Search Results - "cytochrome P450"

The influence of a CYP1A2 polymorphism on the ergogenic effects of caffeine by Womack Christopher J, Saunders Michael J, Bechtel Marta K, Bolton David J, Martin Michael, Luden Nicholas D, Dunham Wade, Hancock Melyssa

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Combining Therapeutic Drug Monitoring and Pharmacokinetic Modelling Deconvolutes Physiological and Environmental Sources of Variability in Clozapine Exposure by Kenneth H. Wills, Stephen J. Behan, Michael J. Nance, Jessica L. Dawson, Thomas M. Polasek, Ashley M. Hopkins, Madelé van Dyk, Andrew Rowland

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Bioengineered miR-27b-3p and miR-328-3p modulate drug metabolism and disposition via the regulation of target ADME gene expression by Xin Li, Ye Tian, Mei-Juan Tu, Pui Yan Ho, Neelu Batra, Ai-Ming Yu

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Physiologically based pharmacokinetic (PBPK) modeling of the role of CYP2D6 polymorphism for metabolic phenotyping with dextromethorphan by Jan Grzegorzewski, Janosch Brandhorst, Matthias König

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Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants by Aarti Sawant‐Basak, Arthur J. Bergman, Jessica Mancuso, Sakambari Tripathy, James R. Gosset, Laure Mendes da Costa, William P. Esler, Roberto A. Calle

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Clinical assessment of gepotidacin (GSK2140944) as a victim and perpetrator of drug-drug interactions via CYP3A metabolism and transporters by Aline Barth, Caroline R. Perry, Shaila Shabbir, Maciej J. Zamek‐Gliszczynski, Sebin Thomas, Etienne F. Dumont, Darin B. Brimhall, Dung Nguyen, Meenakshi Srinivasan, Brandon Swift

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Functional characterization of the defective CYP2C9 variant CYP2C9*18 by Jian Liu, Hao Chen, Shuang‐Hu Wang, Quan Zhou, Pei‐Wu Geng, Yun‐Fang Zhou, Hua‐Lan Wu, Hai‐Feng Shi, Fang Wang, Jie‐Fu Yang, Jian‐Ping Cai, Da‐Peng Dai

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Extragonadal aromatization increases with time after ovariectomy in rats by Chen Boying, Hao Junwei, Tian Zhanzhuang, Zhao Hong

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A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson's disease by Philip Hartz, Tobias Fehlmann, Gudrun Wagenpfeil, Marcus Michael Unger, Marcus Michael Unger, Rita Bernhardt

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Deciphering the Underlying Mechanisms of Formula Le-Cao-Shi Against Liver Injuries by Integrating Network Pharmacology, Metabonomics, and Experimental Validation by Qing Zhao, Qing Zhao, Xia Ren, Xia Ren, Shu-Yue Song, Shu-Yue Song, Ri-Lei Yu, Ri-Lei Yu, Xin Li, Xin Li, Peng Zhang, Peng Zhang, Chang-Lun Shao, Chang-Lun Shao, Chang-Yun Wang, Chang-Yun Wang

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Seed extract of Thai Mucuna pruriens reduced male reproductive damage in rats induced by chronic stress by Natthapol Lapyuneyong, Nareelak Tangsrisakda, Pannawat Choowong-In, Kowit Chaisiwamongkol, Nongnut Uabundit, Tarinee Sawatpanich, Supatcharee Arun, Alexander Tsang-Hsien Wu, Sitthichai Iamsaard

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Antiproliferative and Anti-Inflammatory Activities of Deprungsith Formulation and Its Bioactive Compounds Against Mild Psoriasis and Potential of Metabolic Herb-Drug Interactions by Kesara Na-Bangchang PhD, Monthaka Teerachaisakul PhD, Phunuch Muhamad PhD, Yositha Kasemnitichok BSc, Nattida Sangnarong BSc, Kanyarat Boonprasert PhD, Mayuri Tarasuk PhD, Tullayakorn Plengsuriyakarn PhD

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Systematic review of drug-drug interactions of delta-9-tetrahydrocannabinol, cannabidiol, and Cannabis by Rahul Nachnani, Amy Knehans, Jeffrey D. Neighbors, Paul T. Kocis, Paul T. Kocis, Tzuo Lee, Kayla Tegeler, Thomas Trite, Wesley M. Raup-Konsavage, Kent E. Vrana

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Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation by Mythili Dileepan, Stephanie Rastle-Simpson, Yana Greenberg, Dayanjan S. Wijesinghe, Naren Gajenthra Kumar, Jun Yang, Sung Hee Hwang, Bruce D. Hammock, P. Sriramarao, Savita P. Rao

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Sp1, Instead of AhR, Regulates the Basal Transcription of Porcine CYP1A1 at the Proximal Promoter by Xuan Xie, Xuan Xie, Jun Jiang, Jun Jiang, Wenchu Ye, Wenchu Ye, Ruohong Chen, Ruohong Chen, Yiqun Deng, Yiqun Deng, Jikai Wen, Jikai Wen

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Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro by Li-Li Zou, Fang-Ling Zhao, Yu-Ying Qi, Shuang-Hu Wang, Quan Zhou, Pei-Wu Geng, Yun-Fang Zhou, Qing Zhang, Hao Chen, Da-Peng Dai, Jian-Ping Cai, Fu-Sui Ji, Fu-Sui Ji

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Guidance on Selecting Optimal Steady-State Tacrolimus Concentrations for Continuous IV Perfusion: Insights from Physiologically Based Pharmacokinetic Modeling by Romain Martischang, Argyro Nikolaou, Youssef Daali, Caroline Flora Samer, Jean Terrier

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Sexually Dimorphic Regulation of EET Synthesis and Metabolism: Roles of Estrogen by An Huang, Dong Sun

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Impact of pregnancy related hormones on drug metabolizing enzyme and transport protein concentrations in human hepatocytes by Muluneh M. Fashe, John K. Fallon, Taryn A. Miner, Jacqueline B. Tiley, Philip C. Smith, Craig R. Lee

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The Role of CYP2B6*6 Gene Polymorphisms in 3,5,6-Trichloro-2-pyridinol Levels as a Biomarker of Chlorpyrifos Toxicity Among Indonesian Farmers by Jen Fuk Liem, Dwi A. Suryandari, Safarina G. Malik, Muchtaruddin Mansyur, Dewi S. Soemarko, Aria Kekalih, Imam Subekti, Franciscus D. Suyatna, Bertha Pangaribuan

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