wendl, André Dallmann, Ibrahim Ince, Thorsten Lehr, Jörg Lippert, Rolf Burghaus

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Effect of Cytochrome P450 (CYP) 2D6 Genetic Polymorphism on the Inhibitory Action of Antidepressants on CYP2D6-Mediated Dopamine Formation from p-Tyramine by Toshiro Niwa, Mayumi Yanai, Maya Matsumoto, Marina Shizuku

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Simultaneous Determination of Five Cytochrome P450 Probe Substrates and Their Metabolites and Organic Anion Transporting Polypeptide Probe Substrate in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry by Jae-Kyung Heo, Hyun-Ji Kim, Ga-Hyun Lee, Boram Ohk, Sangkyu Lee, Kyung-Sik Song, Im Sook Song, Kwang-Hyeon Liu, Young-Ran Yoon

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Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies by Qiu JX, Zhou ZW, He ZX, Zhang X, Zhou SF, Zhu S

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Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P450 (CYP)1B1 by Dietary Antioxidants, Omega-3 Fatty Acids, in Mice by Guodong Zhou, Weiwu Jiang, Guobin Xia, Lihua Wang, Molly Richardson, Chun Chu, Bhagavatula Moorthy

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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1 by Shizhen Ding, Shizhen Ding, Guotao Lu, Biying Wang, Jie Xiang, Chunxia Hu, Zhijie Lin, Zhijie Lin, Yanbing Ding, Yanbing Ding, Weiming Xiao, Weiming Xiao, Weiming Xiao, Weijuan Gong, Weijuan Gong, Weijuan Gong, Weijuan Gong

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POLYMORPHISM OF CYTOCHROME P450 2A6 (CYP2A6*1 AND CYP2A6*4) AMONG JAVANESE INDONESIAN SMOKER AND NON SMOKER by Christine Patramurti, Sugiyanto, Arief Nurrochmad, Sudibyo Martono

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Evaluation of the cytochrome P450 2C19 and 3A4 inhibition potential of the complement factor 5a receptor 1 antagonist ACT‐1014‐6470 in vitro and in vivo by Marion Anliker‐Ort, Jasper Dingemanse, Stephane Delahaye, Luboš Janů, John van denAnker, Benjamin Berger, Priska Kaufmann

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Validation of a 3-h Sampling Interval to Assess Variability in Cytochrome P450 3A Phenotype and the Impact of Induction and Mechanism-Based Inhibition Using Midazolam as a Probe Substrate by Madelé van Dyk, Asha J. Kapetas, Ashley M. Hopkins, A. David Rodrigues, Manoli Vourvahis, Michael J. Sorich, Andrew Rowland

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Effect of nivasorexant (ACT‐539313), a selective orexin‐1‐receptor antagonist, on multiple cytochrome P450 probe substrates in vitro and in vivo using a cocktail approach in healthy subjects by Benjamin Berger, Priska Kaufmann, Matthias Berse, Alexander Treiber, Nathalie Grignaschi, Jasper Dingemanse

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Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the&nbsp;activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study by Su JH, Chang C, Xiang Q, Zhou ZW, Luo R, Yang L, He ZX, Yang HT, Li J, Bei Y, Xu JM, Zhang MJ, Zhang QH, Su ZJ, Huang YD, Pang JY, Zhou SF

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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

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Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function by Michel Kranendonk

Subjects: “…Cytochrome P450…”
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Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function, 2nd Edition by Michel Kranendonk

Subjects: “…Cytochrome P450…”
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Genome-wide microRNA profiles identify miR-107 as a top miRNA associating with expression of the CYP3As and other drug metabolizing cytochrome P450 enzymes in the liver by Marwa Tantawy, Joseph M. Collins, Danxin Wang

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Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention against colorectal tumors in single Japanese cohort using daily low-dose aspirin: insights into future personalized treatments by Hiroshi Yamazaki, Makiko Shimizu, Takahiro Otani, Ami Mizugaki, Kanae Mure, Sadao Suzuki, Hideki Ishikawa

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