Search Results - "drug development"

Characteristics of Early Phase Clinical Trials for Rare Cancers: Insights From Interviews With Stakeholders by M Dooms, R Saesen, I Steemans, J Lansens, I Huys

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Identification of key pharmacodynamic markers of American ginseng against heart failure based on metabolomics and zebrafish model by Rong Dong, Yougang Zhang, Yougang Zhang, Shanjun Chen, Huan Wang, Kaiqing Hu, Huanxin Zhao, Qingping Tian, Kewu Zeng, Songsong Wang, Liwen Han

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Cytotoxic Flavonoids from the Aerial Parts of Stachys lavandulifolia Vahl by Mohammad-Reza Delnavazi, Parisa Saiyarsarai, Saeedeh Jafari-Nodooshan, Mahnaz Khanavi, Saeed Tavakoli, Hormoz Hadavinia, Narguess Yassa

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A comprehensive review of Rubia cordifolia L.: Traditional uses, phytochemistry, pharmacological activities, and clinical applications by Min Wen, Qi Chen, Wang Chen, Jing Yang, Xiaogang Zhou, Chunxiang Zhang, Anguo Wu, Jia Lai, Jianping Chen, Qibing Mei, Shuo Yang, Cai Lan, Jianming Wu, Jianming Wu, Feihong Huang, Long Wang

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Cissus quadrangularis L. hexane extract infused glyoxal cross-linked chitosan-collagen scaffold elicits early osteoinduction by Praseetha R. Nair, P.S. Unnikrishnan, Sachin J. Shenoy, G.S. Sailaja

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Yeast-Based High-Throughput Screens to Identify Novel Compounds Active against Brugia malayi. by Elizabeth Bilsland, Daniel M Bean, Eileen Devaney, Stephen G Oliver

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In vitro susceptibility of Trypanosoma cruzi discrete typing units (DTUs) to benznidazole: A systematic review and meta-analysis. by Andrea Vela, Marco Coral-Almeida, Denis Sereno, Jaime A Costales, Christian Barnabé, Simone Frédérique Brenière

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Modulating the RPS27A/PSMD12/NF-κB pathway to control immune response in mouse brain ischemia-reperfusion injury by Xiaocheng Li, Ming Qiao, Yan Zhou, Yan Peng, Gang Wen, Chenchen Xie, Yamei Zhang

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An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans. by Meghan A Guzman, Anastasia R Rugel, Reid S Tarpley, Sevan N Alwan, Frédéric D Chevalier, Dmytro P Kovalskyy, Xiaohang Cao, Stephen P Holloway, Timothy J C Anderson, Alexander B Taylor, Stanton F McHardy, Philip T LoVerde

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In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens by Hongfei Pi, Henrietta Venter, Cecilia C. Russell, Kelly A. Young, Adam McCluskey, Stephen W. Page, Abiodun D. Ogunniyi, Darren J. Trott

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Evaluation of the antidiarrheal activity of the leaf extract of Parquetina nigrescens and formulation into oral suspensions by Kola-Mustapha AT, Ghazali YO, Ayotunde HT, Atunwa SA, Usman SO

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Ethnobotanical study of traditional medicinal plants used by the local Gamo people in Boreda Abaya District, Gamo Zone, southern Ethiopia by Juhar Zemede, Tegenu Mekuria, Clintone Onyango Ochieng, Guy Eric Onjalalaina, Guang-Wan Hu

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Development and content validation of the Symptoms Evolution of COVID-19: a patient-reported electronic daily diary in clinical and real-world studies by Diana Rofail, Nadine McGale, Joseph Im, Alissa Rams, Krystian Przydzial, Vera Mastey, Sumathi Sivapalasingam, Anna J. Podolanczuk

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An accelerated surface-mediated stress assay of antibody instability for developability studies by Marie R.G. Kopp, Adriana-Michelle Wolf Pérez, Marta Virginia Zucca, Umberto Capasso Palmiero, Brigitte Friedrichsen, Nikolai Lorenzen, Paolo Arosio

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Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression by Xiang Li, Neelakshi Gohain, Si Chen, Yinghua Li, Xiaoyuan Zhao, Bo Li, William D. Tolbert, Wangxiao He, Marzena Pazgier, Honggang Hu, Wuyuan Lu

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Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm by Nesrine Lajmi, Sofia Alves-Vasconcelos, Apostolos Tsiachristas, Andrew Haworth, Kerrie Woods, Charles Crichton, Theresa Noble, Hizni Salih, Kinga A. Várnai, Harriet Branford-White, Liam Orrell, Andrew Osman, Kevin M. Bradley, Lara Bonney, Daniel R. McGowan, Jim Davies, Matthew S. Prime, Andrew Bassim Hassan

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Predicting Drug-Induced Liver Injury Using Machine Learning on a Diverse Set of Predictors by Temidayo Adeluwa, Brett A. McGregor, Kai Guo, Kai Guo, Junguk Hur

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Patient-centered pharmacovigilance: priority actions from the inherited bleeding disorders community by Fiona Robinson, Sonji Wilkes, Nathan Schaefer, Miriam Goldstein, Michelle Rice, Johanna Gray, Sharon Meyers, Leonard A. Valentino

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Challenges and opportunities for China entering global research and development for emerging infectious diseases: a case study from Ebola experience by Chao Li, Jing-Yi Chen, Yang-Mu Huang

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Chemico-pharmacological evaluations of the dwarf elephant ear (Colocasia affinis Schott) plant metabolites and extracts: health benefits from vegetable source by Safaet Alam, Safaet Alam, Fahmida Tasnim Richi, Hasin Hasnat, Firoj Ahmed, Nazim Uddin Emon, Md. Jasim Uddin, G. M. Masud Rana, Shuanghu Wang, Mst. Sarmina Yeasmin, Nazim Uddin Ahmed, Md. Salim Khan, Abdullah Al Mamun

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