Search Results - "drug development"

Potential of medicinal plants as antimalarial agents: a review of work done at Kenya Medical Research Institute by Beatrice Irungu, Erick Okari, Mary Nyangi, Sospeter Njeru, Lilian Koech

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Model‐based meta‐analysis to quantify the effects of short interfering RNA therapeutics on hepatitis B surface antigen turnover in hepatitis B‐infected mice by Louis Sandra, Huybrecht T'jollyn, An Vermeulen, Oliver Ackaert, Juan‐Jose Perez‐Ruixo

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Identification of novel modulators of a schistosome transient receptor potential channel targeted by praziquantel by Evgeny G. Chulkov, Emery Smith, Claudia M. Rohr, Nawal A. Yahya, Sang-Kyu Park, Louis Scampavia, Timothy P. Spicer, Jonathan S. Marchant

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Malaria's molecular dance: Mechanism, therapies, and emerging insights by Nabila Ananda, Athaya Sabina, Ulfa Rahmadani, Ali Syahrizal, Nabillah Deskya, Sinta Maria, Muhammad Riza, Lusi Rahmadia, Anni Holila, Dwi Putri, Kevin Gabriel, Ratna Sari Zai, Mega Carensia, Princella Halim, Naomi Regina, Dinda Rizka, Aulia Syahfitri, Tessa Rotua, Maria Belen, Fahmy Nanda, Rizzanda Pramuditya, Khairunnisa Khairunnisa, Emil Salim, Fahrul Nurkolis, Chindy Umaya, Rony Abdi Syahputra

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Antioxidant and anti-inflammatory activities of methanol and aqueous extracts of Sargassum wightii by Sradhasini Rout, Bandana Rath, Subrat Kumar Bhattamisra, Ishani Rath, Anjan Kumar

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Synthesis and Antiproliferative Evaluation of 3-Chloroazetidin-2-ones with Antimitotic Activity: Heterocyclic Bridged Analogues of Combretastatin A-4 by Azizah M. Malebari, Shu Wang, Thomas F. Greene, Niamh M. O'Boyle, Darren Fayne, Mohemmed Faraz Khan, Seema M. Nathwani, Brendan Twamley, Thomas McCabe, Daniela M. Zisterer, Mary J. Meegan

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Characterization of renal biomarkers for use in clinical trials: biomarker evaluation in healthy volunteers by Brott DA, Adler SH, Arani R, Lovick SC, Pinches M, Furlong ST

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Repurposing Anti-Cancer Drugs for COVID-19 Treatment by Borcherding N, Jethava Y, Vikas P

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Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition by James J. Beaudoin, Kyunghee Yang, Jeffry Adiwidjaja, Jeffry Adiwidjaja, Guncha Taneja, Paul B. Watkins, Scott Q. Siler, Brett A. Howell, Jeffrey L. Woodhead

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Enterolactone has stronger effects than enterodiol on ovarian cancer by Huidi Liu, Jianrui Liu, Siwen Wang, Zheng Zeng, Ting Li, Yongfang Liu, Emilio Mastriani, Qing-Hai Li, Hong-Xia Bao, Yu-Jie Zhou, Xiaoyu Wang, Sijing Hu, Shan Gao, Yingying Qi, Zhihang Shen, Hongyue Wang, Miao Yu, Tingting Gao, Randal N. Johnston, Shu-Lin Liu

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Non-Small Cell Lung Cancer Symptom Assessment Questionnaire: Psychometric Performance and Regulatory Qualification of a Novel Patient-Reported Symptom Measure by Donald M. Bushnell, MA, Thomas M. Atkinson, PhD, Kelly P. McCarrier, PhD, Astra M. Liepa, PharmD, Kendra P. DeBusk, PhD, Stephen Joel Coons, PhD

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MET gene alterations predict poor survival following chemotherapy in patients with advanced cancer by Jihoon Ko, Jaeyun Jung, Seung Tae Kim, Jung Yong Hong, Sehhoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Soomin Ahn, Kyoung-Mee Kim, Won Ki Kang, Jeeyun Lee

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PBPK-based dose finding for sildenafil in pregnant women for antenatal treatment of congenital diaphragmatic hernia by Julia Macente, Nina Nauwelaerts, Francesca M. Russo, Jan Deprest, Karel Allegaert, Karel Allegaert, Karel Allegaert, Bart Lammens, Rodolfo Hernandes Bonan, Jessica M. Turner, Sailesh Kumar, Andrea Diniz, Frederico S. Martins, Pieter Annaert, Pieter Annaert

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Coproporphyrin I Can Serve as an Endogenous Biomarker for OATP1B1 Inhibition: Assessment Using a Glecaprevir/Pibrentasvir Clinical Study by Hari V. Kalluri, Ryota Kikuchi, Sheryl Coppola, Jeffrey Schmidt, Mohamed‐Eslam F. Mohamed, Daniel A.J. Bow, Ahmed H. Salem

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Differential Expression of <i>ABC</i> Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat by Wandong Zhang, Qing Yan Liu, Arsalan S. Haqqani, Ziying Liu, Caroline Sodja, Sonia Leclerc, Ewa Baumann, Christie E. Delaney, Eric Brunette, Danica B. Stanimirovic

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Proteomics: a subcellular look at spermatozoa by Yadav Satya P, Benjamin David J, Kashou Anthony H, du Plessis Stefan S, Agarwal Ashok

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Model-dependent pharmacokinetic analysis of enalapril administered to healthy adult volunteers using orodispersible minitablets for use in pediatrics by Faisal M, Cawello W, Burckhardt BB, Laer S

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Past and current perspective on new therapeutic targets for Type-II diabetes by Patil PD, Mahajan UB, Patil KR, Chaudhari S, Patil CR, Agrawal YO, Ojha S, Goyal SN

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In Vitro-In Vivo Correlation (IVIVC) Population Modeling for the In Silico Bioequivalence of a Long-Acting Release Formulation of Progesterone by Elena M. Tosca, Maurizio Rocchetti, Elena Pérez, Conchi Nieto, Paolo Bettica, Jaime Moscoso del Prado, Paolo Magni, Giuseppe De Nicolao

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Design and Development of a Behaviorally Active Recombinant Neurotrophic Factor by Pekas NJ, Petersen JL, Sathyanesan M, Newton SS

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