Search Results - "drug development"

Ultra Long-Acting β-Agonists in Chronic Obstructive Pulmonary Disease by Burkes RM, Panos RJ

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Enhancing surgical decision-making in NEC with ResNet18: a deep learning approach to predict the need for surgery through x-ray image analysis by Zhiqing Wu, Ran Zhuo, Xiaobo Liu, Bin Wu, Jian Wang

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MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions by Jak Grimes, Sapna Desai, Neil W. Charter, James Lodge, Rita Moita Santos, Albert Isidro‐Llobet, Andrew M. Mason, Zining Wu, Lawrence A. Wolfe III, Lakshmi Anantharaman, Andrew Green, Angela M. Bridges, Deidre A. Dalmas Wilk, Andrew J. Brown

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New drugs to treat multidrug-resistant tuberculosis: the case for bedaquiline by Leibert E, Danckers M, Rom WN

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Naturally occurring benzophenones and xanthones from Garcinia smeathmannii (Planch. & Triana) Oliv. displayed anti-inflammatory effects by modulating the activities of inflammatory... by Mohammed Jeelani, Hugues Fouotsa, Osama A. Mohammed, Jaber Alfaifi, Salmon Adebayo, Mohammad Muzammil Ahmed, Amar Ibrahim Omer Yahia, Hanan Eissa, Emad Bahashwan, Nahid Ahmed Mohammed, Yousef Ayesh Alotaibi, Ashwaq Yahya Asiri, Assad Rezigallah, Muffarah Hamid Alharthi, Jean Paul Dzoyem, Adamu Imam Isa

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HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa by Christos C. Zouboulis, Xiaoxiao Hou, Henriette von Waldthausen, Konstantin C. Zouboulis, Amir M. Hossini

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Synthesis, solubility, plasma stability, and pharmacological evaluation of novel sulfonylhydrazones designed as anti-diabetic agents by Zapata-Sudo G, da Costa Nunes IK, Araujo JSC, da Silva JS, Trachez MM, da Silva TF, da Costa FP, Sudo RT, Barreiro EJ, Lima LM

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Identification of SARS-CoV-2 Main Protease Inhibitors Using Chemical Similarity Analysis Combined with Machine Learning by Karina Eurídice Juárez-Mercado, Milton Abraham Gómez-Hernández, Juana Salinas-Trujano, Luis Córdova-Bahena, Clara Espitia, Sonia Mayra Pérez-Tapia, José L. Medina-Franco, Marco A. Velasco-Velázquez

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In Vitro Evaluation of Pharmacokinetic Properties of Selected Dual COX-2 and 5-LOX Inhibitors by Jelena Bošković, Vladimir Dobričić, Jelena Savić, Jelena Rupar, Mara Aleksić, Bojan Marković, Olivera Čudina

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Characterization of a novel positive allosteric modulator of the α1A-Adrenergic receptor by Robert S. Papay, Jonathan D. Macdonald, Shaun R. Stauffer, Dianne M. Perez

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CDKN1A as a target of senescence in heart failure: insights from a multiomics study by Rutao Bian, Rutao Bian, Li Zhang, Li Zhang, Dongyu Li, Dongyu Li, Xuegong Xu, Xuegong Xu

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Forskolin rapidly enhances neuron‐like morphological change of directly induced‐neuronal cells from neurofibromatosis type 1 patients by Noriaki Sagata, Shin‐ichi Kano, Masahiro Ohgidani, Shogo Inamine, Yasunari Sakai, Hiroki Kato, Keiji Masuda, Takeshi Nakahara, Makiko Nakahara‐Kido, Shouichi Ohga, Masutaka Furue, Akira Sawa, Shigenobu Kanba, Takahiro A. Kato

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Companies' Health Technology Assessment Strategies and Practices in Australia, Canada, England, France, Germany, Italy and Spain: An Industry Metrics Study by Ting Wang, Ting Wang, Neil McAuslane, Lawrence Liberti, Helga Gardarsdottir, Wim Goettsch, Wim Goettsch, Hubert Leufkens

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Calculating the similarity between prescriptions to find their new indications based on graph neural network by Xingxing Han, Xiaoxia Xie, Ranran Zhao, Yu Li, Pengzhen Ma, Huan Li, Fengming Chen, Yufeng Zhao, Zhishu Tang

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A New Classification of Prodrugs: Regulatory Perspectives by Kuei-Meng Wu

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Morphological, anatomical and molecular characterisation of the leaves of Isoberlinia doka Craib and Stapf and Isoberlinia tomentosa (Harms) Craib and Stapf by Hadiza Bello, Umar A. Katsayal, Aminu A. Ambi, Yusuf B. Abubakar

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Modulation of Cytokine-Induced Astrocytic Endothelin-1 Production as a Possible New Approach to the Treatment of Multiple Sclerosis by Stéphanie Hostenbach, Miguel D'Haeseleer, Miguel D'Haeseleer, Miguel D'Haeseleer, Ron Kooijman, Jacques De Keyser, Jacques De Keyser, Jacques De Keyser

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Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity by Xuemei Zhao, Chengcai Xia, Xiaodan Wang, Hao Wang, Ming Xin, Long Yu, Yulong Liang, Yulong Liang

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Particle size affects pharmacokinetics of milled oxycodone hydrochloride tablet products following nasal insufflation in nondependent, recreational opioid users by Saeid Raofi, Minori Kinjo, Dajun Sun, Zhichuan Li, Heather Boyce, Karthika Natarajan, Mitchell Frost, Liang Zhao, Markham Luke, Robert Lionberger, Debra Kelsh, Myong‐Jin Kim

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Dosing optimization of rituximab for primary membranous nephropathy by population pharmacokinetic and pharmacodynamic study by Hao Liang, Hao Liang, Zhenling Deng, Shu Niu, Weijie Kong, Weijie Kong, Yang Liu, Song Wang, Haiyan Li, Yue Wang, Danxia Zheng, Dongyang Liu, Dongyang Liu, Dongyang Liu

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