Search Results - "cytochrome P450"

Combined Treatment with Herbal Medicine and Drug Ameliorates Inflammation and Metabolic Abnormalities in the Liver of an Amyotrophic Lateral Sclerosis Mouse Model by Hee Ra Park, Eun Jin Yang

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Characteristics of intracellular Ca2+ signals consisting of two successive peaks in hepatocytes during liver regeneration after 70% partial hepatectomy in rats by Taira Z, Ueda Y, Monmasu H, Yamase D, Miyake S, Shiraishi M

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Antiproliferative and Anti-Inflammatory Activities of Deprungsith Formulation and Its Bioactive Compounds Against Mild Psoriasis and Potential of Metabolic Herb-Drug Interactions by Kesara Na-Bangchang PhD, Monthaka Teerachaisakul PhD, Phunuch Muhamad PhD, Yositha Kasemnitichok BSc, Nattida Sangnarong BSc, Kanyarat Boonprasert PhD, Mayuri Tarasuk PhD, Tullayakorn Plengsuriyakarn PhD

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Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker by Miao Zhang, Miao Zhang, Miao Zhang, Zhiheng Yu, Zhiheng Yu, Zhiheng Yu, Xueting Yao, Xueting Yao, Zihan Lei, Zihan Lei, Zihan Lei, Kaijing Zhao, Wenqian Wang, Xue Zhang, Xijing Chen, Dongyang Liu, Dongyang Liu

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Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs by Léa Darnaud, Clément Delage, Youssef Daali, Anne-Priscille Trouvin, Serge Perrot, Nihel Khoudour, Nadia Merise, Laurence Labat, Bruno Etain, Frank Bellivier, Célia Lloret-Linares, Vanessa Bloch, Emmanuel Curis, Xavier Declèves

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St. John's wort extract with a high hyperforin content does not induce P‐glycoprotein activity at the human blood-brain barrier by Myriam El Biali, Michael Wölfl‐Duchek, Matthias Jackwerth, Severin Mairinger, Maria Weber, Karsten Bamminger, Stefan Poschner, Ivo Rausch, Natalie Schindler, Irene Hernández Lozano, Walter Jäger, Lukas Nics, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Martin Bauer, Oliver Langer

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Schisandra chinensis essential oil attenuates acetaminophen-induced liver injury through alleviating oxidative stress and activating autophagy by Jing Zhao, Kaixin Ding, Manting Hou, Yuanhua Li, Xiaorong Hou, Wenzhang Dai, Zhiyong Li, Jun Zhao, Wenlong Liu, Zhaofang Bai

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Temephos resistance in Aedes aegypti in Colombia compromises dengue vector control. by Nelson Grisales, Rodolphe Poupardin, Santiago Gomez, Idalyd Fonseca-Gonzalez, Hilary Ranson, Audrey Lenhart

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Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency by Mónica Fernández-Cancio, Núria Camats, Christa E. Flück, Adam Zalewski, Bernhard Dick, Brigitte M. Frey, Raquel Monné, Núria Torán, Laura Audí, Amit V. Pandey

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A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS‐CoV‐2(−)/(+) populations by Claire Steinbronn, Yashpal S. Chhonker, Jenell Stewart, Hannah Leingang, Kate B. Heller, Meighan L. Krows, Michael Paasche‐Orlow, Anna Bershteyn, Helen C. Stankiewicz Karita, Vaidehi Agrawal, Miriam Laufer, Raphael Landovitz, Mark Wener, Daryl J. Murry, Christine Johnston, Ruanne V. Barnabas, Samuel L. M. Arnold

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Clinical assessment of momelotinib drug-drug interactions via CYP3A metabolism and transporters by Yu Liu Ho, Pete Gorycki, Geraldine Ferron‐Brady, Paul Martin, Georgios Vlasakakis

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CYP2C19 genetic polymorphism in the Vietnamese population by Nhung Phuong Vu, Hoa Thi Thanh Nguyen, Ngoc Thi Bich Tran, Ton Dang Nguyen, Hue Thi Thu Huynh, Xuan Thi Nguyen, Duong Thuy Nguyen, Hai Van Nong, Ha Hai Nguyen

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Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury by Zixiong Zhou, Jing Qi, Yajiao Wu, Chutao Li, Wenqiang Bao, Xiaohuang Lin, An Zhu

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CYP2D6 Reduced Function Variants and Genotype/Phenotype Translations of CYP2D6 Intermediate Metabolizers: Implications for Personalized Drug Dosing in Psychiatry by Espen Molden, Espen Molden, Marin M. Jukić, Marin M. Jukić

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Application of a Physiologically Based Pharmacokinetic Model to Characterize Time-dependent Metabolism of Voriconazole in Children and Support Dose Optimization by Yahui Zhang, Yahui Zhang, Sixuan Zhao, Chuhui Wang, Chuhui Wang, Pengxiang Zhou, Suodi Zhai, Suodi Zhai

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Epoxygenase inactivation exacerbates diet and aging-associated metabolic dysfunction resulting from impaired adipogenesis by Antoni Olona, Ximena Terra, Jeong-Hun Ko, Carme Grau-Bové, Montserrat Pinent, Anna Ardevol, Ana Garcia Diaz, Aida Moreno-Moral, Matthew Edin, David Bishop-Bailey, Darryl C. Zeldin, Timothy J. Aitman, Enrico Petretto, Mayte Blay, Jacques Behmoaras

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Effects of the selective AMPA modulator NBI‐1065845 on the pharmacokinetics of midazolam or ethinyl estradiol-levonorgestrel in healthy adults by Swan Lin, Adrian Ionescu, Jessica Maynard‐Scott, Mike Kennedy, David P. Walling, Maura Furey, Jaskaran B. Singh

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A study on the genetic polymorphisms of CYP3A5 among the Orang Asli in Malaysia using a next generation sequencing platform by Geik Yong Ang, Choo Yee Yu, Richard Johari James, Aminuddin Ahmad, Thuhairah Abdul Rahman, Fadzilah Mohd Nor, Syahrul Azlin Shaari, Adzrool Idzwan Ismail, Lay Kek Teh, Mohd Zaki Salleh

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The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status by Alyssa K. Kuhn, Meina L. Determan, Jessica A. Wright, PharmD, Eric Matey, Jonathan G. Leung

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New drugs to treat multidrug-resistant tuberculosis: the case for bedaquiline by Leibert E, Danckers M, Rom WN

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